Search Results - "Cross, R. A."

Review: Mechanochemistry of the kinesin‐1 ATPase by Cross, R. A.

“…ABSTRACT Kinesins are P‐loop NTPases that can do mechanical work. Like small G‐proteins, to which they are related, kinesins execute a program of active site…”
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Mechanics of the kinesin step by Cross, R. A, Carter, N. J

“…Kinesin is a molecular walking machine that organizes cells by hauling packets of components directionally along microtubules. The physical mechanism that…”
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Antebrachiometacarpal arthrodesis in five dogs by Lewis, ST, Lewis, DD, Cross, AR, Radasch, RM, Boekhout‐Ta, C

“…Case reports Five dogs (4 with severe carpal contracture, 1 with a chronically infected carpal joint) underwent antebrachiometacarpal arthrodesis. Excision of…”
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Thinning, movement, and volume loss of residual cortical tissue occurs after stroke in the adult rat as identified by histological and magnetic resonance imaging analysis by Karl, J.M, Alaverdashvili, M, Cross, A.R, Whishaw, I.Q

“…Abstract Plasticity of residual cortical tissue has been identified as an important mediator of functional post-stroke recovery. Many studies have been…”
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HLA Class II Antibody Activation of Endothelial Cells Promotes Th17 and Disrupts Regulatory T Lymphocyte Expansion by Lion, J., Taflin, C., Cross, A. R., Robledo‐Sarmiento, M., Mariotto, E., Savenay, A., Carmagnat, M., Suberbielle, C., Charron, D., Haziot, A., Glotz, D., Mooney, N.

“…Kidney transplantation is the most successful treatment option for patients with end‐stage renal disease, and chronic antibody‐mediated rejection is the…”
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Monastrol stabilises an attached low-friction mode of Eg5 by Crevel, I.M-T.C, Alonso, M.C, Cross, R.A

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Involvement of an NAD(P)H oxidase as a pO2 sensor protein in the rat carotid body by CROSS, A. R, HENDERSON, L, JONES, O. T. G, DELPIANO, M. A, HENTSCHEL, J, ACKER, H

“…The rat carotid body tissue reveals a photometrically measurable haem signal with absorbance maxima at 560 nm, 518 nm and 425 nm, suggesting the presence of a…”
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Molecular Motors: Dynein's Gearbox by Cross, R.A

“…A new optical trapping study shows that the stepsize of cytoplasmic dynein varies according to the applied force, suggesting that this motor can change gear…”
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Identification of a superoxide-generating NADPH oxidase system in human fibroblasts by MEIER, B, CROSS, A. R, HANCOCK, J. T, KAUP, F. J, JONES, O. T. G

“…Human fibroblasts have the capacity to release superoxide radicals upon stimulation of an electron transport system similar to the NADPH oxidase of leukocytes…”
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The conformational cycle of kinesin by Cross, R. A., Crevel, I., Carter, N. J., Alonso, M. C., Hirose, K., Amos, L. A.

“…The stepping mechanism of kinesin can be thought of as a programme of conformational changes. We briefly review protein chemical, electron microscopic and…”
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Inhibitors of the leukocyte superoxide generating oxidase: mechanisms of action and methods for their elucidation by Cross, A R

“…Oxygen radical production by phagocytic cells is currently receiving a great deal of attention as the role of radical damage is becoming apparent in…”
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Three-Dimensional Cryoelectron Microscopy of Dimeric Kinesin and ncd Motor Domains on Microtubules by Hirose, Keiko, Lockhart, Andrew, Cross, Robert A., Amos, Linda A.

“…Kinesin and ncd motor proteins are homologous in sequence yet move in opposite directions along microtubules. We have previously shown that monomeric kinesin…”
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Origins of reversed directionality in the ncd molecular motor by Lockhart, A., Cross, R.A.

“…The head or motor domain of the ncd (non‐claret disjunctional) molecular motor is 41% identical to that of kinesin, yet moves along microtubules in the…”
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Kinetic evidence for low chemical processivity in ncd and Eg5 by Crevel, I.M-T.C., Lockhart, A., Cross, R.A.

“…The kinesin molecular motor “walks” processively along microtubules, touching down with alternate motor domains and transiently bridging between sites spaced 8…”
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Chronic granulomatous disease by Heyworth, Paul G, Cross, Andrew R, Curnutte, John T

“…Chronic granulomatous disease (CGD) is a primary immunodeficiency that affects phagocytes of the innate immune system and is characterized by a greatly…”
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Expression of the N-terminal domain of dystrophin in E. coli and demonstration of binding to F-actin by Way, M., Pope, B., Cross, R.A., Kendrick-Jones, J., Weeds, A.G.

“…The N-terminal head domain of human dystrophin has been expressed in soluble form and high yield in E. coli, allowing us to test the previously unconfirmed…”
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Multiphoton versus confocal high resolution z‐sectioning of enhanced green fluorescent microtubules: increased multiphoton photobleaching within the focal plane can be compensated using a Pockels cell and dual widefield detectors by Drummond, D. R., Carter, N., Cross, R. A.

“…Summary Multiphoton excitation was originally projected to improve live cell fluorescence imaging by minimizing photobleaching effects outside the focal plane,…”
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A protein-making motor protein by Cross, R. A

“…It is argued that the ribosomal protein that catalyzes the mRNA translocation step--elongation factor G--does not simply bind and dissociate once per notch but…”
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Reversing the kinesin ratchet - a diverting tail by Cross, R. A

“…Kinesins are molecular motors that are mechanically programmed to move along microtubules in one direction only--towards either the rapidly growing plus ends…”
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Nucleotide-dependent structural changes in dimeric NCD molecules complexed to microtubules by Hirose, K, Cross, R A, Amos, L A

“…Complexes consisting of motor domains of the kinesin-like protein ncd bound to reassembled brain microtubules were visualised using cryoelectron microscopy and…”
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