Search Results - "Cristian Scatena"

Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase by Fiorillo, Marco, Scatena, Cristian, Naccarato, Antonio Giuseppe, Sotgia, Federica, Lisanti, Michael P.

“…Here, we provide evidence that high ATP production by the mitochondrial ATP-synthase is a new therapeutic target for anticancer therapy, especially for…”
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Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC by Ferrari, Paola, Scatena, Cristian, Ghilli, Matteo, Bargagna, Irene, Lorenzini, Giulia, Nicolini, Andrea

“…Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high incidence of distant metastases, and poor overall survival (OS). Taxane and…”
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Cutaneous Melanoma Classification: The Importance of High-Throughput Genomic Technologies by Scatena, Cristian, Murtas, Daniela, Tomei, Sara

“…Cutaneous melanoma is an aggressive tumor responsible for 90% of mortality related to skin cancer. In the recent years, the discovery of driving mutations in…”
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Biomarkers for precision immunotherapy in the metastatic setting: hope or reality? by Sajjadi, Elham, Venetis, Konstantinos, Scatena, Cristian, Fusco, Nicola

“…Precision immunotherapy is a crucial approach to improve the efficacy of anti-cancer treatments, particularly in the metastatic setting. In this respect,…”
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Recent Advances in Cancer Plasticity: Cellular Mechanisms, Surveillance Strategies, and Therapeutic Optimization by Fanelli, Giuseppe Nicolò, Naccarato, Antonio Giuseppe, Scatena, Cristian

“…The processes of recurrence and metastasis, through which cancer relapses locally or spreads to distant sites in the body, accounts for more than 90% of…”
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New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes by Scatena, Cristian, Fanelli, Giovanni, Fanelli, Giuseppe Nicolò, Menicagli, Michele, Aretini, Paolo, Ortenzi, Valerio, Civitelli, Sara Piera, Innocenti, Lorenzo, Sotgia, Federica, Lisanti, Michael P., Naccarato, Antonio Giuseppe

“…Recent evidence suggests that a loss of expression of caveolin in the stromal compartment (sCav-1) of human invasive breast carcinoma (IBC) may be a predictor…”
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Androgen receptor expression inversely correlates with histological grade and N stage in ER+/PgRlow male breast cancer by Scatena, Cristian, Scarpitta, Rosa, Innocenti, Lorenzo, Miccoli, Mario, Biancotti, Rachele, Diodati, Lucrezia, Ghilli, Matteo, Naccarato, Antonio Giuseppe

“…Purpose Androgen Receptor (AR) positivity is often displayed in breast cancer and especially in Male Breast Cancer (MBC), where it appears to be a…”
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Editorial: Metabolic reprogramming in breast cancer by Scatena, Cristian, Naccarato, Antonio Giuseppe, Ozsvari, Bela, Scumaci, Domenica

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Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study by Scatena, Cristian, Roncella, Manuela, Di Paolo, Antonello, Aretini, Paolo, Menicagli, Michele, Fanelli, Giovanni, Marini, Carolina, Mazzanti, Chiara Maria, Ghilli, Matteo, Sotgia, Federica, Lisanti, Michael P, Naccarato, Antonio Giuseppe

“…Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers…”
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IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients by Crucitta, Stefania, Pasqualetti, Francesco, Gonnelli, Alessandra, Ruglioni, Martina, Luculli, Giovanna Irene, Cantarella, Martina, Ortenzi, Valerio, Scatena, Cristian, Paiar, Fabiola, Naccarato, Antonio Giuseppe, Danesi, Romano, Del Re, Marzia

“…Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and…”
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Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside by Morrone, Doralisa, Picoi, Maria Elena Lucia, Felice, Francesca, De Martino, Andrea, Scatena, Cristian, Spontoni, Paolo, Naccarato, Antonio Giuseppe, Di Stefano, Rossella, Bortolotti, Uberto, Dal Monte, Massimo, Pini, Stefano, Abelli, Marianna, Balbarini, Alberto

“…The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including…”
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Molecular characterization of low grade and high grade bladder cancer by Apollo, Alessandro, Ortenzi, Valerio, Scatena, Cristian, Zavaglia, Katia, Aretini, Paolo, Lessi, Francesca, Franceschi, Sara, Tomei, Sara, Sepich, Carlo Alberto, Viacava, Paolo, Mazzanti, Chiara Maria, Naccarato, Antonio Giuseppe

“…Bladder cancer (BC) is the 9th most common cancer diagnosis worldwide. Low grade (LG) represents 70% of all BCs, characterized by recurrence and rare ability…”
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Immunohistochemistry is highly sensitive and specific for the detection of NRASQ61R mutation in melanoma by Massi, Daniela, Simi, Lisa, Sensi, Elisa, Baroni, Gianna, Xue, Gongda, Scatena, Cristian, Caldarella, Adele, Pinzani, Pamela, Fontanini, Gabriella, Carobbio, Alessandra, Urso, Carmelo, Mandalà, Mario

