Search Results - "Crook, Richard J.P"

Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration by Adams, Stephanie J, Crook, Richard J.P, DeTure, Michael, Randle, Suzanne J, Innes, Amy E, Yu, Xin Z, Lin, Wen-Lang, Dugger, Brittany N, McBride, Melinda, Hutton, Mike, Dickson, Dennis W, McGowan, Eileen

“…Here, we describe the generation and characterization of a novel tau transgenic mouse model (mTau) that overexpresses wild-type murine tau protein by twofold…”
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Pathogenicity of exonic indels in fused in sarcoma in amyotrophic lateral sclerosis by Rutherford, Nicola J, Finch, Nicole A, DeJesus-Hernandez, Mariely, Crook, Richard J.P, Lomen-Hoerth, Catherine, Wszolek, Zbigniew K, Uitti, Ryan J, Graff-Radford, Neill R, Rademakers, Rosa

“…Abstract Insertion and deletion variants (indels) within poly glycine tracts of fused in sarcoma (FUS) were initially reported as causative of disease in…”
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Use of a wild-type tauopathy model to generate a novel Alzheimer model by Adams, Stephanie J, Crook, Richard J.P, McBride, Melinda, Dickson, Dennis W

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P2-172: Wild-type mouse tau transgenic model: Halfway to a complete AD model by Adams, Stephanie J, Dugger, Brittany, Innes, Amy, Randle, Suzanne J, Yu, Cindy, Crook, Richard J.P, Hutton, Mike, McGowan, Eileen, Dickson, Dennis W

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Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis by Rutherford, Nicola J, Zhang, Yong-Jie, Baker, Matt, Gass, Jennifer M, Finch, Nicole A, Xu, Ya-Fei, Stewart, Heather, Kelley, Brendan J, Kuntz, Karen, Crook, Richard J P, Sreedharan, Jemeen, Vance, Caroline, Sorenson, Eric, Lippa, Carol, Bigio, Eileen H, Geschwind, Daniel H, Knopman, David S, Mitsumoto, Hiroshi, Petersen, Ronald C, Cashman, Neil R, Hutton, Mike, Shaw, Christopher E, Boylan, Kevin B, Boeve, Bradley, Graff-Radford, Neill R, Wszolek, Zbigniew K, Caselli, Richard J, Dickson, Dennis W, Mackenzie, Ian R, Petrucelli, Leonard, Rademakers, Rosa

“…The TAR DNA-binding protein 43 (TDP-43) has been identified as the major disease protein in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar…”
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P4‐047: Use of a wild‐type tauopathy model to generate a novel Alzheimer model by Adams, Stephanie J., Crook, Richard J.P., McBride, Melinda, Dickson, Dennis W.

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The Ischemic Stroke Genetics Study (ISGS) Protocol by Meschia, James F, Brott, Thomas G, Brown, Jr, Robert D, Crook, Richard J P, Frankel, Michael, Hardy, John, Merino, José G, Rich, Stephen S, Silliman, Scott, Worrall, Bradford Burke

“…The molecular basis for the genetic risk of ischemic stroke is likely to be multigenic and influenced by environmental factors. Several small case-control…”
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Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD by Myers, Amanda J., Marshall, Helen, Holmans, Peter, Compton, Danielle, Crook, Richard J.P., Mander, Adrian P., Nowotny, Petra, Smemo, Scott, Dunstan, Melanie, Jehu, Luke, Wang, Jen C., Hamshere, Marian, Morris, John C., Norton, Joanne, Chakraventy, Sumi, Tunstall, Nigel, Lovestone, Simon, Petersen, Ronald, O'Donovan, Michael, Jones, Lesley, Williams, Julie, Owen, Michael J., Hardy, John, Goate, Alison

“…Linkage studies indicate that the same region of chromosome 10 contains a risk locus for late onset Alzheimer disease (LOAD) and a QTL for plasma Aβ42 levels…”
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