Search Results - "Crola Da Silva, C"
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Protection of Human Pancreatic Islets from Lipotoxicity by Modulation of the Translocon
Published in PloS one (10-02-2016)“…Type 2 diabetes is characterized by peripheral insulin resistance and pancreatic beta cell dysfunction. Elevated free fatty acids (FFAs) may impair beta cell…”
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The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury
Published in Cell death and differentiation (01-02-2016)“…Glycogen synthase kinase-3 β (GSK3 β ) is a multifunctional kinase whose inhibition is known to limit myocardial ischemia–reperfusion injury. However, the…”
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Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D
Published in Journal of molecular and cellular cardiology (01-07-2015)“…Abstract Rationale . How ischemic postconditioning can inhibit opening of the mitochondrial permeability transition pore (PTP) and subsequent cardiac myocytes…”
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The influence of early post-STEMI inflammation on diastolic function: diagnostic and therapeutic implications
Published in European heart journal (09-11-2023)“…Abstract Introduction We know that diastolic dysfunction (DD) after ST elevation myocardial infarction (STEMI) is associated with patients prognosis. Systolic…”
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Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion
Published in Cell death & disease (19-08-2020)“…The mitochondrial permeability transition pore (mPTP) plays a critical role in the pathogenesis of cardiovascular diseases, including ischemia/reperfusion…”
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Matrix Metalloproteinase-9 and Monocyte Chemoattractant Protein-1 Are Associated With Collateral Status in Acute Ischemic Stroke With Large Vessel Occlusion
Published in Stroke (1970) (01-07-2020)“…BACKGROUND AND PURPOSE:In ischemic stroke, inflammatory status may condition the development of collateral circulation. Here we assessed the relationship…”
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Impact of Age on Systemic Inflammatory Profile of Patients With ST-Segment–Elevation Myocardial Infarction and Acute Ischemic Stroke
Published in Stroke (1970) (01-07-2022)“…Aging is associated with a chronic low-grade inflammatory state. This condition may affect the acute inflammatory response involved in ST-segment-elevation…”
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Heat Shock Protein 70 as a Biomarker of Clinical Outcomes After STEMI
Published in Journal of the American College of Cardiology (07-01-2020)“…From 2016 to 2018, we prospectively enrolled in our hospital 251 consecutive patients with STEMI who underwent percutaneous coronary intervention (PCI)…”
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IL-10 / IL-6 serum ratio as a prognosis marker of STEMI
Published in European heart journal (01-11-2020)“…Abstract Introduction IL-6 and IL-10 are two major cytokines secreted at the acute phase of myocardial infarction (MI). IL-6 has a pro-inflammatory effect…”
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Colchicine effect on inflammation biomarkers in acute myocardial infarction
Published in Archives of cardiovascular diseases (01-01-2024)Get full text
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Inflammatory profile and white matter hyperintensity burden in acute ischemic stroke patients
Published in Journal of neuroimmunology (15-10-2022)“…Inflammation is involved in small vessel disease (SVD). We aim to clarify whether inflammation related to white matter hyperintensities (WMH), a key component…”
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Association of myocardial hemorrhage and persistent microvascular obstruction with circulating inflammatory biomarkers in STEMI patients
Published in PloS one (28-01-2021)“…Myocardial hemorrhage (IMH) and persistent microvascular obstruction (MVO) are associated with impaired myocardial recovery and adverse clinical outcomes in…”
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Treatment of hypoxia‐dependent cardiovascular diseases by myo‐inositol trispyrophosphate (ITPP)‐enhancement of oxygen delivery by red blood cells
Published in Journal of cellular and molecular medicine (01-02-2020)“…Heart failure is a consequence of progression hypoxia‐dependent tissue damages. Therapeutic approaches to restore and/or protect the healthy cardiac tissue…”
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P1681Daytime variation of infarct size in STEMI patients
Published in European heart journal (01-08-2018)Get full text
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Matrix Metalloproteinase-9 Relationship With Infarct Growth and Hemorrhagic Transformation in the Era of Thrombectomy
Published in Frontiers in neurology (09-06-2020)“…Objective: To assess the relationship between matrix metalloproteinase 9 (MMP-9), a proteolytic enzyme involved in the breakdown of the blood-brain barrier,…”
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Myocardial ischemia-reperfusion and diabetes: The crux of animal model choice
Published in Archives of cardiovascular diseases supplements (01-05-2021)Get full text
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Serum Soluble Tumor Necrosis Factor Receptors 1 and 2 Are Early Prognosis Markers After ST-Segment Elevation Myocardial Infarction
Published in Frontiers in pharmacology (01-09-2021)“…Background: As inflammation following ST-segment elevation myocardial infarction (STEMI) is both beneficial and deleterious, there is a need to find new…”
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A lower admission level of interleukin-6 is associated with first-pass effect in ischemic stroke patients
Published in Journal of neurointerventional surgery (01-03-2022)“…First-pass effect (FPE) defined as a complete or near-complete reperfusion achieved after a single thrombectomy pass is predictive of favorable outcome in…”
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The SR/ER-mitochondria calcium crosstalk is regulated by GSK3[beta] during reperfusion injury
Published in Cell death and differentiation (01-02-2016)“…Glycogen synthase kinase-3β (GSK3β) is a multifunctional kinase whose inhibition is known to limit myocardial ischemia-reperfusion injury. However, the…”
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