Search Results - "Cristy, Shane"

Antimicrobial Peptides: a New Frontier in Antifungal Therapy by Buda De Cesare, Giuseppe, Cristy, Shane A, Garsin, Danielle A, Lorenz, Michael C

“…Invasive fungal infections in humans are generally associated with high mortality, making the choice of antifungal drug crucial for the outcome of the patient…”
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During bacteremia, Pseudomonas aeruginosa PAO1 adapts by altering the expression of numerous virulence genes including those involved in quorum sensing by Beasley, Kellsie L, Cristy, Shane A, Elmassry, Moamen M, Dzvova, Nyaradzo, Colmer-Hamood, Jane A, Hamood, Abdul N

“…Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that produces numerous virulence factors and causes serious infections in trauma patients and…”
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Optimization of the antifungal properties of the bacterial peptide EntV by variant analysis by Guha, Shantanu, Cristy, Shane A, Buda De Cesare, Giuseppe, Cruz, Melissa R, Lorenz, Michael C, Garsin, Danielle A

“…Fungal resistance to commonly used medicines is a growing public health threat, and there is a dire need to develop new classes of antifungals. We previously…”
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Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections by Cruz, Melissa R., Cristy, Shane, Guha, Shantanu, De Cesare, Giuseppe Buda, Evdokimova, Elena, Sanchez, Hiram, Borek, Dominika, Miramón, Pedro, Yano, Junko, Fidel, Paul L., Savchenko, Alexei, Andes, David R., Stogios, Peter J., Lorenz, Michael C., Garsin, Danielle A.

“…Fungal pathogens are a continuing challenge due to few effective antifungals and a rise in resistance. In previous work, we described the inhibition of Candida…”
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Short peptides derived from EntV inhibit virulence and biofilm formation in Candida albicans by Cristy, Shane, Garsin, Danielle, Lorenz, Michael

“…Candida albicans exists as a member of the commensal flora of the skin and gut where many complex polymicrobial interactions occur with genera such as…”
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