Search Results - "Croft, Gist F"

Self-organization of the in vitro attached human embryo by Deglincerti, Alessia, Croft, Gist F., Pietila, Lauren N., Zernicka-Goetz, Magdalena, Siggia, Eric D., Brivanlou, Ali H.

“…An in vitro model to study the early events that direct human embryo development after formation of the blastocyst and implantation in the uterine wall…”
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Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines by Bock, Christoph, Kiskinis, Evangelos, Verstappen, Griet, Gu, Hongcang, Boulting, Gabriella, Smith, Zachary D., Ziller, Michael, Croft, Gist F., Amoroso, Mackenzie W., Oakley, Derek H., Gnirke, Andreas, Eggan, Kevin, Meissner, Alexander

“…The developmental potential of human pluripotent stem cells suggests that they can produce disease-relevant cell types for biomedical research. However,…”
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Accelerated high-yield generation of limb-innervating motor neurons from human stem cells by Amoroso, Mackenzie W, Croft, Gist F, Williams, Damian J, O'Keeffe, Sean, Carrasco, Monica A, Davis, Anne R, Roybon, Laurent, Oakley, Derek H, Maniatis, Tom, Henderson, Christopher E, Wichterle, Hynek

“…Human pluripotent stem cells are a promising source of differentiated cells for developmental studies, cell transplantation, disease modeling, and drug…”
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A functionally characterized test set of human induced pluripotent stem cells by Wichterle, Hynek, Eggan, Kevin, Boulting, Gabriella L, Kiskinis, Evangelos, Croft, Gist F, Amoroso, Mackenzie W, Oakley, Derek H, Wainger, Brian J, Williams, Damian J, Kahler, David J, Yamaki, Mariko, Davidow, Lance, Rodolfa, Christopher T, Dimos, John T, Mikkilineni, Shravani, MacDermott, Amy B, Woolf, Clifford J, Henderson, Christopher E

“…Previous work has suggested that induced pluripotent stem cells (iPSCs) are inferior to embryonic stem cells (ESCs) with respect to in vitro differentiation,…”
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Maturation of spinal motor neurons derived from human embryonic stem cells by Takazawa, Tomonori, Croft, Gist F, Amoroso, Mackenzie W, Studer, Lorenz, Wichterle, Hynek, Macdermott, Amy B

“…Our understanding of motor neuron biology in humans is derived mainly from investigation of human postmortem tissue and more indirectly from live animal models…”
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The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis by Ikiz, Burcin, Alvarez, Mariano J., Ré, Diane B., Le Verche, Virginia, Politi, Kristin, Lotti, Francesco, Phani, Sudarshan, Pradhan, Radhika, Yu, Changhao, Croft, Gist F., Jacquier, Arnaud, Henderson, Christopher E., Califano, Andrea, Przedborski, Serge

“…Neurodegenerative phenotypes reflect complex, time-dependent molecular processes whose elucidation may reveal neuronal class-specific therapeutic targets. The…”
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Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth by Li, Hai, Kuwajima, Takaaki, Oakley, Derek, Nikulina, Elena, Hou, Jianwei, Yang, Wan Seok, Lowry, Emily Rhodes, Lamas, Nuno Jorge, Amoroso, Mackenzie Weygandt, Croft, Gist F., Hosur, Raghavendra, Wichterle, Hynek, Sebti, Said, Filbin, Marie T., Stockwell, Brent, Henderson, Christopher E.

“…Suboptimal axonal regeneration contributes to the consequences of nervous system trauma and neurodegenerative disease, but the intrinsic mechanisms that…”
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Discovery of novel isoforms of huntingtin reveals a new hominid-specific exon by Ruzo, Albert, Ismailoglu, Ismail, Popowski, Melissa, Haremaki, Tomomi, Croft, Gist F, Deglincerti, Alessia, Brivanlou, Ali H

“…Huntington's disease (HD) is a devastating neurological disorder that is caused by an expansion of the poly-Q tract in exon 1 of the Huntingtin gene (HTT). HTT…”
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Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway by Palmer, Colin J, Galan-Caridad, Jose M, Weisberg, Stuart P, Lei, Liang, Esquilin, Jose M, Croft, Gist F, Wainwright, Brandon, Canoll, Peter, Owens, David M, Reizis, Boris

