Search Results - "Croq, Françoise"
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Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to vertebrate ionized calcium‐binding adapter molecule 1 (Iba1/alias aif‐1)
Published in Developmental neurobiology (Hoboken, N.J.) (01-10-2014)“…ABSTRACT The Ionized calcium‐Binding Adapter molecule 1 (Iba1), also known as Allograft Inflammatory Factor 1 (AIF‐1), is a 17 kDa cytokine‐inducible protein,…”
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Modulation properties of factors released by bone marrow stromal cells on activated microglia: an in vitro study
Published in Scientific reports (19-12-2014)“…In the present paper we develop a new non-cell based (cell-free) therapeutic approach applied to BV2 microglial cells and spinal cord derived primary microglia…”
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The Leech Nervous System: A Valuable Model to Study the Microglia Involvement in Regenerative Processes
Published in Clinical & developmental immunology (01-01-2013)“…Microglia are intrinsic components of the central nervous system (CNS). During pathologies in mammals, inflammatory processes implicate the resident microglia…”
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Alterations of protein composition along the rostro-caudal axis after spinal cord injury: proteomic, in vitro and in vivo analyses
Published in Frontiers in cellular neuroscience (17-04-2014)“…Based on proteomic analyses we investigated the differences of released molecules in the conditioned media (CM) from the spinal cord central lesion and…”
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Hedistin: A novel antimicrobial peptide containing bromotryptophan constitutively expressed in the NK cells-like of the marine annelid, Nereis diversicolor
Published in Developmental and comparative immunology (2007)“…A novel antimicrobial peptide, named hedistin was identified from the coelomocytes of Nereis diversicolor. Hedistin shows no obvious similarities with other…”
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Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis
Published in Journal of neuroinflammation (22-02-2012)“…In invertebrates, the medicinal leech is considered to be an interesting and appropriate model to study neuroimmune mechanisms. Indeed, this non-vertebrate…”
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Calreticulin contributes to C1q-dependent recruitment of microglia in the leech Hirudo medicinalis following a CNS injury
Published in Medical science monitor (19-04-2014)“…The medicinal leech is considered as a complementary and appropriate model to study immune functions in the central nervous system (CNS). In a context in which…”
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Is complement good, bad, or both? New functions of the complement factors associated with inflammation mechanisms in the central nervous system
Published in European cytokine network (01-09-2009)“…The complement system is well known as an enzyme cascade that helps to defend against infections. Indeed, this ancestral system bridges innate and adaptive…”
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Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons
Published in International journal of molecular sciences (19-12-2018)“…In healthy or pathological brains, the neuroinflammatory state is supported by a strong communication involving microglia and neurons. Recent studies indicate…”
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ALK4/5-dependent TGF-β signaling contributes to the crosstalk between neurons and microglia following axonal lesion
Published in Scientific reports (03-05-2019)“…Neuronal activity is closely influenced by glia, especially microglia which are the resident immune cells in the central nervous system (CNS). Microglia in…”
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A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis
Published in Glia (01-11-2010)“…In contrast to mammals, the medicinal leech Hirudo medicinalis can completely repair its central nervous system (CNS) after injury. This invertebrate model…”
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Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord
Published in Molecular immunology (01-02-2009)“…In vertebrates, central nervous system (CNS) protection is dependent on many immune cells including microglial cells. Indeed, activated microglial cells are…”
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Interaction of Hm C1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis
Published in Journal of neuroinflammation (22-02-2012)“…Background In invertebrates, the medicinal leech is considered to be an interesting and appropriate model to study neuroimmune mechanisms. Indeed, this…”
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A C1q domain containing factor evidenced in the leech nerve cord expressed a chemotactic activity on microglial cells
Published in Molecular immunology (01-10-2008)Get full text
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The Leech Nervous System : A Valuable Model to Study the Microglia Involvement in Regenerative Processes
Published in Clinical & developmental immunology (2013)“…Microglia are intrinsic components of the central nervous system (CNS). During pathologies in mammals, inflammatory processes implicate the resident microglia…”
Get full text
Journal Article