Search Results - "Crisostomo, Veronica"
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Dose-dependent improvement of cardiac function in a swine model of acute myocardial infarction after intracoronary administration of allogeneic heart-derived cells
Published in Stem cell research & therapy (31-05-2019)“…Allogeneic cardiac-derived progenitor cells (CPC) without immunosuppression could provide an effective ancillary therapy to improve cardiac function in…”
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Subxiphoid access to normal pericardium with micropuncture set: technical feasibility study in pigs
Published in Radiology (01-02-2006)“…This study was performed with approval from the ethics committee for animal research of the local government. The purpose of the study was to evaluate the…”
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Preclinical Evaluation of the Safety and Immunological Action of Allogeneic ADSC-Collagen Scaffolds in the Treatment of Chronic Ischemic Cardiomyopathy
Published in Pharmaceutics (17-08-2021)“…The use of allogeneic adipose-derived mesenchymal stromal cells (alloADSCs) represents an attractive approach for treating myocardial infarction (MI)…”
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The Measurement of Neurovegetative Activity During Anesthesia and Surgery in Swine: An Evaluation of Different Techniques
Published in Anesthesia and analgesia (01-05-2006)“…In this study we evaluated, in 10 sevoflurane-anesthetized pigs undergoing abdominal surgery, different techniques for measuring autonomic nervous system (ANS)…”
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The IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): multicenter pig study on the effect of ischemic preconditioning
Published in Basic research in cardiology (18-10-2024)“…Numerous cardioprotective interventions have been reported to reduce myocardial infarct size (IS) in pre-clinical studies. However, their translation for the…”
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Colchicine added to standard therapy further reduces fibrosis in pigs with myocardial infarction
Published in Journal of cardiovascular medicine (Hagerstown, Md.) (01-11-2023)“…Background The anti-inflammatory drug colchicine improves the outcome of patients with myocardial infarction (MI). As an intense inflammatory and fibrotic…”
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Delayed administration of allogeneic cardiac stem cell therapy for acute myocardial infarction could ameliorate adverse remodeling: experimental study in swine
Published in Journal of translational medicine (12-05-2015)“…The optimal timing of cardiac stem cells administration is still unclear. We assessed the safety of same-day and delayed (one week) delivery and the possible…”
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Development of Silk Fibroin Scaffolds for Vascular Repair
Published in Biomacromolecules (13-03-2023)“…Silk fibroin (SF) is a biocompatible natural protein with excellent mechanical characteristics. SF-based biomaterials can be structured using a number of…”
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Personalized tissue-engineered veins - long term safety, functionality and cellular transcriptome analysis in large animals
Published in Biomaterials science (30-05-2023)“…Tissue engineering is a promising methodology to produce advanced therapy medicinal products (ATMPs). We have developed personalized tissue engineered veins…”
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INTRACORONARY ADMINISTRATION OF MICROENCAPSULATED INSULIN-LIKE GROWTH FACTOR 1 IMPROVES CARDIAC FUNCTION IN A SWINE MODEL OF ACUTE MYOCARDIAL INFARCTION
Published in Journal of the American College of Cardiology (05-04-2016)“…Conclusions The IC administration of 5x10^6 IGF1 loaded MSP could impair coronary flow on the short term, although this is not reflected in cTpn, but it was…”
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The epicardial delivery of cardiosphere derived cells or their extracellular vesicles is safe but of limited value in experimental infarction
Published in Scientific reports (12-11-2021)“…The epicardial administration of therapeutics via the pericardial sac offers an attractive route, since it is minimally invasive and carries no risks of…”
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Microencapsulated Insulin-Like Growth Factor-1 therapy improves cardiac function and reduces fibrosis in a porcine acute myocardial infarction model
Published in Scientific reports (28-04-2020)“…Insulin-like growth factor-1 (IGF-1) has demonstrated beneficial effects after myocardial infarction (MI). Microencapsulation of IGF-1 could potentially…”
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Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model
Published in PloS one (11-02-2016)“…The intrapericardial delivery has been defined as an efficient method for pharmacological agent delivery. Here we hypothesize that intrapericardial…”
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Abstract 19337: Transcoronary Delivery of Allogeneic Cardiac Stem Cells Reduces Ventricular Arrhythmia Inducibility in a Post Myocardial Infarction Swine Model
Published in Circulation (New York, N.Y.) (10-11-2015)“…IntroductionPost myocardial infarction (MI) patients are at risk of scar related ventricular tachycardia (VT).HypothesisStem cell therapy reduces post-MI scar…”
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CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions
Published in Scientific reports (30-12-2019)“…Despite many cardioprotective interventions have shown to protect the heart against ischemia/reperfusion injury in the experimental setting, only few of them…”
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ALLOGENEIC CARDIAC STEM CELL ADMINISTRATION FOR ACUTE MYOCARDIAL INFARCTION. A TIMING EXPERIMENTAL STUDY IN SWINE
Published in Journal of the American College of Cardiology (01-04-2014)Get full text
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THE INTRAPERICARDIAL DELIVERY PROVIDES A SAFE AND EFFICIENT METHOD FOR MESENCHYMAL STEM CELL-BASED THERAPIES
Published in Journal of the American College of Cardiology (01-04-2014)Get full text
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