Search Results - "Crinière, E."

Temozolomide As Initial Treatment for Adults With Low-Grade Oligodendrogliomas or Oligoastrocytomas and Correlation With Chromosome 1p Deletions by HOANG-XUAN, K, CAPELLE, L, CARPENTIER, A. F, LAIGLE, F, SIMON, J. M, CORNU, P, BROËT, P, SANSON, M, DELATTRE, J. Y, KUJAS, M, TAILLIBERT, S, DUFFAU, H, LEJEUNE, J, POLIVKA, M, CRINIERE, E, MARIE, Y, MOKHTARI, K

“…To determine the response rate of low-grade oligodendroglial tumors (LGOT) to temozolomide (TMZ) as initial treatment and to evaluate the predictive value of…”
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Correlations between molecular profile and radiologic pattern in oligodendroglial tumors by LAIGLE-DONADEY, F, MARTIN-DUVERNEUIL, N, CARPENTIER, A, SANSON, M, HOANG-XUAN, K, THILLET, J, DELATTRE, J. Y, LEJEUNE, J, CRINIERE, E, CAPELLE, L, DUFFAU, H, CORNU, P, BROËT, P, KUJAS, M, MOKHTARI, K

“…To investigate possible correlations between tumor location and genetic alterations in a series of oligodendrogliomas. A series of 158 consecutive…”
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All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2 by LABUSSIERE, M, IDBAIH, A, DUCRAY, F, EL HALLANI, S, MOKHTARI, K, HOANG-XUAN, K, DELATTRE, J.-Y, SANSON, M, WANG, X.-W, MARIE, Y, BOISSELIER, B, FALET, C, PARIS, S, LAFFAIRE, J, CARPENTIER, C, CRINIERE, E

“…Recently, the gene encoding the human cytosolic NADPH-dependent isocitrate dehydrogenase (IDH1) was reported frequently mutated in gliomas. Rare mutations were…”
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Olig2 expression, GFAP, p53 and 1p loss analysis contribute to glioma subclassification by Mokhtari, K., Paris, S., Aguirre-Cruz, L., Privat, N., Crinière, E., Marie, Y., Hauw, J.-J., Kujas, M., Rowitch, D., Hoang-Xuan, K., Delattre, J.-Y., Sanson, M.

“…The expression of Olig2, a basic helix–loop–helix (bHLH) transcription factor involved in oligodendroglial specification, was investigated by…”
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Multidrug resistance-associated protein MRP1 expression in human gliomas: chemosensitization to vincristine and etoposide by indomethacin in human glioma cell lines overexpressing MRP1 by BENYAHIA, B, HUGUET, S, DECLEVES, X, MOKHTARI, K, CRINIERE, E, BERNAUDIN, J. F, SCHERRMANN, J. M, DELATTRE, J. Y

“…The 190 kDa multidrug resistance protein MRP1 is likely to be involved in the multidrug resistance phenotype of human gliomas. MRP1 expression was evaluated in…”
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α-Internexin expression identifies 1p19q codeleted gliomas by DUCRAY, F, CRINIERE, E, HOANG-XUAN, K, DELATTRE, J.-Y, SANSON, M, IDBAIH, A, MOKHTARI, K, MARIE, Y, PARIS, S, NAVARRO, S, LAIGLE-DONADEY, F, DEHAIS, C, THILLET, J

“…alpha-Internexin (INA) is a proneural gene encoding a neurofilament interacting protein that is upregulated in some gliomas, particularly oligodendrogliomas…”
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Telomerase reactivation in malignant gliomas and loss of heterozygosity on 10p15.1 by Leuraud, P, Aguirre-Cruz, L, Hoang-Xuan, K, Crinière, E, Tanguy, M-L, Golmard, J-L, Kujas, M, Delattre, J-Y, Sanson, M

“…An inhibitor of telomerase activity maps to chromosome 10p15.1. A series of 51 high-grade gliomas was analyzed for loss of heterozygosity (LOH) on chromosome…”
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Correlation between genetic alterations and growth of human malignant glioma xenografted in nude mice by LEURAUD, P, TAILLANDIER, L, POUPON, M.-F, SANSON, M, AGUIRRE-CRUZ, L, MEDIONI, J, CRINIERE, E, MARIE, Y, DUTRILLAUX, A. M, KUJAS, M, DUPREZ, A, DELATTRE, J.-Y

“…In order to develop preclinical models of malignant astrocytomas and oligodendrogliomas, a series of 54 resected gliomas (37 from oligodendroglial lineage and…”
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Epidermal growth factor receptor extracellular domain mutations in primary glioblastoma by Idbaih, A., Aimard, J., Boisselier, B., Marie, Y., Paris, S., Crinière, E., Carvalho Silva, R., Laigle-Donadey, F., Rousseau, A., Mokhtari, K., Thillet, J., Sanson, M., Hoang-Xuan, K., Delattre, J.-Y.

