Search Results - "Crooks, P."

Asphyxia-activated corticocardiac signaling accelerates onset of cardiac arrest by Li, Duan, Mabrouk, Omar S., Liu, Tiecheng, Tian, Fangyun, Xu, Gang, Rengifo, Santiago, Choi, Sarah J., Mathur, Abhay, Crooks, Charles P., Kennedy, Robert T., Wang, Michael M., Ghanbari, Hamid, Borjigin, Jimo

“…The mechanism by which the healthy heart and brain die rapidly in the absence of oxygen is not well understood. We performed continuous electrocardiography and…”
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Microparticle surface modifications targeting dendritic cells for non-activating applications by Lewis, Jamal S, Zaveri, Toral D, Crooks, Charles P, Keselowsky, Benjamin G

“…Abstract Microparticulate systems for delivery of therapeutics to DCs for immunotherapy have gained attention recently. However, reports addressing the…”
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Targeting NPM1 for the Radiosensitization of Non-Small Cell Lung Cancer by Ofori, M, Sekhar, K, Crooks, P, Penthala, N, Freeman, M.L

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Targeting ENOX1 Impairs Repair of DNA DSBs in Endothelial Cells and Increases Survival of Tumor-Bearing Mice by Smith, C.A, Sekhar, K, Crooks, P, Traver, G.L, Freeman, M.L

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Transarterial chemoembolization with parthenolide in a rat liver tumor model induces tumor regression without any detectable liver or systemic toxicity by Chen, Z, Crooks, P, Borrelli, M

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The impact of HLA class I and EBV latency‐II antigen‐specific CD8+ T cells on the pathogenesis of EBV+ Hodgkin lymphoma by Jones, K., Wockner, L., Brennan, R. M., Keane, C., Chattopadhyay, P. K., Roederer, M., Price, D. A., Cole, D. K., Hassan, B., Beck, K., Gottlieb, D., Ritchie, D. S., Seymour, J. F., Vari, F., Crooks, P., Burrows, S. R., Gandhi, M. K.

“…Summary In 40% of cases of classical Hodgkin lymphoma (cHL), Epstein–Barr virus (EBV) latency‐II antigens [EBV nuclear antigen 1 (EBNA1)/latent membrane…”
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NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT by Nakshatri, H, Appaiah, H N, Anjanappa, M, Gilley, D, Tanaka, H, Badve, S, Crooks, P A, Mathews, W, Sweeney, C, Bhat-Nakshatri, P

“…The transcription factor nuclear factor-kappaB (NF- κ B) is constitutively active in several cancers and is a target of therapeutic development. We recently…”
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A Comprehensive Analysis of the Cellular and EBV‐Specific MicroRNAome in Primary CNS PTLD Identifies Different Patterns Among EBV‐Associated Tumors by Fink, S. E. K., Gandhi, M. K., Nourse, J. P., Keane, C., Jones, K., Crooks, P., Jöhrens, K., Korfel, A., Schmidt, H., Neumann, S., Tiede, A., Jäger, U., Dührsen, U., Neuhaus, R., Dreyling, M., Borchert, K., Südhoff, T., Riess, H., Anagnostopoulos, I., Trappe, R. U.

“…Primary central nervous system (pCNS) posttransplant lymphoproliferative disorder (PTLD) is a complication of solid organ transplantation characterized by poor…”
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Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma by Keane, C., Nourse, J. P., Crooks, P., Nguyen-Van, D., Mutsando, H., Mollee, P., Lea, R. A., Gandhi, M. K.

“…Background Recent reports suggest genetic polymorphisms influence susceptibility to rituximab‐induced late‐onset neutropenia (LON), which in turn may be a…”
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The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L by Worthen, D R, Ghosheh, O A, Crooks, P A

“…A crude gum, a fixed oil and two purified components of Nigella sativa seed, thymoquinone (TQ) and dithymoquinone (DIM), were assayed in vitro for their…”
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Nornicotine is self-administered intravenously by rats by BARDO, M. T, GREEN, T. A, CROOKS, P. A, DWOSKIN, L. P

“…Nicotine is a tobacco alkaloid known to be important in the acquisition and maintenance of tobacco smoking. However, other constituents in tobacco may…”
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In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche by Zong, H, Sen, S, Zhang, G, Mu, C, Albayati, Z F, Gorenstein, D G, Liu, X, Ferrari, M, Crooks, P A, Roboz, G J, Shen, H, Guzman, M L

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Effects of norketamine enantiomers in rodent models of persistent pain by Holtman, Joseph R., Crooks, Peter A., Johnson-Hardy, Jaime K., Hojomat, Marhaba, Kleven, Mark, Wala, Elzbieta P.

“…NMDA-receptor antagonists are potential drugs for chronic pain treatment, in particular for neuropathic pain involving central sensitization processes…”
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Scientific overview: 2013 BBC plenary symposium on tobacco addiction by De Biasi, M, McLaughlin, I, Perez, E.E, Crooks, P.A, Dwoskin, L.P, Bardo, M.T, Pentel, P.R, Hatsukami, D

“…Abstract Nicotine dependence plays a critical role in addiction to tobacco products, and thus contributes to a variety of devastating tobacco-related diseases…”
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High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed ( Nigella sativa L.) by Ghosheh, Omar A., Houdi, Abdulghani A., Crooks, Peter A.

“…An HPLC method for quantifying the putative pharmacologically active constituents: thymoquinone (TQ), dithymoquinone (DTQ), thymohydroquinone (THQ), and thymol…”
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Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats by Neugebauer, N M, Zhang, Z, Crooks, P A, Dwoskin, L P, Bardo, M T

“…Recent work has shown that the novel compound N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) may selectively block nicotinic acetylcholine…”
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Region‐specific effects of N,N′‐dodecane‐1,12‐diyl‐bis‐3‐picolinium dibromide on nicotine‐induced increase in extracellular dopamine in vivo by Rahman, S, Zhang, Z, Papke, R L, Crooks, P A, Dwoskin, L P, Bardo, M T

“…Background and purpose: Systemic administration of N,N′‐dodecane‐1,12‐diyl‐bis‐3‐picolinium dibromide (bPiDDB), an antagonist of nicotinic acetylcholine…”
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Lobeline Displaces [3H]Dihydrotetrabenazine Binding and Releases [3H]Dopamine from Rat Striatal Synaptic Vesicles: Comparison with d‐Amphetamine by Teng, LiHong, Crooks, Peter A., Dwoskin, Linda P.

“…: Lobeline, an alkaloid from Indian tobacco (Lobelia inflata), is classified as a nicotinic agonist and is currently used as a smoking cessation agent…”
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Interaction between morphine and norketamine enantiomers in rodent models of nociception by Holtman, Joseph R., Crooks, Peter A., Johnson-Hardy, Jaime, Wala, Elzbieta P.

“…Ketamine, one of a few clinically-available N-Methyl-D-aspartate (NMDA)-receptor antagonists, is known to improve the analgesic efficacy of opioids in humans…”
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Residence Times and Half-Lives of Nicotine Metabolites in Rat Brain after Acute Peripheral Administration of [2′-14C]Nicotine by GHOSHEH, O, DWOSKIN, L. P, LI, W.-K, CROOKS, P. A

“…The residence times of nicotine and its metabolites in rat brain after acute peripheral nicotine administration were determined. We hypothesize that nicotine…”
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