Search Results - "Critchley, Ian"

The burden of antimicrobial resistance among urinary tract isolates of Escherichia coli in the United States in 2017 by Critchley, Ian A, Cotroneo, Nicole, Pucci, Michael J, Mendes, Rodrigo

“…Urinary tract infections (UTIs) caused by Escherichia coli have been historically managed with oral antibiotics including the cephalosporins, fluoroquinolones…”
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Avibactam Pharmacokinetic/Pharmacodynamic Targets by Nichols, Wright W, Newell, Paul, Critchley, Ian A, Riccobene, Todd, Das, Shampa

“…Avibactam is a novel non-β-lactam β-lactamase inhibitor that has been approved in the United States and Europe for use in combination with ceftazidime…”
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Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection by Cotroneo, Nicole, Stokes, Suzanne S, Pucci, Michael J, Rubio, Aileen, Hamed, Kamal A, Critchley, Ian A

“…Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide, with Mycobacterium avium complex (MAC) and Mycobacterium abscessus as the…”
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Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection by Eckburg, Paul B, Muir, Lori, Critchley, Ian A, Walpole, Susannah, Kwak, Hanna, Phelan, Anne-Marie, Moore, Gary, Jain, Akash, Keutzer, Tim, Dane, Aaron, Melnick, David, Talley, Angela K

“…Oral antibacterial agents that are active against antimicrobial-resistant bacteria are needed. In this double-dummy, randomized, controlled trial, tebipenem…”
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Dose Selection and Validation for Ceftazidime-Avibactam in Adults with Complicated Intra-abdominal Infections, Complicated Urinary Tract Infections, and Nosocomial Pneumonia by Das, Shampa, Li, Jianguo, Riccobene, Todd, Carrothers, Timothy J, Newell, Paul, Melnick, David, Critchley, Ian A, Stone, Gregory G, Nichols, Wright W

“…Avibactam is a non-β-lactam β-lactamase inhibitor that has been approved in combination with ceftazidime for the treatment of complicated intra-abdominal…”
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In Vitro and In Vivo Characterization of Tebipenem, an Oral Carbapenem by Cotroneo, Nicole, Rubio, Aileen, Critchley, Ian A, Pillar, Chris, Pucci, Michael J

“…The continued evolution of bacterial resistance to the β-lactam class of antibiotics has necessitated countermeasures to ensure continued effectiveness in the…”
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Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections by McEntee, Laura, Johnson, Adam, Farrington, Nicola, Unsworth, Jennifer, Dane, Aaron, Jain, Akash, Cotroneo, Nicole, Critchley, Ian, Melnick, David, Parr, Thomas, Ambrose, Paul G, Das, Shampa, Hope, William

“…Tebipenem pivoxil HBr (TBPM-PI-HBr) is a novel orally bioavailable carbapenem. The active moiety is tebipenem. Tebipenem pivoxil is licensed for use in Japan…”
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Impact of antibiotic pharmacokinetics in urine on recurrent bacteriuria following treatment of complicated urinary tract infections by Melnick, David, Talley, Angela K., Gupta, Vipul K., Critchley, Ian A., Eckburg, Paul B., Hamed, Kamal A., Bhatt, Nivedita, Moore, Gary, Austin, Daren, Rubino, Christopher M., Bhavnani, Sujata M., Ambrose, Paul G.

“…ABSTRACT The clinical relevance of bacteriuria following antibiotic treatment of complicated urinary tract infections in clinical trials remains controversial…”
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Ceftazidime-Avibactam Susceptibility Breakpoints against Enterobacteriaceae and Pseudomonas aeruginosa by Nichols, Wright W, Stone, Gregory G, Newell, Paul, Broadhurst, Helen, Wardman, Angela, MacPherson, Merran, Yates, Katrina, Riccobene, Todd, Critchley, Ian A, Das, Shampa

“…Clinical susceptibility breakpoints against and for the ceftazidime-avibactam dosage regimen of 2,000/500 mg every 8 h (q8h) by 2-h intravenous infusion…”
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Resistance among urinary tract pathogens collected in Europe during 2018 by Critchley, Ian A, Cotroneo, Nicole, Pucci, Michael J., Jain, Akash, Mendes, Rodrigo E.

“…•Among uropathogens, antibiotic resistance was high, especially for ESBL phenotypes.•Meropenem was the most active drug against E. coli, K. pneumoniae and P…”
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Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity by Biek, Donald, Critchley, Ian A., Riccobene, Todd A., Thye, Dirk A.