“…Aims: Novel missense mutations of the epidermal growth factor receptor (EGFR) extracellular domain have been recently described in a large series of…”
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A uniform activated B-cell–like immunophenotype might explain the poor prognosis of primary central nervous system lymphomas: analysis of 83 cases by Camilleri-Broët, Sophie, Crinière, Emmanuelle, Broët, Philippe, Delwail, Vincent, Mokhtari, Karima, Moreau, Anne, Kujas, Michèle, Raphaël, Martine, Iraqi, Wafae, Sautès-Fridman, Catherine, Colombat, Philippe, Hoang-Xuan, Khê, Martin, Antoine

“…Most primary central nervous system lymphomas (PCNSLs) in immunocompetent patients are diffuse large B-cell lymphomas (DLBCLs), characterized by poor…”
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Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis by Laffaire, Julien, Everhard, Sibille, Idbaih, Ahmed, Crinière, Emmanuelle, Marie, Yannick, de Reyniès, Aurelien, Schiappa, Renaud, Mokhtari, Karima, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves, Thillet, Joëlle, Ducray, François

“…Extensive genomic and gene expression studies have been performed in gliomas, but the epigenetic alterations that characterize different subtypes of gliomas…”
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Prognostic impact of molecular markers in a series of 220 primary glioblastomas by Houillier, Caroline, Lejeune, Julie, Benouaich‐Amiel, Alexandra, Laigle‐Donadey, Florence, Criniere, Emmanuelle, Mokhtari, Karima, Thillet, Joelle, Delattre, Jean‐Yves, Hoang‐Xuan, Khe, Sanson, Marc

“…BACKGROUND In contrast to oligodendrogliomas, molecular predictors of prognosis have not been consistently found in glioblastomas. However, genetic studies…”
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Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas by HESSON, Luke, BIECHE, Ivan, KREX, Dietmar, CRINIERE, Emmanuelle, HOANG-XUAN, Khê, MAHER, Eamonn R, LATIF, Farida

“…RASSF1A is a major tumor suppressor gene located at 3p21.3. We investigated the role of aberrant promoter region hypermethylation of RASSF1A in a large series…”
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Chromosome 1p loss: A favorable prognostic factor in low-grade gliomas by Kujas, Michèle, Lejeune, Julie, Benouaich-Amiel, Alexandra, Crinière, Emmanuelle, Laigle-Donadey, Florence, Marie, Yannick, Mokhtari, Karima, Polivka, Marc, Bernier, Michèle, Chretien, Fabrice, Couvelard, Anne, Capelle, Laurent, Duffau, Hugues, Cornu, Philippe, Broët, Philippe, Thillet, Joëlle, Carpentier, Antoine F., Sanson, Marc, Hoang-Xuan, Khê, Delattre, Jean-Yves

“…Search for loss of heterozygosity on chromosomes 1p, 9p, 10q, and 19q, epidermal growth factor receptor (EGFR) gene amplification, and p53 expression was…”
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Chromosome 9p and 10q losses predict unfavorable outcome in low-grade gliomas by Houillier, Caroline, Mokhtari, Karima, Carpentier, Catherine, Crinière, Emmanuelle, Marie, Yannick, Rousseau, Audrey, Kaloshi, Gentian, Dehais, Caroline, Laffaire, Julien, Laigle-Donadey, Florence, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves

“…The loss of chromosomes 1p-19q is the only prognostic molecular alteration identified in low-grade gliomas (LGGs) to date. Search for loss of heterozygosity…”
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Lymphomes intracrâniens du sujet immunocompétent by Louis, E., Camilleri-Broët, S., Crinière, E., Hoang-Xuan, K.

“…Les lymphomes intracrâniens sont représentés dans leur grande majorité par les lymphomes cérébraux primitifs (LCP) dont l’incidence a considérablement augmenté…”
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Gliomes de bas grade : corrélations histo-moléculaires by Kujas, M., Laigle-Donadey, F., Lejeune, J., Crinière, E., Marie, Y., Polivka, M., Mokhtari, K., Capelle, L, Delattre, J.Y.

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Distinct responses of xenografted gliomas to different alkylating agents are related to histology and genetic alterations by LEURAUD, Pascal, TAILLANDIER, Luc, SANSON, Marc, POUPON, Marie-France, MEDIONI, Jacques, AGUIRRE-CRUZ, Lucinda, CRINIERE, Emmanuelle, MARIE, Yannick, KUJAS, Michèle, GOLMARD, Jean-Louis, DUPREZ, Adrien, DELATTRE, Jean-Yves

“…A series of 12 human gliomas was established as xenografts in nude mice and used to evaluate the relationship between histology, genetic parameters, and…”
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Influence of MDM2 SNP309 alone or in combination with the TP53 R72P polymorphism in oligodendroglial tumors by Idbaih, Ahmed, Boisselier, Blandine, Marie, Yannick, Sanson, Marc, El Hallani, Soufiane, Crinière, Emmanuelle, Fourtassi, Maryam, Paris, Sophie, Carpentier, Catherine, Rousseau, Audrey, Mokhtari, Karima, Combadière, Christophe, Laigle-Donadey, Florence, Hoang-Xuan, Khê, Delattre, Jean-Yves

“…Abstract The transcription factor p53 and its negative regulator MDM2 are pivotal in normal and cancer cells biology. Recently, a functional single-nucleotide…”
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Loss of 22q chromosome is related to glioma progression and loss of 10q by LAIGLE-DONADEY, Florence, CRINIERE, Emmanuelle, BENOUAICH, Alexandra, LESUEUR, Emmanuelle, MOKHTARI, Karima, KHE, Hoang-Xuan, SANSON, Marc

“…Loss of heterozygosity (LOH) of chromosome 22q has been investigated in 160 gliomas. LOH at one or more microsatellite increased with increasing grade of the…”
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