Search Results - "Crooke, Helen"

Classical swine fever virus: the past, present and future by Ganges, Llilianne, Crooke, Helen R., Bohórquez, Jose Alejandro, Postel, Alexander, Sakoda, Yoshihiro, Becher, Paul, Ruggli, Nicolas

“…•A comprehensive overview of the recent advances in fundamental CSFV research.•Recent advances in diagnostics and vaccine development.•Genetic diversity of…”
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Development and validation of a multiplex, real-time RT PCR assay for the simultaneous detection of classical and African swine fever viruses by Haines, Felicity J, Hofmann, Martin A, King, Donald P, Drew, Trevor W, Crooke, Helen R

“…A single-step, multiplex, real-time polymerase chain reaction (RT-PCR) was developed for the simultaneous and differential laboratory diagnosis of Classical…”
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Challenge of pigs with classical swine fever viruses after C-strain vaccination reveals remarkably rapid protection and insights into early immunity by Graham, Simon P, Everett, Helen E, Haines, Felicity J, Johns, Helen L, Sosan, Olubukola A, Salguero, Francisco J, Clifford, Derek J, Steinbach, Falko, Drew, Trevor W, Crooke, Helen R

“…Pre-emptive culling is becoming increasingly questioned as a means of controlling animal diseases, including classical swine fever (CSF). This has prompted…”
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Activation of Dendritic Cells in Tonsils Is Associated with CD8 T Cell Responses following Vaccination with Live Attenuated Classical Swine Fever Virus by Soldevila, Ferran, Edwards, Jane C., Graham, Simon P., Crooke, Helen R., Werling, Dirk, Steinbach, Falko

“…Classical swine fever (CSF) is a highly contagious disease caused by the classical swine fever virus (CSFV). The live attenuated C-strain vaccine is highly…”
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Molecular Epidemiology Questions Transmission Pathways Identified During the Year 2000 Outbreak of Classical Swine Fever in the UK by Strong, Rebecca, McCleary, Stephen, Grierson, Sylvia, Choudhury, Bhudipa, Steinbach, Falko, Crooke, Helen R.

“…The last outbreak of classical swine fever (CSF) in the UK occurred in 2000. A total of 16 domestic pig holdings in the East Anglia region were confirmed as…”
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African Swine Fever: Disease Dynamics in Wild Boar Experimentally Infected with ASFV Isolates Belonging to Genotype I and II by Sánchez-Cordón, Pedro J., Nunez, Alejandro, Neimanis, Aleksija, Wikström-Lassa, Emil, Montoya, María, Crooke, Helen, Gavier-Widén, Dolores

“…After the re-introduction of African swine fever virus (ASFV) genotype II isolates into Georgia in 2007, the disease spread from Eastern to Western Europe and…”
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Head Start Immunity: Characterizing the Early Protection of C Strain Vaccine Against Subsequent Classical Swine Fever Virus Infection by McCarthy, Ronan R, Everett, Helen E, Graham, Simon P, Steinbach, Falko, Crooke, Helen R

“…Classical Swine Fever Virus (CSFV) is an ongoing threat to the pig industry due to the high transmission and mortality rates associated with infection. Live…”
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Substitution of warthog NF-κB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus by McCleary, Stephen, Strong, Rebecca, McCarthy, Ronan R., Edwards, Jane C., Howes, Emma L., Stevens, Lisa M., Sánchez-Cordón, Pedro J., Núñez, Alejandro, Watson, Samantha, Mileham, Alan J., Lillico, Simon G., Tait-Burkard, Christine, Proudfoot, Chris, Ballantyne, Maeve, Whitelaw, C. Bruce A., Steinbach, Falko, Crooke, Helen R.

“…African swine fever virus (ASFV) causes a lethal, haemorrhagic disease in domestic swine that threatens pig production across the globe. Unlike domestic pigs,…”
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Comparative evaluation of disease dynamics in wild boar and domestic pigs experimentally inoculated intranasally with the European highly virulent African swine fever virus genotype II strain "Armenia 2007" by Sánchez-Cordón, Pedro J, Lean, Fabian Z X, Batten, Carrie, Steinbach, Falko, Neimanis, Aleksija, Le Potier, Marie-Frédérique, Wikström-Lassa, Emil, Wynne, Felicity, Strong, Rebecca, McCleary, Stephen, Crooke, Helen, Gavier-Widén, Dolores, Núñez, Alejandro

“…Since the reintroduction of African swine fever virus (ASFV) in Europe in 2007 and its subsequent spread to Asia, wild boar has played a crucial role in…”
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Identification of neutralizing epitopes on the D/A domain of the E2 glycoprotein of classical swine fever virus by Huang, Yu-Liang, Meyer, Denise, Postel, Alexander, Tsai, Kuo-Jung, Liu, Hsin-Meng, Yang, Chia-Huei, Huang, Yu-Chun, Chang, Hui-Wen, Deng, Ming-Chung, Wang, Fun-In, Becher, Paul, Crooke, Helen, Chang, Chia-Yi

“…•CSFV-specific epitopes, the target of neutralizing antibodies, are identified on the D/A domain of E2 protein.•Epitopes 780–794, 810–824, and 846–850 likely…”
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Characterization of the Myeloid Cell Populations' Resident in the Porcine Palatine Tonsil by Soldevila, Ferran, Edwards, Jane C, Graham, Simon P, Stevens, Lisa M, Crudgington, Bentley, Crooke, Helen R, Werling, Dirk, Steinbach, Falko

