Search Results - "Croom, Hayley A."

Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation by Russ, Brendan E., Olshanksy, Moshe, Smallwood, Heather S., Li, Jasmine, Denton, Alice E., Prier, Julia E., Stock, Angus T., Croom, Hayley A., Cullen, Jolie G., Nguyen, Michelle L.T., Rowe, Stephanie, Olson, Matthew R., Finkelstein, David B., Kelso, Anne, Thomas, Paul G., Speed, Terry P., Rao, Sudha, Turner, Stephen J.

“…The molecular mechanisms that regulate the rapid transcriptional changes that occur during cytotoxic T lymphocyte (CTL) proliferation and differentiation in…”
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Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation by Russ, Brendan E., Olshanksy, Moshe, Smallwood, Heather S., Li, Jasmine, Denton, Alice E., Prier, Julia E., Stock, Angus T., Croom, Hayley A., Cullen, Jolie G., Nguyen, Michelle L.T., Rowe, Stephanie, Olson, Matthew R., Finkelstein, David B., Kelso, Anne, Thomas, Paul G., Speed, Terry P., Rao, Sudha, Turner, Stephen J.

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A Role of Influenza Virus Exposure History in Determining Pandemic Susceptibility and CD8+ T Cell Responses by Quiñones-Parra, Sergio M, Clemens, E Bridie, Wang, Zhongfang, Croom, Hayley A, Kedzierski, Lukasz, McVernon, Jodie, Vijaykrishna, Dhanasekaran, Kedzierska, Katherine

“…Novel influenza viruses often cause differential infection patterns across different age groups, an effect that is defined as heterogeneous demographic…”
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Memory precursor phenotype of CD8+ T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection by Croom, Hayley A., Denton, Alice E., Valkenburg, Sophie A., Swan, Natasha G., Olson, Matthew R., Turner, Stephen J., Doherty, Peter C., Kedzierska, Katherine

“…The mechanistic basis of memory T‐cell development is poorly defined. Phenotypic markers that define precursors at effector stages have been characterized for…”
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A Kinase-Dead Allele of Lyn Attenuates Autoimmune Disease Normally Associated with Lyn Deficiency by Verhagen, Anne M, Wallace, Morgan E, Goradia, Ankita, Jones, Sarah A, Croom, Hayley A, Metcalf, Donald, Collinge, Janelle E, Maxwell, Mhairi J, Hibbs, Margaret L, Alexander, Warren S, Hilton, Douglas J, Kile, Benjamin T, Starr, Robyn

“…Lyn kinase, a member of the Src family of tyrosine kinases, functions as both a positive and negative regulator of B cell activation. In the absence of Lyn,…”
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Incidence immunoassay for distinguishing recent from established HIV-1 infection in therapy-naive populations by WILSON, Kim M, JOHNSON, Elizabeth I. M, CROOM, Hayley A, RICHARDS, Kim M, DOUGHTY, Larissa, CUNNINGHAM, Philip H, KEMP, Bruce E, BRANSON, Bernard M, DAX, Elizabeth M

“…To identify a specific marker of recent HIV-1 infection. The humoral immune response in individuals recently infected with HIV-1 was followed by analysing the…”
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Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFNγ or IL-12 by Dale, C. Jane, De Rose, Robert, Wilson, Kim M., Croom, Hayley A., Thomson, Scott, Coupar, Barbara E.H., Ramsay, Alistair, Purcell, Damian F.J., Ffrench, Rosemary, Law, Matthew, Emery, Sean, Cooper, David A., Ramshaw, Ian A., Boyle, David B., Kent, Stephen J.

“…Induction of HIV-specific T-cell responses by vaccines may facilitate efficient control of HIV. Plasmid DNA vaccines and recombinant fowlpoxvirus (rFPV)…”
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Commercial enzyme immunoassay adapted for the detection of antibodies to hepatitis C virus in dried blood spots by Croom, Hayley A., Richards, Kim M., Best, Susan J., Francis, Barbara H., Johnson, Elizabeth I.M., Dax, Elizabeth M., Wilson, Kim M.

