Search Results - "Croce, M."
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Causes and consequences of microRNA dysregulation in cancer
Published in Nature reviews. Genetics (01-10-2009)“…Key Points This paper describes the alterations and mechanisms that are involved in microRNA (miRNA) dysregulation in human cancer and how such dysregulation…”
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MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies
Published in Experimental & molecular medicine (01-07-2023)“…As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in cancer development. Since the discovery of the identity and clinical…”
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3
MicroRNAs in cancer
Published in Annual review of pathology (01-01-2014)“…MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and stability of messenger RNAs (mRNAs), controlling genes involved in…”
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The role of MicroRNAs in human cancer
Published in Signal transduction and targeted therapy (01-01-2016)“…MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of gene expression. Compelling evidences have demonstrated that miRNA…”
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Targeting microRNAs in cancer: rationale, strategies and challenges
Published in Nature reviews. Drug discovery (01-10-2010)“…Key Points The rationale for using microRNAs (miRNAs) as anticancer drugs is based on two major findings: miRNA expression is deregulated in cancer compared…”
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MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
Published in EMBO molecular medicine (01-03-2012)“…Early studies have shown how aberrantly expressed microRNAs are a hallmark of several diseases like cancer. MicroRNA expression profiling was shown to be…”
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MicroRNAs in Cancer: Small Molecules With a Huge Impact
Published in Journal of clinical oncology (01-12-2009)“…Every cellular process is likely to be regulated by microRNAs, and an aberrant microRNA expression signature is a hallmark of several diseases, including…”
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Finally, An Apoptosis-Targeting Therapeutic for Cancer
Published in Cancer research (Chicago, Ill.) (15-10-2016)“…Resistance to cell death represents one of the hallmarks of cancer. Various genetic and epigenetic changes in malignant cells afford cytoprotection in the face…”
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microRNA involvement in human cancer
Published in Carcinogenesis (New York) (01-06-2012)“…When, ∼20 years ago, investigators first determined that components of the genome considered nonfunctional had, in fact, gene regulatory capacity, they…”
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Role of microRNAs in maintaining cancer stem cells
Published in Advanced drug delivery reviews (01-01-2015)“…Increasing evidence sustains that the establishment and maintenance of many, if not all, human cancers are due to cancer stem cells (CSCs), tumor cells with…”
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microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
Published in Oncogene (24-11-2011)“…The human genome is replete with long non-coding RNAs (lncRNA), many of which are transcribed and likely to have a functional role. Microarray analysis of >23…”
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MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
Published in EMBO molecular medicine (01-06-2017)Get full text
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microRNAs: Master regulators as potential therapeutics in cancer
Published in Annual review of pharmacology and toxicology (10-02-2011)“…It has been demonstrated that all the known processes involved in cancer, including apoptosis, proliferation, survival, and metastasis, are regulated by small…”
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Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer
Published in Proceedings of the National Academy of Sciences - PNAS (30-04-2013)“…The optimal management of breast cancer (BC) presents challenges due to the heterogeneous molecular classification of the disease. We performed survival…”
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Long noncoding RNAs: Undeciphered cellular codes encrypting keys of colorectal cancer pathogenesis
Published in Cancer letters (28-03-2018)“…Long noncoding RNAs are non-protein coding transcripts longer than 200 nucleotides in length. By the advance in genetic and bioinformatic technologies, the new…”
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Risks for the Long Run and the Real Exchange Rate
Published in The Journal of political economy (01-02-2011)“…We propose an equilibrium model that can explain a wide range of international finance puzzles, including the high correlation of international stock markets,…”
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miR221/222 in cancer: their role in tumor progression and response to therapy
Published in Current molecular medicine (01-01-2012)“…miRNAs are small non-coding RNAs of ~24 nt that can block mRNA translation and/or negatively regulate its stability. There is a large body of evidence that…”
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MicroRNAs in Cancer
Published in Annual review of medicine (01-01-2009)“…MicroRNAs (miRNAs) are small, noncoding RNAs with important functions in development, cell differentiation, and regulation of cell cycle and apoptosis. MiRNA…”
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Government debt and the returns to innovation
Published in Journal of financial economics (01-06-2019)“…Elevated levels of government debt raise concerns about their effects on long-term growth prospects. Using the cross-section of US stock returns, we show that…”
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Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression
Published in Nature nanotechnology (01-01-2018)“…Nanotechnology offers many benefits, and here we report an advantage of applying RNA nanotechnology for directional control. The orientation of arrow-shaped…”
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