Search Results - "Cross, A.M"

Negative Input-Resistance Compensator for a Constant Power Load by Xinyun Liu, Forsyth, A.J., Cross, A.M.

“…A negative input-resistance compensator is designed to stabilize a power electronic brushless dc motor drive with constant power-load characteristics. The…”
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The use of pelvic binders in the emergent management of potential pelvic trauma by Chesser, T.J.S, Cross, A.M, Ward, A.J

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Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging by Siegel, T. Nicolai, Hekstra, Doeke R., Cross, George A.M.

“…Trypanosoma brucei has two DNA compartments: the nucleus and the kinetoplast. DNA replication of these two compartments only partially coincides. Woodward and…”
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Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei by Siegel, T Nicolai, Hekstra, Doeke R, Kemp, Louise E, Figueiredo, Luisa M, Lowell, Joanna E, Fenyo, David, Wang, Xuning, Dewell, Scott, Cross, George A M

“…Unusually for a eukaryote, genes transcribed by RNA polymerase II (pol II) in Trypanosoma brucei are arranged in polycistronic transcription units. With one…”
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Cholesterol import fails to prevent catalyst-based inhibition of ergosterol synthesis and cell proliferation of Trypanosoma brucei by Zhou, Wenxu, Cross, George A.M., Nes, W. David

“…Trypanosoma brucei (TB) cultured in rat blood, bovine serum, or lipid-depleted serum generated distinct differences in cholesterol availability. Whereas cell…”
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The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism by Das, Anish, Morales, Rachel, Banday, Mahrukh, Garcia, Stacey, Hao, Li, Cross, George A M, Estevez, Antonio M, Bellofatto, Vivian

“…RNA-binding proteins that target mRNA coding regions are emerging as regulators of post-transcriptional processes in eukaryotes. Here we describe a newly…”
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Lower limb traumatic amputation – the importance of pelvic binding for associated pelvic fractures in blast injury by Cross, A.M, Davis, C, Taylor, M, de Mello, W, Matthews, J.J

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Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites by Siegel, Tim Nicolai, Hekstra, Doeke R, Wang, Xuning, Dewell, Scott, Cross, George A.M

“…Transcription of protein-coding genes in trypanosomes is polycistronic and gene expression is primarily regulated by post-transcriptional mechanisms. Sequence…”
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Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites by Navarro, M, Cross, G.A.M, Wirtz, E

“…Trypanosoma brucei is an extracellular protozoan parasite that cycles between mammalian hosts and the tsetse vector. In bloodstream‐form trypanosomes, only one…”
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TOPO3α Influences Antigenic Variation by Monitoring Expression-Site-Associated VSG Switching in Trypanosoma brucei by Kim, Hee-Sook, Cross, George A.M

“…Homologous recombination (HR) mediates one of the major mechanisms of trypanosome antigenic variation by placing a different variant surface glycoprotein (VSG)…”
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Epigenetic regulation in African trypanosomes: a new kid on the block by Figueiredo, Luisa M, Cross, George A. M, Janzen, Christian J

“…Key Points Trypanosoma brucei , the causative agent of sleeping sickness in humans, diverged from the highest eukaryotic lineage several hundred million years…”
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Gene expression in Trypanosoma brucei : lessons from high-throughput RNA sequencing by Siegel, T. Nicolai, Gunasekera, Kapila, Cross, George A.M, Ochsenreiter, Torsten

“…Trypanosoma brucei undergoes major biochemical and morphological changes during its development from the bloodstream form in the mammalian host to the…”
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A histone methyltransferase modulates antigenic variation in African trypanosomes by Figueiredo, Luisa M, Janzen, Christian J, Cross, George A M

“…To evade the host immune system, several pathogens periodically change their cell-surface epitopes. In the African trypanosomes, antigenic variation is…”
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199: Between-country and Between-specialty Differences in Approach to Early Septic Shock by Reade, M.C, Huang, D.T, Yealy, D.M, Peake, S.L, Cross, A.M, Angus, D.C

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Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei by Cliffe, Laura J, Siegel, T.Nicolai, Marshall, Marion, Cross, George A.M, Sabatini, Robert

“…Base J is a hypermodified DNA base localized primarily to telomeric regions of the genome of Trypanosoma brucei. We have previously characterized two…”
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Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei by Hovel-Miner, Galadriel A, Boothroyd, Catharine E, Mugnier, Monica, Dreesen, Oliver, Cross, George A M, Papavasiliou, F Nina

“…Trypanosoma brucei is a master of antigenic variation and immune response evasion. Utilizing a genomic repertoire of more than 1000 Variant Surface…”
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Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei by Wright, Jessica R., Siegel, T. Nicolai, Cross, George A.M.

“…The histone modification H3K4me3 is enriched at probable sites of transcription initiation in Trypanosoma brucei and co-localizes with H4K10ac and histone…”
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Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei by Güther, Maria Lucia Sampaio, Leal, Simone, Morrice, Nicholas A., Cross, George A.M., Ferguson, Michael A.J.

“…Inositol acylation is an obligatory step in glycosylphosphatidylinositol (GPI) biosynthesis whereas mature GPI anchors often lack this modification. The GPI…”
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Strategies to construct null and conditional null Trypanosoma brucei mutants using Cre-recombinase and loxP by Kim, Hee-Sook, Li, Zhen, Boothroyd, Catharine, Cross, George A.M.

“…The first KO strategy allows continuous reuse of selection markers for double or triple mutant construction and the second allows the molecular functions of…”
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Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes by Kawahara, Taemi, Siegel, T. Nicolai, Ingram, Alexandra K, Alsford, Sam, Cross, George A.M, Horn, David

“…Chromatin modification is important for virtually all aspects of DNA metabolism but little is known about the consequences of such modification in…”
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