“…Ceftaroline fosamil is a novel cephalosporin with broad-spectrum activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus…”
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Serotype distribution and antimicrobial susceptibility of USA Streptococcus pneumoniae isolates collected prior to and post introduction of 13-valent pneumococcal conjugate vaccine by Mendes, Rodrigo E, Costello, Andrew J, Jacobs, Michael R, Biek, Donald, Critchley, Ian A, Jones, Ronald N

“…Abstract This study evaluated pneumococci cultured from blood or lower respiratory tract specimens from hospitalized patients in the USA (all age groups)…”
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Activity of Ceftaroline and Epidemiologic Trends in Staphylococcus aureus Isolates Collected from 43 Medical Centers in the United States in 2009 by RICHTER, Sandra S, HEILMANN, Kristopher P, DOHRN, Cassie L, RIAHI, Fathollah, COSTELLO, Andrew J, KROEGER, Jennifer S, BIEK, Donald, CRITCHLEY, Ian A, DIEKEMA, Daniel J, DOERN, Gary V

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In Vitro Resistance against DNA Gyrase Inhibitor SPR719 in Mycobacterium avium and Mycobacterium abscessus by Aragaw, Wassihun Wedajo, Cotroneo, Nicole, Stokes, Suzanne, Pucci, Michael, Critchley, Ian, Gengenbacher, Martin, Dick, Thomas

“…The aminobenzimidazole SPR719 targets DNA gyrase in Mycobacterium tuberculosis. The molecule acts as inhibitor of the enzyme's ATPase located on the Gyrase B…”
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Activity of Ceftaroline against Recent Emerging Serotypes of Streptococcus pneumoniae in the United States by JACOBS, Michael R, GOOD, Caryn E, WINDAU, Anne R, BAJAKSOUZIAN, Saralee, BIEK, Donald, CRITCHLEY, Ian A, SADER, Helio S, JONES, Ronald N

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Assessment of 30/20-Microgram Disk Content versus MIC Results for Ceftazidime-Avibactam Tested against Enterobacteriaceae and Pseudomonas aeruginosa by Sader, Helio S, Rhomberg, Paul R, Huband, Michael D, Critchley, Ian A, Stone, Gregory G, Flamm, Robert K, Jones, Ronald N

“…We evaluated the correlation between MIC and disk diffusion inhibition zones when testing ceftazidime-avibactam, using the 30/20-μg disk and the disk diffusion…”
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Pharmacodynamics of β-Lactamase Inhibition by NXL104 in Combination with Ceftaroline: Examining Organisms with Multiple Types of β-Lactamases by LOUIE, Arnold, CASTANHEIRA, Mariana, KULAWY, Robert, DRUSANO, G. L, WEIGUO LIU, GRASSO, Caroline, JONES, Ronald N, WILLIAM, Gregory, CRITCHLEY, Ian, THYE, Dirk, BROWN, David, VANSCOY, Brian

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Randomized Trial of Ceftazidime-Avibactam vs Meropenem for Treatment of Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia (REPROVE): Analyses per US FDA-Specified End Points by Torres, Antoni, Rank, Doug, Melnick, David, Rekeda, Ludmyla, Chen, Xiang, Riccobene, Todd, Critchley, Ian A, Lakkis, Hassan D, Taylor, Dianna, Talley, Angela K

“…Hospital-acquired and ventilator-associated pneumonia (HAP/VAP; nosocomial pneumonia) due to Gram-negative pathogens are associated with significant morbidity…”
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Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Evaluate In Vitro Susceptibility Test Interpretive Criteria for Ceftaroline against Staphylococcus aureus and Streptococcus pneumoniae by VAN WART, Scott A, AMBROSE, Paul G, RUBINO, Christopher M, KHARITON, Tatiana, RICCOBENE, Todd A, FRIEDLAND, H. David, CRITCHLEY, Ian A, BHAVNANI, Sujata M

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Decreased Ceftriaxone Susceptibility in Emerging (35B and 6C) and Persisting (19A) Streptococcus pneumoniae Serotypes in the United States, 2011-2012: Ceftaroline Remains Active In Vitro among β-Lactam Agents by MENDES, Rodrigo E, BIEK, Donald, CRITCHLEY, Ian A, FARRELL, David J, SADER, Helio S, JONES, Ronald N

“…Totals of 8.7% (103/1,190) and 21.0% (249/1,190) of the Streptococcus pneumoniae isolates recovered from specimens collected in the United States during the…”
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