Search Results - "Cromarty, A. Duncan"
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Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays
Published in BMC research notes (20-02-2015)“…The tetrazolium-based MTT assay has long been regarded as the gold standard of cytotoxicity assays as it is highly sensitive and has been miniaturised for use…”
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Quantitative plasma analysis using automated online solid-phase extraction with column switching LC-MS/MS for characterising cytochrome P450 2D6 and 2C19 metabolism
Published in Journal of separation science (01-05-2011)“…In this study an easy and efficient assay for simultaneous quantitation of plasma concentrations of probe drugs and their metabolically relevant metabolites…”
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Evaluation of predictive CYP2C19 genotyping assays relative to measured phenotype in a South African cohort
Published in Pharmacogenomics (01-08-2015)“…To align predicted and measured CYP2C19 phenotype in a South African cohort. Genotyping of CYP2C19*2, *3, *9, *15, *17, *27 and *28 was performed using…”
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The antioxidant potential of Sutherlandia frutescens
Published in Journal of ethnopharmacology (01-11-2004)“…One of the best-known multi-purpose medicinal plants in Southern Africa, Sutherlandia frutescens subsp. microphylla (family: Fabaceae/Leguminosa), is used for…”
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Journal Article -
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Limitations of the 3- assay when compared to three commonly used cell enumeration assays
Published in BMC research notes (20-02-2015)“…The tetrazolium-based MTT assay has long been regarded as the gold standard of cytotoxicity assays as it is highly sensitive and has been miniaturised for use…”
Get full text
Journal Article -
6
Evaluation of predictive
Published in Pharmacogenomics (01-08-2015)“…To align predicted and measured CYP2C19 phenotype in a South African cohort. Genotyping of and was performed using PCR-RFLP, and an activity score (AS) system…”
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