“…The palatine tonsil is the portal of entry for food and air and is continuously subjected to environmental challenges, including pathogens, which use the…”
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Proteome-wide screening reveals immunodominance in the CD8 T cell response against classical swine fever virus with antigen-specificity dependent on MHC class I haplotype expression by Franzoni, Giulia, Kurkure, Nitin V, Essler, Sabine E, Pedrera, Miriam, Everett, Helen E, Bodman-Smith, Kikki B, Crooke, Helen R, Graham, Simon P

“…Vaccination with live attenuated classical swine fever virus (CSFV) vaccines induces a rapid onset of protection which has been associated with virus-specific…”
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CD1− and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets by Edwards, Jane C., Everett, Helen E., Pedrera, Miriam, Mokhtar, Helen, Marchi, Emanuele, Soldevila, Ferran, Kaveh, Daryan A., Hogarth, Philip J., Johns, Helen L., Nunez-Garcia, Javier, Steinbach, Falko, Crooke, Helen R., Graham, Simon P.

“…Conventional dendritic cells (cDC) are professional antigen-presenting cells that induce immune activation or tolerance. Two functionally specialised…”
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Assessment of the Phenotype and Functionality of Porcine CD8 T Cell Responses following Vaccination with Live Attenuated Classical Swine Fever Virus (CSFV) and Virulent CSFV Challenge by Franzoni, Giulia, Kurkure, Nitin V, Edgar, Daniel S, Everett, Helen E, Gerner, Wilhelm, Bodman-Smith, Kikki B, Crooke, Helen R, Graham, Simon P

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification of a Common Conformational Epitope on the Glycoprotein E2 of Classical Swine Fever Virus and Border Disease Virus by Huang, Yu-Liang, Meyer, Denise, Postel, Alexander, Tsai, Kuo-Jung, Liu, Hsin-Meng, Yang, Chia-Huei, Huang, Yu-Chun, Berkley, Nicholas, Deng, Ming-Chung, Wang, Fun-In, Becher, Paul, Crooke, Helen, Chang, Chia-Yi

“…Classical swine fever virus (CSFV) shares high structural and antigenic homology with bovine viral diarrhea virus (BVDV) and border disease virus (BDV)…”
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Evaluation of Lesions and Viral Antigen Distribution in Domestic Pigs Inoculated Intranasally with African Swine Fever Virus Ken05/Tk1 (Genotype X) by Sánchez-Cordón, Pedro J, Floyd, Tobias, Hicks, Daniel, Crooke, Helen R, McCleary, Stephen, McCarthy, Ronan R, Strong, Rebecca, Dixon, Linda K, Neimanis, Aleksija, Wikström-Lassa, Emil, Gavier-Widén, Dolores, Núñez, Alejandro

“…The understanding of the pathogenic mechanisms and the clinicopathological forms caused by currently circulating African swine fever virus (ASFV) isolates is…”
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Characterisation of vaccine-induced, broadly cross-reactive IFN-γ secreting T cell responses that correlate with rapid protection against classical swine fever virus by Graham, Simon P, Haines, Felicity J, Johns, Helen L, Sosan, Olubukola, La Rocca, S. Anna, Lamp, Benjamin, Rümenapf, Till, Everett, Helen E, Crooke, Helen R

“…Highlights ► Vaccine-induced T cell IFN-γ responses show broad reactivity against CSFV strains. ► T cell epitopes are conserved between CSF and BVD viruses. ►…”
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Factors affecting the infectivity of tissues from pigs with classical swine fever: Thermal inactivation rates and oral infectious dose by Cowan, Lucie, Haines, Felicity J., Everett, Helen E., Crudgington, Bentley, Johns, Helen L., Clifford, Derek, Drew, Trevor W., Crooke, Helen R.

“…•Thermal inactivation rates of CSFV in meat tissues have been determined.•D and Z values allow estimation of thermal inactivation times at any…”
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Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions by Meek, Stephen, Watson, Tom, Eory, Lel, McFarlane, Gus, Wynne, Felicity J, McCleary, Stephen, Dunn, Laura E M, Charlton, Emily M, Craig, Chloe, Shih, Barbara, Regan, Tim, Taylor, Ryan, Sutherland, Linda, Gossner, Anton, Chintoan-Uta, Cosmin, Fletcher, Sarah, Beard, Philippa M, Hassan, Musa A, Grey, Finn, Hope, Jayne C, Stevens, Mark P, Nowak-Imialek, Monika, Niemann, Heiner, Ross, Pablo J, Tait-Burkard, Christine, Brown, Sarah M, Lefevre, Lucas, Thomson, Gerard, McColl, Barry W, Lawrence, Alistair B, Archibald, Alan L, Steinbach, Falko, Crooke, Helen R, Gao, Xuefei, Liu, Pentao, Burdon, Tom

“…Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune…”
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Partial Activation of Natural Killer and gamma delta T Cells by Classical Swine Fever Viruses Is Associated with Type I Interferon Elicited from Plasmacytoid Dendritic Cells by Franzoni, Giulia, Edwards, Jane C, Kurkure, Nitin V, Edgar, Daniel S, Sanchez-Cordon, Pedro J, Haines, Felicity J, Salguero, Francisco J, Everett, Helen E, Bodman-Smith, Kikki B, Crooke, Helen R

“…Vaccination with live attenuated classical swine fever virus (CSFV) vaccines can rapidly confer protection in the absence of neutralizing antibodies. With an…”
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