“…Dried blood spots (DBS) provide a convenient method for blood sample collection in many settings where the prevalence of infection with hepatitis C virus (HCV)…”
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Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3 by Croom, Hayley A., Izon, David J., Chong, Mark M., Curtis, David J., Roberts, Andrew W., Kay, Thomas W.H., Hilton, Douglas J., Alexander, Warren S., Starr, Robyn

“…Cytokine signals are central to the differentiation of thymocytes and their stepwise progression through defined developmental stages. The intensity and…”
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Fixing an irrelevant TCRα chain reveals the importance of TCRβ diversity for optimal TCRαβ pairing and function of virus‐specific CD8+ T cells by Valkenburg, Sophie A., Day, E. Bridie, Swan, Natasha G., Croom, Hayley A., Carbone, Francis R., Doherty, Peter C., Turner, Stephen J., Kedzierska, Katherine

“…TCR repertoire diversity can influence the efficacy of CD8+ T‐cell populations, with greater breadth eliciting better protection. We analyzed TCRβ diversity…”
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Mapping histone methylation dynamics during virus-specific CD8+ T cell differentiation in response to infection by Russ, Brendan E., Olshanksy, Moshe, Smallwood, Heather S., Li, Jasmine, Denton, Alice E., Prier, Julia E., Stock, Angus T., Croom, Hayley A., Cullen, Jolie G., Nguyen, Michelle L. T., Rowe, Stephanie, Olson, Matthew R., Finkelstein, David B., Kelso, Anne, Thomas, Paul G., Speed, Terry P., Rao, Sudha, Turner, Stephen J.

“…The molecular mechanisms that regulate the rapid transcriptional changes that occur during cytotoxic T lymphocyte (CTL) proliferation and differentiation in…”
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Memory precursor phenotype of CD8 super(+) T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection by Croom, Hayley A, Denton, Alice E, Valkenburg, Sophie A, Swan, Natasha G, Olson, Matthew R, Turner, Stephen J, Doherty, Peter C, Kedzierska, Katherine

“…The mechanistic basis of memory T-cell development is poorly defined. Phenotypic markers that define precursors at effector stages have been characterized for…”
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Fixing an irrelevant TCR[alpha] chain reveals the importance of TCR[beta] diversity for optimal TCR[alpha][beta] pairing and function of virus-specific CD8+ T cells by Valkenburg, Sophie A, Day, E Bridie, Swan, Natasha G, Croom, Hayley A, Carbone, Francis R, Doherty, Peter C, Turner, Stephen J, Kedzierska, Katherine

“…TCR repertoire diversity can influence the efficacy of CD8+ T-cell populations, with greater breadth eliciting better protection. We analyzed TCR[beta]…”
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Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8 super(+) T cells by Valkenburg, Sophie A, Day, EBridie, Swan, Natasha G, Croom, Hayley A, Carbone, Francis R, Doherty, Peter C, Turner, Stephen J, Kedzierska, Katherine

“…TCR repertoire diversity can influence the efficacy of CD8 super(+) T-cell populations, with greater breadth eliciting better protection. We analyzed TCR beta…”
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Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8+ T cells by Valkenburg, Sophie A, Day, E Bridie, Swan, Natasha G, Croom, Hayley A, Carbone, Francis R, Doherty, Peter C, Turner, Stephen J, Kedzierska, Katherine

“…TCR repertoire diversity can influence the efficacy of CD8(+) T-cell populations, with greater breadth eliciting better protection. We analyzed TCR beta…”
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Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFNgamma or IL-12 by Dale, C Jane, De Rose, Robert, Wilson, Kim M, Croom, Hayley A, Thomson, Scott, Coupar, Barbara E H, Ramsay, Alistair, Purcell, Damian F J, Ffrench, Rosemary, Law, Matthew, Emery, Sean, Cooper, David A, Ramshaw, Ian A, Boyle, David B, Kent, Stephen J

“…Induction of HIV-specific T-cell responses by vaccines may facilitate efficient control of HIV. Plasmid DNA vaccines and recombinant fowlpoxvirus (rFPV)…”
Get full text

Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFN? or IL-12 by DALE, C, DEROSE, R, WILSON, K, CROOM, H, THOMSON, S, COUPAR, B, RAMSAY, A, PURCELL, D, FFRENCH, R, LAW, M

“…Induction of HIV-specific T-cell responses by vaccines may facilitate efficient control of HIV. Plasmid DNA vaccines and recombinant fowlpoxvirus (rFPV)…”
Get full text