Search Results - "Croft, Amanda"

Sex-based differences in short- and longer-term diet-induced metabolic heart disease by Croft, Amanda J, Kelly, Conagh, Chen, Dongqing, Haw, Tatt Jhong, Balachandran, Lohis, Murtha, Lucy A, Boyle, Andrew J, Sverdlov, Aaron L, Ngo, Doan T M

“…Sex-based differences in the development of obesity-induced cardiometabolic dysfunction are well documented, however, the specific mechanisms are not…”
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P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation by Avery-Kiejda, Kelly A, Bowden, Nikola A, Croft, Amanda J, Scurr, Lyndee L, Kairupan, Carla F, Ashton, Katie A, Talseth-Palmer, Bente A, Rizos, Helen, Zhang, Xu D, Scott, Rodney J, Hersey, Peter

“…Metastatic melanoma represents a major clinical problem. Its incidence continues to rise in western countries and there are currently no curative treatments…”
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Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells by Wang, Yu Fang, Liu, Fen, Sherwin, Simonne, Farrelly, Margaret, Yan, Xu Guang, Croft, Amanda, Liu, Tao, Jin, Lei, Zhang, Xu Dong, Jiang, Chen Chen

“…Although the expression of programmed death-ligand 1 (PD-L1) is an important mechanism by which cancer cells evade the immune system, PD-L1 expression in…”
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Landscape fire smoke airway exposure impairs respiratory and cardiac function and worsens experimental asthma by Gomez, Henry M., Haw, Tatt J., Ilic, Dusan, Robinson, Peter, Donovan, Chantal, Croft, Amanda J., Vanka, Kanth S., Small, Ellen, Carroll, Olivia R., Kim, Richard Y., Mayall, Jemma R., Beyene, Tesfalidet, Palanisami, Thava, Ngo, Doan T.M., Zosky, Graeme R., Holliday, Elizabeth G., Jensen, Megan E., McDonald, Vanessa M., Murphy, Vanessa E., Gibson, Peter G., Horvat, Jay C.

“…[Display omitted] Millions of people are exposed to landscape fire smoke (LFS) globally, and inhalation of LFS particulate matter (PM) is associated with poor…”
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RIP1 Kinase Is an Oncogenic Driver in Melanoma by Liu, Xiao Ying, Lai, Fritz, Yan, Xu Guang, Jiang, Chen Chen, Guo, Su Tang, Wang, Chun Yan, Croft, Amanda, Tseng, Hsin-Yi, Wilmott, James S, Scolyer, Richard A, Jin, Lei, Zhang, Xu Dong

“…Although many studies have uncovered an important role for the receptor-binding protein kinase RIP1 in controlling cell death signaling, its possible…”
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Cancer Therapies and Cardiomyocyte Viability: Which Drugs are Directly Cardiotoxic? by Balachandran, Lohis, Haw, Tatt Jhong, Leong, Angeline Jia Wen, Croft, Amanda J., Chen, Dongqing, Kelly, Conagh, Sverdlov, Aaron L., Ngo, Doan T.M.

“…Increased cancer survivorship represents a remarkable achievement for modern medicine. Unfortunately, cancer treatments have inadvertently contributed to…”
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Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress by Croft, Amanda, Tay, Kwang H., Boyd, Suzanah C., Guo, Su T., Jiang, Chen C., Lai, Fritz, Tseng, Hsin-Yi, Jin, Lei, Rizos, Helen, Hersey, Peter, Zhang, Xu D.

“…Cancer cells commonly undergo chronic endoplasmic reticulum (ER) stress, to which the cells have to adapt for survival and proliferation. We report here that…”
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Medical graduates becoming rural doctors: rural background versus extended rural placement by Clark, Tyler R, Freedman, Saul B, Croft, Amanda J, Dalton, Hazel E, Luscombe, Georgina M, Brown, Anthony M, Tiller, David J, Frommer, Michael S

“…Objectives: To determine whether recruitment of rural students and uptake of extended rural placements are associated with students’ expressed intentions to…”
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Reactive Oxygen Species Dictate the Apoptotic Response of Melanoma Cells to TH588 by Wang, Jia Yu, Jin, Lei, Yan, Xu Guang, Sherwin, Simonne, Farrelly, Margaret, Zhang, Yuan Yuan, Liu, Fen, Wang, Chun Yan, Guo, Su Tang, Yari, Hamed, La, Ting, McFarlane, Jennifer, Lei, Fu Xi, Tabatabaee, Hessam, Chen, Jie Zhong, Croft, Amanda, Jiang, Chen Chen, Zhang, Xu Dong