“…The Hedgehog (Hh) signaling pathway regulates normal development and cell proliferation in metazoan organisms, but its aberrant activation can promote…”
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Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development by Rommel, Philipp C, Bosque, David, Gitlin, Alexander D, Croft, Gist F, Heintz, Nathaniel, Casellas, Rafael, Nussenzweig, Michel C, Kriaucionis, Skirmantas, Robbiani, Davide F

“…The Aicda gene encodes Activation-Induced cytidine Deaminase (AID), an enzyme essential for remodeling antibody genes in mature B lymphocytes. AID is also…”
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Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons by Dimos, John T., Rodolfa, Kit T., Niakan, Kathy K., Weisenthal, Laurin M., Mitsumoto, Hiroshi, Chung, Wendy, Croft, Gist F., Saphier, Genevieve, Leibel, Rudy, Goland, Robin, Wichterle, Hynek, Henderson, Christopher E., Eggan, Kevin

“…The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's…”
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Chromosomal instability during neurogenesis in Huntington's disease by Ruzo, Albert, Croft, Gist F, Metzger, Jakob J, Galgoczi, Szilvia, Gerber, Lauren J, Pellegrini, Cecilia, Wang, Jr, Hanbin, Fenner, Maria, Tse, Stephanie, Marks, Adam, Nchako, Corbyn, Brivanlou, Ali H

“…Huntington's disease (HD) is a fatal neurodegenerative disease caused by expansion of CAG repeats in the Huntingtin gene ( ). Neither its pathogenic mechanisms…”
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Discovery of Novel Isoforms of Huntingtin Reveals a New Hominid-Specific Exon: e0127687 by Ruzo, Albert, Ismailoglu, Ismail, Popowski, Melissa, Haremaki, Tomomi, Croft, Gist F, Deglincerti, Alessia, Brivanlou, Ali H

“…Huntington's disease (HD) is a devastating neurological disorder that is caused by an expansion of the poly-Q tract in exon 1 of the Huntingtin gene (HTT). HTT…”
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A functionally characterized test set of human induced pluripotent stem cells by Boulting, Gabriella L, Kiskinis, Evangelos, Croft, Gist F, Amoroso, Mackenzie W, Oakley, Derek H, Wainger, Brian J, Williams, Damian J, Kahler, David J, Yamaki, Mariko, Davidow, Lance, Rodolfa, Christopher T, Dimos, John T, Mikkilineni, Shravani, MacDermott, Amy B, Woolf, Clifford J, Henderson, Christopher E, Wichterle, Hynek, Eggan, Kevin

“…Human induced pluripotent stem cells (iPSCs) present exciting opportunities for studying development and for in vitro disease modeling. However, reported…”
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Defining and Controlling the Subtype Identity of Human Stem Cell-Derived Motor Neurons by Croft, Gist F

“…One cardinal promise of stem cell research is that many intractable, common, and poorly understood diseases may be studied in an entirely new way: in vitro in…”
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Fate Mapping for Activation-Induced Cytidine Deaminase (AID) Marks Non-Lymphoid Cells During Mouse Development. e69208 by Rommel, Philipp C, Bosque, David, Gitlin, Alexander D, Croft, Gist F, Heintz, Nathaniel, Casellas, Rafael, Nussenzweig, Michel C, Kriaucionis, Skirmantas, Robbiani, Davide F

“…The Aicda gene encodes Activation-Induced cytidine Deaminase (AID), an enzyme essential for remodeling antibody genes in mature B lymphocytes. AID is also…”
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Defining and Controlling the Subtype Identity of Human Stem Cell-Derived Motor Neurons by Croft, Gist F

“…One cardinal promise of stem cell research is that many intractable, common, and poorly understood diseases may be studied in an entirely new way: in vitro in…”
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Sex Hormones and Cytokines in Central Nervous System Pathology and Repair by GottfriedBlackmore, Andrés, Croft, Gist F., Bulloch, Karen

“…The adult central nervous system (CNS) is far more capable of repair and regeneration than previously believed. Research in the field of neuroendocrine…”
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