Search Results - "Cronin, Chunxia G"

Deletion of the P2X4 receptor is neuroprotective acutely, but induces a depressive phenotype during recovery from ischemic stroke by Verma, Rajkumar, Cronin, Chunxia G., Hudobenko, Jacob, Venna, Venugopal R., McCullough, Louise D., Liang, Bruce T.

“…•Purinergic receptors P2X4 are upregulated after stroke.•P2X4Rs are highly expressed on myeloid cells.•P2X4Rs participate in microglial activation after…”
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Revealing the Novel Role of Purinergic Receptor P2X4 in Phagocytic Uptake After Ischemic Stroke by Gamiotea-Turro, Daylin, Cronin, Chunxia G, Yadav, Sanjeev Kumar, Yadawa, Arun Kumar, Cormier, Mary-Katherine, Liang, Bruce T, Verma, Rajkumar

“…Purinergic receptor P2X4 (P2X4R), highly expressed on microglia and macrophages, is activated by ATP released from damaged cells and linked to poststroke…”
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Neuroprotective and neuro-rehabilitative effects of acute purinergic receptor P2X4 (P2X4R) blockade after ischemic stroke by Srivastava, Pranay, Cronin, Chunxia G., Scranton, Victoria L., Jacobson, Kenneth A., Liang, Bruce T., Verma, Rajkumar

“…Stroke remains a leading cause of disability in the United States. Despite recent advances, interventions to reduce damage and enhance recovery after stroke…”
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PLCβ2 Promotes VEGF-Induced Vascular Permeability by Phoenix, Kathryn N., Yue, Zhichao, Yue, Lixia, Cronin, Chunxia G., Liang, Bruce T., Hoeppner, Luke H., Claffey, Kevin P.

“…BACKGROUNDRegulation of vascular permeability is critical to maintaining tissue metabolic homeostasis. VEGF (vascular endothelial growth factor) is a key…”
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Nexinhib20 Inhibits Neutrophil Adhesion and β2 Integrin Activation by Antagonizing Rac-1–Guanosine 5′-Triphosphate Interaction by Liu, Wei, Cronin, Chunxia G., Cao, Ziming, Wang, Chengliang, Ruan, Jianbin, Pulikkot, Sunitha, Hall, Alexxus, Sun, Hao, Groisman, Alex, Chen, Yunfeng, Vella, Anthony T., Hu, Liang, Liang, Bruce T., Fan, Zhichao

“…Neutrophils are critical for mediating inflammatory responses. Inhibiting neutrophil recruitment is an attractive approach for preventing inflammatory…”
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Nexinhib20 prevents myocardial ischemia‐reperfusion injury by inhibiting neutrophil adhesion and β2 integrin activation by Fan, Zhichao, Liu, Wei, Cronin, Chunxia G., Wang, Chengliang, Ruan, Jianbin, Johnson, Jennifer L., Catz, Sergio, Sun, Hao, Groisman, Alex, Chen, Yunfeng, Hu, Liang, Vella, Anthony T., Liang, Bruce

“…Primary percutaneous coronary intervention (PPCI)—a therapy intended to restore blood flow after acute myocardial infarction—can also induce myocardial…”
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Sex-specific and immune-cell-specific contributions of CD18 in myocardial ischemia-reperfusion injury by Fan, Zhichao, Liu, Wei, Cronin, Chunxia G, Wen, Lai, Ley, Klaus, Liang, Bruce T

“…Leukocyte recruitment and their mediated inflammatory responses are critical for cardiovascular diseases, including myocardial ischemia-reperfusion (I/R)…”
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Phospholipase Cβ2 Promotes Vascular Endothelial Growth Factor Induced Vascular Permeability by Phoenix, Kathryn N., Yue, Zhichao, Yue, Lixia, Cronin, Chunxia G., Liang, Bruce T., Hoeppner, Luke H., Claffey, Kevin P.

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PLC (Phospholipase C) β2 Promotes VEGF (Vascular Endothelial Growth Factor)–Induced Vascular Permeability by Phoenix, Kathryn N., Yue, Zhichao, Yue, Lixia, Cronin, Chunxia G., Liang, Bruce T., Hoeppner, Luke H., Claffey, Kevin P.

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Abstract WP143: Acute Treatment With Purinergic Receptor P2X4 Inhibitors Show Neuroprotective and Neuro-Rehabilitation Potential in Ischemic Stroke by Verma, Rajkumar, Srivastava, Pranay, Cronin, Chunxia G, Scranton, Victoria, Jacobson, Kenneth A, Liang, Bruce T

“…Abstract only Introduction: Stroke remains a leading cause of disability in the United States. Despite recent advances, interventions to reduce damage and…”
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Nexinhib20 inhibits neutrophil adhesion and β2 integrin activation by antagonizing Rac-1-GTP interaction by Liu, Wei, Cronin, Chunxia G, Cao, Ziming, Wang, Chengliang, Ruan, Jianbin, Pulikkot, Sunitha, Hall, Alexxus, Sun, Hao, Groisman, Alex, Chen, Yunfeng, Vella, Anthony T., Hu, Liang, Liang, Bruce T., Fan, Zhichao

“…Neutrophils are critical for mediating inflammatory responses. Inhibiting neutrophil recruitment is an attractive approach for preventing inflammatory…”
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Nexinhib20 inhibits neutrophil adhesion and β2 integrin activation to prevent myocardial ischemia-reperfusion injury by Fan, Zhichao, Liu, Wei, Cronin, Chunxia G, Wang, Chengliang, Ruan, Jianbin, Johnson, Jennifer L, Catz, Sergio, Sun, Hao, Groisman, Alex, Chen, Yunfeng, Hu, Liang, Vella, Anthony T, Liang, Bruce

“…Primary percutaneous coronary intervention (PPCI)—a therapy intended to restore blood flow after acute myocardial infarction—can also induce myocardial…”
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Two alanines juxtaposed to aggrecan's G1 domain alter its intracellular localization by Oliver, Bonnie L., Cronin, Chunxia G., Bue, Catherine, Hand, Arthur R., Tanzer, Marvin L.

“…Nascent proteins translated and processed in the endoplasmic reticulum (ER) sometimes contain intrinsic signals for ER retention or ER retrieval. These signals…”
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Divergent stress responses to IL-1β, nitric oxide, and tunicamycin by chondrocytes by Oliver, Bonnie L., Cronin, Chunxia G., Zhang-Benoit, Yahui, Goldring, Mary B., Tanzer, Marvin L.

“…As the only cell in cartilage responsible for matrix synthesis, the chondrocyte's viability is crucial to healthy tissue. It must tolerate stresses from both…”
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Divergent stress responses to IL-1beta, nitric oxide, and tunicamycin by chondrocytes by Oliver, Bonnie L, Cronin, Chunxia G, Zhang-Benoit, Yahui, Goldring, Mary B, Tanzer, Marvin L

“…As the only cell in cartilage responsible for matrix synthesis, the chondrocyte's viability is crucial to healthy tissue. It must tolerate stresses from both…”
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