“…Testing for NRAS is now integral part in the assessment of metastatic melanoma patients because there is evidence that NRAS -mutated patients may be sensitive…”
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A Budget Impact Analysis of the VENTANA PD-L1 SP142 Immunohistochemistry Assay Versus the Dako PD-L1 IHC 22C3 Assay in Patients With Advanced or Metastatic Triple-Negative Breast Cancer Treated With Atezolizumab in Combination With Nab-Paclitaxel by Cristian Scatena, Roberto Ravasio, Paola Raimondo, Mario Giuliano

“…OBJECTIVE: To estimate the budget impact determined by the adoption of two different diagnostic strategies, SP142 assay or 22C3 assay, in the identification…”
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Association of XRCC3 rs1799794 polymorphism with survival of glioblastoma multiforme patients treated with combined radio-chemotherapy by Pasqualetti, Francesco, Gonnelli, Alessandra, Orlandi, Paola, Palladino, Eleonora, Giannini, Noemi, Gadducci, Giovanni, Mattioni, Roberto, Montrone, Sabrina, Calistri, Elisa, Mazzanti, Chiara Maria, Franceschi, Sara, Ortenzi, Valerio, Scatena, Cristian, Zavaglia, Katia, Fanelli, Giuseppe Nicolo, Morganti, Riccardo, Santonocito, Orazio, Bocci, Guido, Naccarato, Giuseppe Antonio, Paiar, Fabiola

“…Summary This study reports the results of a monocentric prospective analysis conducted with the aim of evaluating the impact of XRCC1 rs25487 , XRCC3 rs861539…”
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Correction to: Association of XRCC3 rs1799794 polymorphism with survival of glioblastoma multiforme patients treated with combined radio-chemotherapy by Pasqualetti, Francesco, Gonnelli, Alessandra, Orlandi, Paola, Palladino, Eleonora, Giannini, Noemi, Gadducci, Giovanni, Mattioni, Roberto, Montrone, Sabrina, Calistri, Elisa, Mazzanti, Chiara Maria, Franceschi, Sara, Ortenzi, Valerio, Scatena, Cristian, Zavaglia, Katia, Fanelli, Giuseppe Nicolo, Morganti, Riccardo, Santonocito, Orazio, Bocci, Guido, Naccarato, Antonio Giuseppe, Paiar, Fabiola

“…A Correction to this paper has been published: https://doi.org/10.1007/s10637-021-01097-3…”
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Dabrafenib and Trametinib prolong coagulation through the inhibition of tissue factor in BRAFv600e mutated melanoma cells in vitro by Scatena, Cristian, Franceschi, Sara, Franzini, Maria, Sanguinetti, Chiara, Romiti, Nadia, Caponi, Laura, Mandalà, Mario, Mazzanti, Chiara Maria, Naccarato, Antonio Giuseppe

“…Background Neoplastic cells promote a hypercoagulable state by the expression of cell surface proteins, such as tissue factor. In BRAFv600 mutated melanoma…”
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Sparc-Like Protein 1 Is a New Marker of Human Glioma Progression by Turtoi, Andrei, Musmeci, Davide, Naccarato, Antonio Giuseppe, Scatena, Cristian, Ortenzi, Valerio, Kiss, Robert, Murtas, Daniela, Patsos, Georgios, Mazzucchelli, Gabriel, De Pauw, Edwin, Bevilacqua, Generoso, Castronovo, Vincent

“…High-grade gliomas (glioblastomas) are the most common and deadly brain tumors in adults, currently with no satisfactory treatment available. Apart from de…”
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Thrombophilic status may predict prognosis in patients with metastatic BRAFV600-mutated melanoma who are receiving BRAF inhibitors by Falanga, Anna, MD, Marchetti, Marina, PhD, Massi, Daniela, MD, Merelli, Barbara, MD, Verzeroli, Cristina, PhD, Russo, Laura, PhD, Rulli, Eliana, MSc, Tondini, Carlo, MD, Legramandi, Lorenzo, BSc, Nassini, Romina, PhD, Scatena, Cristian, MD, De Logu, Francesco, PhD, Cattaneo, Laura, MD, Mandalà, Mario, MD

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ANKRD44 Gene Silencing: A Putative Role in Trastuzumab Resistance in Her2-Like Breast Cancer by La Ferla, Marco, Lessi, Francesca, Aretini, Paolo, Pellegrini, Davide, Franceschi, Sara, Tantillo, Elena, Menicagli, Michele, Marchetti, Ivo, Scopelliti, Claudia, Civita, Prospero, De Angelis, Claudia, Diodati, Lucrezia, Bertolini, Ilaria, Roncella, Manuela, McDonnell, Liam A, Hochman, Jacob, Del Re, Marzia, Scatena, Cristian, Naccarato, Antonio G, Fontana, Andrea, Mazzanti, Chiara M

“…Trastuzumab is an effective therapeutic treatment for Her2-like breast cancer; despite this most of these tumors develop resistance to therapy due to specific…”
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