“…The effect of MTH1 inhibition on cancer cell survival has been elusive. Here we report that although silencing of MTH1 does not affect survival of melanoma…”
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Overexpression of Mitochondrial Catalase within Adipose Tissue Does Not Confer Systemic Metabolic Protection against Diet-Induced Obesity by Croft, Amanda J, Kelly, Conagh, Chen, Dongqing, Haw, Tatt Jhong, Sverdlov, Aaron L, Ngo, Doan T M

“…Obesity is associated with significant metabolic co-morbidities, such as diabetes, hypertension, and dyslipidaemia, as well as a range of cardiovascular…”
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OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis by Wroblewski, David, Jiang, Chen Chen, Croft, Amanda, Farrelly, Margaret L, Zhang, Xu Dong, Hersey, Peter

“…Anti-apoptotic Bcl-2 family proteins, in particular, Mcl-1, are known to play a critical role in resistance of human melanoma cells to induction of apoptosis…”
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Association of Circulating Plasma Secreted Frizzled-Related Protein 5 (Sfrp5) Levels with Cardiac Function by Kelly, Conagh J, Chu, Matthew, Untaru, Rossana, Assadi-Khansari, Bahador, Chen, Dongqing, Croft, Amanda J, Horowitz, John D, Boyle, Andrew J, Sverdlov, Aaron L, Ngo, Doan T M

“…Secreted frizzled-related protein 5 (SFRP5) is a novel anti-inflammatory adipokine that may play a role in cardiovascular development and disease. However,…”
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Heart Failure in Breast Cancer Survivors: Focus on Early Detection and Novel Biomarkers by Chen, Dongqing, Kelly, Conagh, Haw, Tatt Jhong, Lombard, Janine M., Nordman, Ina I. C., Croft, Amanda J., Ngo, Doan T. M., Sverdlov, Aaron L.

“…Purpose of Review Breast cancer survival rate has greatly improved in the last two decades due to the emergence of next-generation anti-cancer agents. However,…”
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INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas by Chi, Meng Na, Guo, Su Tang, Wilmott, James S, Guo, Xiang Yun, Yan, Xu Guang, Wang, Chun Yan, Liu, Xiao Ying, Jin, Lei, Tseng, Hsin-Yi, Liu, Tao, Croft, Amanda, Hondermarck, Hubert, Scolyer, Richard A, Jiang, Chen Chen, Zhang, Xu Dong

“…Inositol polyphosphate 4-phosphatase type II (INPP4B) negatively regulates PI3K/Akt signalling and has a tumour suppressive role in some types of cancers…”
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Elevated Soluble Suppressor of Tumorigenicity 2 Predict Hospital Admissions Due to Major Adverse Cardiovascular Events (MACE) by Chen, Dongqing, Untaru, Rossana, Stavropoulou, Glykeria, Assadi-Khansari, Bahador, Kelly, Conagh, Croft, Amanda J, Sugito, Stuart, Collins, Nicholas J, Sverdlov, Aaron L, Ngo, Doan T M

“…The role of soluble suppression of tumorigenicity (sST2) as a biomarker in predicting clinical outcomes in patients with cardiovascular diseases (CVD) has not…”
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2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2 by Liu, Hao, Jiang, Chen Chen, Lavis, Christopher J, Croft, Amanda, Dong, Li, Tseng, Hsin-Yi, Yang, Fan, Tay, Kwang Hong, Hersey, Peter, Zhang, Xu Dong

“…Past studies have shown that sensitivity of melanoma cells to TRAIL-induced apoptosis is largely correlated with the expression levels of TRAIL death receptors…”
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Nuclear matrix binding is critical for progesterone receptor movement into nuclear foci by Graham, J. Dinny, Hanson, Adrienne R., Croft, Amanda J., Fox, Archa H., Clarke, Christine L.

“…The ovarian hormone progesterone is essential for normal breast development, and progesterone analogues are implicated in increasing breast cancer risk. The…”
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Gene expression profiling in familial adenomatous polyposis adenomas and desmoid disease by Bowden, Nikola A, Croft, Amanda, Scott, Rodney J

“…Gene expression profiling is a powerful method by which alterations in gene expression can be interrogated in a single experiment. The disease familial…”
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Seeing through crocodile tears? Sex-specific associations between the Dark Triad traits and lie detection accuracy by Lyons, Minna, Croft, Amanda, Fairhurst, Sian, Varley, Katie, Wilson, Clarissa

“…Although overall people are poor at lie detection, the accuracy depends on the situation (e.g., high versus low-stakes), as well as the characteristics of the…”
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Breaking bad news: How doctors communicate life-threatening diagnoses on television by Elzinga, Katrina, Croft, Amanda, Steffan, Richard, Bivins, Kyle, Ramon, Kaleb, Frick, Kurt, Fellows, Austin, Devireddy, Deepthi, Johnson, Ainslie, Jones, Jeffrey

“…To ensure quality control of collected data, a faculty member reviewed the data sheets to reduce any interobserver variations or errors in data transcription…”
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