Search Results - "Cristine Dieter"
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Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis
Published in PloS one (06-07-2022)“…Although advanced age and presence of comorbidities significantly impact the variation observed in the clinical symptoms of COVID-19, it has been suggested…”
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Association of long non-coding RNA and leukemia: A systematic review
Published in Gene (20-04-2020)“…Long non-coding RNAs (lncRNAs) are RNA molecules that structurally resemble mRNA but do not encode proteins. Studies have been associated this class of…”
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The Impact of lncRNAs in Diabetes Mellitus: A Systematic Review and In Silico Analyses
Published in Frontiers in endocrinology (Lausanne) (19-03-2021)“…Long non-coding RNAs (lncRNAs) are non-coding transcripts that have emerged as one of the largest and diverse RNA families that regulate gene expression…”
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Association between the G/G genotype of the lncRNA MEG3 rs7158663 polymorphism and proliferative diabetic retinopathy
Published in Archives of Endocrinology and Metabolism (21-10-2024)“…ABSTRACT Objective: To investigate the association between the long noncoding RNAs (lncRNAs) maternally expressed gene 3 (MEG3) rs7158663 polymorphism and…”
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Association of TYK2 polymorphisms with autoimmune diseases: A comprehensive and updated systematic review with meta-analysis
Published in Genetics and molecular biology (01-01-2021)“…Autoimmune diseases are characterized by the loss of self-tolerance, leading to immune-mediated tissue destruction and chronic inflammation. Tyrosine kinase 2…”
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The rs1800469 T/T and rs1800470 C/C genotypes of the TGFB1 gene confer protection against diabetic retinopathy in a Southern Brazilian population
Published in Genetics and molecular biology (01-01-2023)“…The transforming growth factor beta 1 (TGFB1) is a pro-inflammatory cytokine that plays a key role in the mechanisms of angiogenesis and breakdown of the…”
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MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney Disease
Published in Frontiers in genetics (12-06-2019)“…Diabetic kidney disease (DKD) is a common microvascular complication that affects 40% of patients with diabetes mellitus (DM). Emerging evidence suggests a…”
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The A allele of the rs759853 single nucleotide polymorphism in the AKR1B1 gene confers risk for diabetic kidney disease in patients with type 2 diabetes from a Brazilian population
Published in Archives of Endocrinology and Metabolism (01-01-2022)“…The gene encodes an enzyme that catalyzes the reduction of glucose into sorbitol. Chronic hyperglycemia in patients with diabetes mellitus (DM) leads to…”
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Polymorphisms in TIE2 and ANGPT-1 genes are associated with protection against diabetic retinopathy in a Brazilian population
Published in Archives of Endocrinology and Metabolism (25-05-2023)“…The objective of this study was to investigate the association between SNPs in the and genes and diabetic retinopathy (DR). This study comprised 603 patients…”
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The rs2442598 polymorphism in the ANGPT-2 gene is associated with risk for diabetic retinopathy in patients with type 1 diabetes mellitus in a Brazilian population
Published in Archives of Endocrinology and Metabolism (24-11-2021)“…As studies have reported the involvement of angiopoietin-2 (ANGPT-2) in the pathogenesis of diabetic retinopathy (DR), the aim of this study was to investigate…”
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The rs2304256 Polymorphism in TYK2 Gene Is Associated with Protection for Type 1 Diabetes Mellitus
Published in Diabetes & metabolism journal (01-11-2021)“…Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory…”
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The rs11755527 polymorphism in the BACH2 gene and type 1 diabetes mellitus: case control study in a Brazilian population
Published in Archives of Endocrinology and Metabolism (01-04-2020)“…Objective Type 1 diabetes mellitus (T1DM) is an autoimmune disorder caused by a complex interaction between environmental and genetic risk factors. BTB domain…”
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866G/A and Ins/Del polymorphisms in the UCP2 gene and diabetic kidney disease: case-control study and meta-analysis
Published in Genetics and molecular biology (01-01-2020)“…Uncoupling protein 2 (UCP2) decreases reactive oxygen species (ROS). ROS overproduction is a key contributor to the pathogenesis of diabetic kidney disease…”
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Use of additives, scaffolds and extracellular matrix components for improvement of human pancreatic islet outcomes in vitro: A systematic review
Published in Islets (03-09-2017)“…Pancreatic islet transplantation is an established treatment to restore insulin independence in type 1 diabetic patients. Its success rates have increased…”
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The rs2304256 Polymorphism in TYK2 Gene Is Associated with Protection for Type 1 Diabetes Mellitus
Published in Diabetes & metabolism journal (30-11-2021)“…Background: Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and…”
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The rs705708 A allele of the ERBB3 gene is associated with lower prevalence of diabetic retinopathy and arterial hypertension and with improved renal function in type 1 diabetic patients
Published in Microvascular research (01-09-2022)“…The Erb-b2 receptor tyrosine kinase 3 (ERBB3) is involved in autoimmune processes related to type 1 diabetes mellitus (T1DM) pathogenesis. Accordingly, some…”
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Involvement of miR‐126 rs4636297 and miR‐146a rs2910164 polymorphisms in the susceptibility for diabetic retinopathy: a case–control study in a type 1 diabetes population
Published in Acta ophthalmologica (Oxford, England) (01-06-2021)“…Background and purpose MicroRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression. MiRNA‐126 and miRNA‐146a have been described as having…”
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The rs3931283/PVT1 and rs7158663/MEG3 polymorphisms are associated with diabetic kidney disease and markers of renal function in patients with type 2 diabetes mellitus
Published in Molecular biology reports (01-03-2023)“…Background Long non-coding RNAs (lncRNAs) are key regulators of gene expression. Some studies have reported the association of polymorphisms in lncRNA genes…”
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The lncRNA MALAT1 is upregulated in urine of type 1 diabetes mellitus patients with diabetic kidney disease
Published in Genetics and molecular biology (01-01-2023)“…Long non-coding RNAs (lncRNAs) are RNAs with >200 nucleotides that are unable to encode proteins and are involved in gene expression regulation. LncRNAs have a…”
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The rs2304256 Polymorphism in Gene Is Associated with Protection for Type 1 Diabetes Mellitus
Published in Diabetes & metabolism journal (01-11-2021)“…Background Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and…”
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