Search Results - "Crouch, P J"

Endogenous Cu in the central nervous system fails to satiate the elevated requirement for Cu in a mutant SOD1 mouse model of ALS by Hilton, J. B, White, A. R, Crouch, P. J

“…Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease, a fatal degenerative disorder in which motor neurons in the central…”
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Anatomical redistribution of endogenous copper in embryonic mice overexpressing SOD1 by Kysenius, K, Hilton, J. B, Paul, B, Hare, D. J, Crouch, P. J

“…Mutations in the copper (Cu)- and zinc (Zn)-binding metalloenzyme Cu/Zn-superoxide dismutase (SOD1) cause familial forms of amyotrophic lateral sclerosis…”
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Tau-mediated iron export prevents ferroptotic damage after ischemic stroke by Tuo, Q-z, Lei, P, Jackman, K A, Li, X-l, Xiong, H, Li, X-l, Liuyang, Z-y, Roisman, L, Zhang, S-t, Ayton, S, Wang, Q, Crouch, P J, Ganio, K, Wang, X-c, Pei, L, Adlard, P A, Lu, Y-m, Cappai, R, Wang, J-z, Liu, R, Bush, A I

“…Functional failure of tau contributes to age-dependent, iron-mediated neurotoxicity, and as iron accumulates in ischemic stroke tissue, we hypothesized that…”
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Decreased spinal cord motor neuron numbers in mice depleted of central nervous system copper by Liddell, J R, Hilton, J B W, Wang, Y J, Billings, J L, Nikseresht, S, Kysenius, K, Fuller-Jackson, J P, Hare, D J, Crouch, P J

“…Disrupted copper availability in the central nervous system (CNS) is implicated as a significant feature of the neurodegenerative disease amyotrophic lateral…”
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X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder by Grubman, A, James, S A, James, J, Duncan, C, Volitakis, I, Hickey, J L, Crouch, P J, Donnelly, P S, Kanninen, K M, Liddell, J R, Cotman, S L, de Jonge, White, A R

“…Biometals such as zinc, iron, copper and calcium play key roles in diverse physiological processes in the brain, but can be toxic in excess. A hallmark of…”
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Free amino acids in claw muscle and haemolymph from Australian freshwater crayfish at different stages of the moult cycle by Dooley, P.C., Crouch, P.J., West, J.M.

“…Amino acids were measured in claw muscle and haemolymph in the freshwater decapod crustacean, Cherax destructor, at different stages of the moult cycle. The…”
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Mitochondria in aging and Alzheimer's disease by Crouch, P J, Cimdins, K, Duce, J A, Bush, A I, Trounce, I A

“…Two significant risk factors are inextricably linked with Alzheimer's disease: advancing age, and accumulation of the amyloid-beta peptide. Over the age of 65…”
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Oral Treatment with CuII(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis by Roberts, B. R., Lim, N. K. H., McAllum, E. J., Donnelly, P. S., Hare, D. J., Doble, P. A., Turner, B. J., Price, K. A., Chun Lim, S., Paterson, B. M., Hickey, J. L., Rhoads, T. W., Williams, J. R., Kanninen, K. M., Hung, L. W., Liddell, J. R., Grubman, A., Monty, J.-F., Llanos, R. M., Kramer, D. R., Mercer, J. F. B., Bush, A. I., Masters, C. L., Duce, J. A., Li, Q.-X., Beckman, J. S., Barnham, K. J., White, A. R., Crouch, P. J.

“…Mutations in the metallo-protein Cu/Zn-superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS) in humans and an expression level-dependent…”
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Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain by Lim, Nastasia K H, Hung, Lin W, Pang, Terence Y, Mclean, Catriona A, Liddell, Jeffrey R, Hilton, James B, Li, Qiao-Xin, White, Anthony R, Hannan, Anthony J, Crouch, Peter J

“…All cases of Huntington's disease (HD) are caused by mutant huntingtin protein (mhtt), yet the molecular mechanisms that link mhtt to disease symptoms are not…”
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X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorderElectronic supplementary information (ESI) available: Supplementary Fig. 1-7. See DOI: 10.1039/c4sc00316k by Grubman, A, James, S. A, James, J, Duncan, C, Volitakis, I, Hickey, J. L, Crouch, P. J, Donnelly, P. S, Kanninen, K. M, Liddell, J. R, Cotman, S. L, de Jonge, M. D, White, A. R

“…Biometals such as zinc, iron, copper and calcium play key roles in diverse physiological processes in the brain, but can be toxic in excess. A hallmark of…”
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Metallo-complex activation of neuroprotective signalling pathways as a therapeutic treatment for Alzheimer's disease by Bica, Laura, Crouch, Peter J, Cappai, Roberto, White, Anthony R

“…Alzheimer's disease is the most common neurodegenerative disease of the elderly and although some drugs may delay cognitive impairment, an effective treatment…”
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Linker Histone H1 Binds to Disease Associated Amyloid-like Fibrils by Duce, James A., Smith, David P., Blake, Rachel E., Crouch, Peter J., Li, Qiao-Xin, Masters, Colin L., Trounce, Ian A.

“…Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most prevalent neurodegenerative diseases of the central nervous system. These two diseases…”
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Enterprises, manufactories, and small industrial communities, 1850-1914 by Crouch, P J

“…The financial advantage of mass production, during the second half of the nineteenth century, caused many manufacturing companies to be formed and various…”
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The particularistic president: executive branch politics and political inequality by Crouch, J P

“…Kriner (Boston Univ.) and [Reeves] (Washington Univ., St…”
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Speaking with the people's voice: how presidents invoke public opinion by Crouch, J P

“…Drury (Wabash College) explores "invoked public opinion" and the manner in which "modern presidents deploy references to the beliefs and values of US citizens…”
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Conservative internationalism: armed diplomacy under Jefferson, Polk, Truman, and Reagan by Crouch, J P

“…Nau (George Washington Univ.) articulates a theory of "conservative internationalism," a fourth major approach to international affairs that draws elements…”
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War powers: the politics of constitutional authority by Crouch, J P

“…51-4140 JK339 2012-39981 CIP Zeisberg, Mariah. War powers: the politics of constitutional authority. Princeton, 2013. 276p index afp ISBN 0691157227, $29.95;…”
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Thinking about the presidency: the primacy of power by Crouch, J P

“…51-2360 JK516 2012-42074 CIP Howell, William G. Thinking about the presidency: the primacy of power, by William G. Howell with David Milton Brent. Princeton,…”
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Elusive victories: the American presidency at war by Crouch, J P

“…50-2947 JK558 2011-41946 CIP Polsky, Andrew J. Elusive victories: the American presidency at war. Oxford, 2012. 445p index afp ISBN 0199860939, $29.95; ISBN…”
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After broadcast news: media regimes, democracy, and the new information environment by Crouch, J P

“…[Bruce A. Williams] (Univ. of Virginia) and [Michael X. Delli Carpini] (dean, Annenberg School for Communication) contend that the current "media regime," the…”
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