Search Results - "Crimi, Nunzio"
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Misdiagnosis of asthma and COPD and underuse of spirometry in primary care unselected patients
Published in Respiratory medicine (01-09-2018)“…The diagnosis of both asthma and chronic obstructive pulmonary disease (COPD) consists of a combination of classical symptoms and signs, and the evidence of…”
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2
Impact of chronic obstructive pulmonary disease on passive viscoelastic components of the musculoarticular system
Published in Scientific reports (10-09-2021)“…Chronic obstructive pulmonary disease (COPD) produces skeletal muscle atrophy and weakness, leading to impairments of exercise performance. The mechanical work…”
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3
Practical considerations for spirometry during the COVID-19 outbreak: Literature review and insights
Published in Pulmonology (01-09-2021)“…As the Coronavirus disease 2019 (COVID-19) is spreading worldwide, countries are dealing with different phases of the pandemic. Lately, scientific evidence has…”
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4
Clinical and economic consequences of switching from omalizumab to mepolizumab in uncontrolled severe eosinophilic asthma
Published in Scientific reports (09-03-2021)“…Severe asthma is burdened by frequent exacerbations and use of oral corticosteroids (OCS), which worsen patients’ health and increase healthcare spending. The…”
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5
Inhibition of PI3K prevents the proliferation and differentiation of human lung fibroblasts into myofibroblasts: the role of class I P110 isoforms
Published in PloS one (03-10-2011)“…Idiopathic pulmonary fibrosis (IPF) is a progressive fibroproliferative disease characterized by an accumulation of fibroblasts and myofibroblasts in the…”
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6
Switching from omalizumab to mepolizumab: real-life experience from Southern Italy
Published in Therapeutic advances in respiratory disease (01-06-2020)“…Background: Current availability of several biologic treatments for severe asthma makes it possible to choose the most appropriate for each patient. Sometimes…”
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7
Real-life effectiveness of mepolizumab in patients with severe refractory eosinophilic asthma and multiple comorbidities
Published in The World Allergy Organization journal (01-09-2020)“…Data on mepolizumab in patients with severe eosinophilic asthma (EA) and comorbidities are needed to assess whether randomized controlled trial results are…”
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8
Real-life effects of dupilumab in patients with severe type 2 asthma, according to atopic trait and presence of chronic rhinosinusitis with nasal polyps
Published in Frontiers in immunology (30-03-2023)“…The efficacy of dupilumab as biological treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) depends on its ability to inhibit the…”
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9
Rescue Use of Beclomethasone and Albuterol in a Single Inhaler for Mild Asthma
Published in The New England journal of medicine (17-05-2007)“…Patients with mild persistent asthma are often advised to use inhaled corticosteroids on a regular schedule. In this trial, such patients treated themselves…”
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10
Effectiveness and safety of anti-IL-5/Rα biologics in eosinophilic granulomatosis with polyangiitis: a two-year multicenter observational study
Published in Frontiers in immunology (30-06-2023)“…Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare vasculitis characterized by asthma, systemic manifestations, and blood and tissue eosinophilia…”
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11
Mediterranean Diet and Particulate Matter Exposure Are Associated With LINE-1 Methylation: Results From a Cross-Sectional Study in Women
Published in Frontiers in genetics (30-10-2018)“…Emerging evidence suggests that air pollution increases the risk of cardiovascular disease (CVD) and metabolic disorders, adding to the global burden of…”
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12
Defining type 2 asthma and patients eligible for dupilumab in Italy: a biomarker-based analysis
Published in Clinical and molecular allergy CMA (21-05-2021)“…Abstract Background Asthma is a chronic disease characterized by airway hyperresponsiveness, inflammation and mucus production. In Type 2 asthma, two…”
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13
Acute and long-term management of severe bronchiectasis with high flow nasal therapy: A case report
Published in Monaldi archives for chest disease (04-08-2022)“…Bronchiectasis (BE) is a long-term, chronic lung condition featured by widened and scarred airways. These can alter the physiological mucociliary clearance,…”
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14
Case Report: Acute effect of benralizumab on asthma exacerbation without concomitant corticosteroid use [version 2; peer review: 2 approved]
Published in F1000 research (01-01-2020)“…Background: Monoclonal antibodies are a relatively new therapeutic option for patients with severe refractory asthma, which can be used as an add-on to…”
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15
Utility of ultrasound assessment of diaphragmatic function before and after pulmonary rehabilitation in COPD patients
Published in International journal of chronic obstructive pulmonary disease (01-01-2018)“…Pulmonary rehabilitation (PR) may improve respiratory symptoms and skeletal muscle strength in patients with COPD. We aimed to evaluate changes in ultrasound…”
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16
A Bloody Mess: An Unusual Case of Diffuse Alveolar Hemorrhage Because of Warfarin Overdose
Published in American journal of therapeutics (01-09-2016)“…We herein present the case of a patient with frank hemoptysis and hematuria, dyspnea, and cough. The patient was known to be affected by Chronic Obstructive…”
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Switch from Omalizumab to Benralizumab in Allergic Patients with Severe Eosinophilic Asthma: A Real-Life Experience from Southern Italy
Published in Biomedicines (03-12-2021)“…The wide availability of monoclonal antibodies for the add-on therapy of severe asthma currently allows for the personalization of biologic treatment by…”
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18
Omalizumab for the treatment of chronic spontaneous urticaria in clinical practice
Published in Annals of allergy, asthma, & immunology (01-12-2016)Get full text
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19
Real-world characteristics of “super-responders” to mepolizumab and benralizumab in severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis
Published in ERJ open research (01-09-2023)“…Background The current definition of severe eosinophilic asthma (SEA) super-responders to biologic treatment does not include patients with other…”
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20
The Model for Early COvid-19 Recognition (MECOR) Score: A Proof-of-Concept for a Simple and Low-Cost Tool to Recognize a Possible Viral Etiology in Community-Acquired Pneumonia Patients during COVID-19 Outbreak
Published in Diagnostics (Basel) (21-08-2020)“…This study aims to assess the peripheral blood cell count "signature" of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) to discriminate promptly…”
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