Search Results - "Croci, Nicole"
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Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: a twelve-week follow-up study
Published in Journal of neurotrauma (01-05-2010)“…Traumatic brain injury (TBI) causes a wide spectrum of consequences, such as microglial activation, cerebral inflammation, and focal and diffuse brain injury,…”
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Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury
Published in BMC molecular biology (08-07-2008)“…Traumatic brain injury models are widely studied, especially through gene expression, either to further understand implied biological mechanisms or to assess…”
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Deleterious poly(ADP-ribose)polymerase-1 pathway activation in traumatic brain injury in rat
Published in Brain research (31-10-2003)“…Traumatic brain injury produces nitric oxide and reactive oxygen species. Peroxynitrite, resulting from the combination of nitric oxide and superoxide anions,…”
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l-NAME reduces infarction, neurological deficit and blood–brain barrier disruption following cerebral ischemia in mice
Published in European journal of pharmacology (20-12-2002)“…The role of nitric oxide (NO) in the development of post-ischemic cerebral infarction has been extensively examined, but fewer studies have investigated its…”
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3-Aminobenzamide reduces brain infarction and neutrophil infiltration after transient focal cerebral ischemia in mice
Published in Experimental neurology (01-12-2003)“…Poly(ADP-ribose) polymerase (PARP) was shown to be detrimental in cerebral ischemia but the mechanisms whereby PARP is deleterious have yet to be determined…”
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Investigating drug-gut microbiota interactions: reductive and hydrolytic metabolism of oral glucocorticoids by in vitro artificial gut microbiota
Published in International journal of pharmaceutics (15-11-2024)“…[Display omitted] •Understanding the role of gut microbiota in drug metabolism can improve therapeutic effectiveness.•Artificial gut microbiota (AGM) can be…”
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Neuroprotective effects of (S)-N-[4-[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)carbonyl]-1-piperazinyl]phenyl]-2-thiophenecarboximid-amide (BN 80933), an inhibitor of neuronal nitric-oxide synthase and an antioxidant, in model of transient focal cerebral ischemia in mice
Published in The Journal of pharmacology and experimental therapeutics (01-08-2003)“…Nitric oxide (NO) and reactive oxygen species are both implicated in neuronal death due to cerebral ischemia. BN 80933, an original compound associating an…”
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Minocycline effects on cerebral edema: Relations with inflammatory and oxidative stress markers following traumatic brain injury in mice
Published in Brain research (21-09-2009)“…Abstract One of the severe complications following traumatic brain injury (TBI) is cerebral edema and its effective treatment is of great interest to prevent…”
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Minocycline restores sAPPα levels and reduces the late histopathological consequences of traumatic brain injury in mice
Published in Journal of neurotrauma (01-10-2011)“…Traumatic brain injury (TBI) induces both focal and diffuse lesions that are concurrently responsible for the ensuing morbidity and mortality and for which no…”
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Effects of selective and non-selective cyclooxygenase inhibition against neurological deficit and brain oedema following closed head injury in mice
Published in Brain research (23-01-2013)“…Abstract The implication of cyclooxygenase (COX) type 2 in post-traumatic consequences is so far controversial. In experimental models of traumatic brain…”
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NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production
Published in The Journal of neuroscience (12-10-2005)“…Acute brain injuries have been identified as a risk factor for developing Alzheimer's disease (AD). Because glutamate plays a pivotal role in these…”
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Characterization of a rat model to study acute neuroinflammation on histopathological, biochemical and functional outcomes
Published in Journal of neuroscience methods (15-06-2005)“…Neuroinflammation is one of the events occurring after acute brain injuries. The aim of the present report was to characterize a rat model to study acute…”
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Polymorphonuclear neutrophils contribute to infarction and oxidative stress in the cortex but not in the striatum after ischemia–reperfusion in rats
Published in Brain research (10-10-2003)“…The present work examined whether polymorphonuclear neutrophil (PMN) infiltration contributes to cortical and striatal brain damage and oxidative stress in a…”
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Biphasic modulation by nitric oxide of caspase activation due to malonate injection in rat striatum
Published in European journal of pharmacology (12-01-2004)“…The present study examined caspase activation and its modulation by nitric oxide (NO) in a model of oxidative stress induced by injection of malonate (3 μmol),…”
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NMDA Receptor Activation Inhibits {alpha}-Secretase and Promotes Neuronal Amyloid-{beta} Production
Published in The Journal of neuroscience (12-10-2005)Get full text
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Inhibition by aminoacetonitrile and propargylamine of glycine cleavage system from rat brain and liver mitochondria
Published in Biochemical pharmacology (01-01-1983)“…Glycine degradation in the CNS is catalyzed by the glycine cleavage system (GCS). We have tested several compounds with a structural analogy to glycine for…”
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