Search Results - "Crossley, K J"
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Adverse respiratory patterns in near-term spontaneously breathing newborn lambs with elevated airway liquid volumes at birth
Published in Frontiers in pediatrics (16-04-2024)“…Recent evidence indicates that respiratory distress (RD) in near-term infants is caused by elevated airway liquid (EL) volume at the beginning of air-breathing…”
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Respiratory patterns in spontaneously breathing near-term lambs delivered by caesarean section under spinal anaesthesia
Published in Frontiers in pediatrics (09-10-2023)“…Introduction The transition to newborn life has typically been studied in intubated and mechanically ventilated newborn lambs delivered via caesarean section…”
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Assessing lung aeration using ultrasound after birth in near-term lambs at risk of respiratory distress
Published in Frontiers in pediatrics (22-05-2023)“…Optimizing respiratory support after birth requires real-time feedback on lung aeration. We hypothesized that lung ultrasound (LUS) can accurately monitor the…”
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Assessment of gas flow waves for endotracheal tube placement in an ovine model of neonatal resuscitation
Published in Resuscitation (01-06-2010)“…Abstract Aim Clinical assessment and end-tidal CO2 (ETCO2 ) detectors are routinely used to verify correct endotracheal tube (ETT) placement. However, ETCO2…”
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Physiological effects of partial amniotic carbon dioxide insufflation with cold, dry vs heated, humidified gas in a sheep model
Published in Ultrasound in obstetrics & gynecology (01-03-2019)“…ABSTRACT Objective Partial amniotic carbon dioxide (CO2) insufflation (PACI) is used to improve visualization and facilitate complex fetoscopic surgery…”
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Placental gas exchange during amniotic carbon dioxide insufflation in sheep
Published in Ultrasound in obstetrics & gynecology (01-02-2021)“…ABSTRACT Objective Insufflation of the amniotic cavity with carbon dioxide (CO2) is used clinically to improve visibility during complex fetoscopic surgery…”
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Antenatal sildenafil treatment improves neonatal pulmonary hemodynamics and gas exchange in lambs with diaphragmatic hernia
Published in Ultrasound in obstetrics & gynecology (01-10-2019)“…ABSTRACT Objectives Infants with congenital diaphragmatic hernia (CDH) are predisposed to pulmonary hypertension after birth, owing to lung hypoplasia that…”
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Increased lung expansion alters lung growth but not alveolar epithelial cell differentiation in newborn lambs
Published in American journal of physiology. Lung cellular and molecular physiology (01-02-2007)“…Although increased lung expansion markedly alters lung growth and epithelial cell differentiation during fetal life, the effect of increasing lung expansion…”
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The effect of oxygen content during an initial sustained inflation on heart rate in asphyxiated near-term lambs
Published in Archives of disease in childhood. Fetal and neonatal edition (01-07-2015)“…At birth, an initial sustained inflation (SI) uniformly aerates the lungs, increases arterial oxygenation and rapidly improves circulatory recovery in…”
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Accurate measures of regional lung air volumes from chest X-rays of small animals
Published 07-04-2022“…We present a robust technique for calculating regional volume changes within the lung from X-ray radiograph sequences captured during ventilation, without the…”
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Characterisation of GABA A receptors in fetal, neonatal and adult ovine brain: region and age related changes and the effects of allopregnanolone
Published in Neuropharmacology (10-07-2000)“…Progesterone metabolites acting via GABA A receptors suppress central nervous system (CNS) activity. The aim of the present study was to examine binding…”
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Single Sustained Inflation followed by Ventilation Leads to Rapid Cardiorespiratory Recovery but Causes Cerebral Vascular Leakage in Asphyxiated Near-Term Lambs
Published in PloS one (14-01-2016)“…A sustained inflation (SI) rapidly restores cardiac function in asphyxic, bradycardic newborns but its effects on cerebral haemodynamics and brain injury are…”
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Suppression of arousal by progesterone in fetal sheep
Published in Reproduction fertility and development (1997)“…The high rate of progesterone synthesis by the placenta in late gestation exposes the ovine fetus to high concentrations of progesterone and its metabolites…”
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Multicentre, randomised controlled trial of physiological-based cord clamping versus immediate cord clamping in infants with a congenital diaphragmatic hernia (PinC): statistical analysis plan
Published in Current controlled trials in cardiovascular medicine (20-03-2024)“…Infants born with congenital diaphragmatic hernia (CDH) are at high risk of respiratory insufficiency and pulmonary hypertension. Routine practice includes…”
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Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung
Published in Respiratory research (20-08-2018)“…Prenatal glucocorticoid treatment decreases alveolar tissue volumes and facilitates fetal lung maturation, however the mechanisms responsible are largely…”
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Robust propagation-based phase retrieval for CT in proximity to highly attenuating objects
Published 29-01-2023“…X-ray imaging is a fast, precise and non-invasive method of imaging which, combined with computed tomography, provides detailed 3D rendering of samples…”
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Positive end-expiratory pressure differentially alters pulmonary hemodynamics and oxygenation in ventilated, very premature lambs
Published in Journal of applied physiology (1985) (01-10-2005)“…1 Fetal and Neonatal Research Group, Department of Physiology and 4 Centre for Biomedical Engineering, Monash University; 2 Department of Neonatal Services,…”
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Characterisation of GABA sub(A) receptors in fetal, neonatal and adult ovine brain: Region and age related changes and the effects of allopregnanolone
Published in Neuropharmacology (01-07-2000)“…Progesterone metabolites acting via GABA sub(A) receptors suppress central nervous system (CNS) activity. The aim of the present study was to examine binding…”
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Characterisation of GABAA receptors in fetal, neonatal and adult ovine brain : Region and age related changes and the effects of allopregnanolone
Published in Neuropharmacology (01-08-2000)Get full text
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Steroid-sensitive GABA A receptors in the fetal sheep brain
Published in Neuropharmacology (01-09-2003)“…Neuroactive steroids such as allopregnanolone (3 α-hydroxy-5 α-pregnan-20-one) influence central nervous system (CNS) excitability by increasing GABA (gamma…”
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