Search Results - "Croft, Jacob T."

Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice by Mangala Prasad, Vidya, Leaman, Daniel P., Lovendahl, Klaus N., Croft, Jacob T., Benhaim, Mark A., Hodge, Edgar A., Zwick, Michael B., Lee, Kelly K.

“…HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing antibodies. However, Env structure and organization in its native virion…”
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Composition, structure and function of the eukaryotic flagellum distal tip by Croft, Jacob T, Zabeo, Davide, Subramanian, Radhika, Höög, Johanna L

“…Cilia and flagella are long extensions commonly found on the surface of eukaryotic cells. In fact, most human cells have a flagellum, and failure to correctly…”
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SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules by Gui, Miao, Croft, Jacob T, Zabeo, Davide, Acharya, Vajradhar, Kollman, Justin M, Burgoyne, Thomas, Höög, Johanna L, Brown, Alan

“…The cilium-centrosome complex contains triplet, doublet, and singlet microtubules. The lumenal surfaces of each microtubule within this diverse array are…”
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Axonemal doublet microtubules can split into two complete singlets in human sperm flagellum tips by Zabeo, Davide, Croft, Jacob T., Höög, Johanna L.

“…Motile flagella are crucial for human fertility and embryonic development. The distal tip of the flagellum is where growth and intra‐flagellar transport are…”
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Instability in a coiled‐coil signaling helix is conserved for signal transduction in soluble guanylyl cyclase by Weichsel, Andrzej, Kievenaar, Jessica A., Curry, Roslyn, Croft, Jacob T., Montfort, William R.

“…How nitric oxide (NO) activates its primary receptor, α1/β1 soluble guanylyl cyclase (sGC or GC‐1), remains unknown. Likewise, how stimulatory compounds…”
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Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection by Guenthoer, Jamie, Lilly, Michelle, Starr, Tyler N, Dadonaite, Bernadeta, Lovendahl, Klaus N, Croft, Jacob T, Stoddard, Caitlin I, Chohan, Vrasha, Ding, Shilei, Ruiz, Felicitas, Kopp, Mackenzie S, Finzi, Andrés, Bloom, Jesse D, Chu, Helen Y, Lee, Kelly K, Overbaugh, Julie

“…The antiviral benefit of antibodies can be compromised by viral escape especially for rapidly evolving viruses. Therefore, durable, effective antibodies must…”
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Nuclear envelope budding is a response to cellular stress by Panagaki, Dimitra, Croft, Jacob T., Keuenhof, Katharina, Berglund, Lisa Larsson, Andersson, Stefanie, Kohler, Verena, Büttner, Sabrina, Tamás, Markus J., Nyström, Thomas, Neutze, Richard, Höög, Johanna L.

“…Nuclear envelope budding (NEB) is a recently discovered alternative pathway for nucleocytoplasmic communication distinct from the movement of material through…”
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De novo design of monomeric helical bundles for pH‐controlled membrane lysis by Goldbach, Nicolas, Benna, Issa, Wicky, Basile I. M., Croft, Jacob T., Carter, Lauren, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Sankaran, Banumathi, Yang, Erin C., Lee, Kelly K., Baker, David

“…Targeted intracellular delivery via receptor‐mediated endocytosis requires the delivered cargo to escape the endosome to prevent lysosomal degradation. This…”
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