Search Results - "Crim, C"

Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results by Crim, C, Calverley, P. M. A, Anderson, J. A, Celli, B, Ferguson, G. T, Jenkins, C, Jones, P. W, Willits, L. R, Yates, J. C, Vestbo, J

“…Inhaled corticosteroids (ICS) are important in reducing exacerbation frequency associated with chronic obstructive pulmonary disease (COPD). However, little is…”
Get full text

Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) by Vestbo, J, Anderson, W, Coxson, H. O, Crim, C, Dawber, F, Edwards, L, Hagan, G, Knobil, K, Lomas, D. A, MacNee, W, Silverman, E. K, Tal-Singer, R, on behalf of ECLIPSE investigators

“…Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and not well understood. The forced expiratory volume in one second is used for the…”
Get full text

Predicting Outcomes from 6-Minute Walk Distance in Chronic Obstructive Pulmonary Disease by Spruit, Martijn A., PhD, PT, Polkey, Michael I., MB, ChB, PhD, FRCP, Celli, Bartolome, MD, Edwards, Lisa D., PhD, Watkins, Michael L., PharmD, Pinto-Plata, Victor, MD, Vestbo, Jørgen, MD, Calverley, Peter M.A., MD, Tal-Singer, Ruth, PhD, Agusti, Alvar, PhD, MD, Coxson, Harvey O., PhD, Lomas, David A., PhD, MacNee, William, MB, ChB, MD, Rennard, Stephen, MD, Silverman, Edwin K., PhD, MD, Crim, Courtney C., MD, Yates, Julie, BS, Wouters, Emiel F.M., PhD, MD

“…Abstract Background Exercise tolerance is an important clinical aspect of chronic obstructive pulmonary disease that can be easily and reliably measured with…”
Get full text

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13 by Cho, Michael H., Castaldi, Peter J., Wan, Emily S., Siedlinski, Mateusz, Hersh, Craig P., Demeo, Dawn L., Himes, Blanca E., Sylvia, Jody S., Klanderman, Barbara J., Ziniti, John P., Lange, Christoph, Litonjua, Augusto A., Sparrow, David, Regan, Elizabeth A., Make, Barry J., Hokanson, John E., Murray, Tanda, Hetmanski, Jacqueline B., Pillai, Sreekumar G., Kong, Xiangyang, Anderson, Wayne H., Tal-Singer, Ruth, Lomas, David A., Coxson, Harvey O., Edwards, Lisa D., MacNee, William, Vestbo, Jørgen, Yates, Julie C., Agusti, Alvar, Calverley, Peter M.A., Celli, Bartolome, Crim, Courtney, Rennard, Stephen, Wouters, Emiel, Bakke, Per, Gulsvik, Amund, Crapo, James D., Beaty, Terri H., Silverman, Edwin K.

“…The genetic risk factors for chronic obstructive pulmonary disease (COPD) are still largely unknown. To date, genome-wide association studies (GWASs) of…”
Get full text

FEV1 is a stronger mortality predictor than FVC in patients with moderate COPD and with an increased risk for cardiovascular disease by Bikov, A, Lange, P, Anderson, JA, Brook, R D, Calverley PMA, Celli, B R, Cowans, N J, Crim, C, Dixon, I J, Martinez, F J, Newby DE, Yates, J C, Vestbo, J

“…Purpose: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide. Impaired lung function is associated with heightened…”
Get full text

Validation of the Summit Lab Score in Predicting Exacerbations of Chronic Obstructive Pulmonary Disease Among Individuals with High Arterial Stiffness by Horne, Benjamin D, Ali, Rehan, Midwinter, Dawn, Scott-Wilson, Catherine, Crim, Courtney, Miller, Bruce E, Rubin, David B

“…The presence of cardiovascular (CV) risk factors and CV disease in patients with chronic obstructive pulmonary disease (COPD) leads to worse outcomes. A number…”
Get full text

Efficacy and safety of fluticasone furoate/vilanterol or tiotropium in subjects with COPD at cardiovascular risk by Covelli, Henry, Pek, Bonavuth, Schenkenberger, Isabelle, Scott-Wilson, Catherine, Emmett, Amanda, Crim, Courtney

“…Fluticasone furoate/vilanterol (FF/VI) is a novel, once-daily, inhaled corticosteroid/long-acting β2-agonist combination approved for the treatment of COPD and…”
Get full text

The Summit Score Stratifies Mortality and Morbidity in Chronic Obstructive Pulmonary Disease by Horne, Benjamin D, Hegewald, Matthew J, Crim, Courtney, Rea, Susan, Bair, Tami L, Blagev, Denitza P

“…Introduction: Tobacco use and other cardiovascular risk factors often accompany chronic obstructive pulmonary disease (COPD). This study derived and validated…”
Get full text

Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD by Crim, Courtney, Watkins, Michael L, Bateman, Eric D, Feldman, Gregory J, Schenkenberger, Isabelle, Kerwin, Edward M, Crawford, Catriona, Pudi, Krishna, Ho, Shuyen, Baidoo, Charlotte, Castro-Santamaria, Ramiro

“…Batefenterol is a novel bifunctional muscarinic antagonist β -agonist in development for COPD. The primary objective of this randomized, double-blind,…”
Get full text

A randomized trial of once-daily fluticasone furoate/vilanterol or vilanterol versus placebo to determine effects on arterial stiffness in COPD by Bhatt, Surya P, Dransfield, Mark T, Cockcroft, John R, Wang-Jairaj, Jie, Midwinter, Dawn A, Rubin, David B, Scott-Wilson, Catherine A, Crim, Courtney

“…Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality. Elevated arterial stiffness, measured by…”
Get full text

Predictors of pneumonia on routine chest radiographs in patients with COPD: a post hoc analysis of two 1-year randomized controlled trials by Rubin, David B, Ahmad, Harris A, O'Neal, Michael, Bennett, Sophie, Lettis, Sally, Galkin, Dmitry V, Crim, Courtney

“…Patients with COPD are at risk for life-threatening pneumonia. Although anatomical abnormalities in the thorax may predispose to pneumonia, those abnormalities…”
Get full text

Efficacy and safety of 4 weeks' treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trial by Lötvall, J, Bakke, P S, Bjermer, L, Steinshamn, S, Scott-Wilson, C, Crim, C, Sanford, L, Haumann, B

“…BackgroundFluticasone furoate/vilanterol (FF/VI) is a novel once-daily (OD) inhaled corticosteroid/long-acting β2 agonist combination in development for…”
Get full text

Increased energy requirements and changes in body composition with resistance training in older adults by Campbell, WW, Crim, MC, Young, VR, Evans, WJ

“…Body composition and the components of energy metabolism were examined in 12 men and women, aged 56–80 y, before and after 12 wk of resistance training…”
Get full text

Increased protein requirements in elderly people: new data and retrospective reassessments by Campbell, WW, Crim, MC, Dallal, GE, Young, VR, Evans, WJ

“…Dietary protein requirements of elderly people were determined by short-term nitrogen-balance techniques and using calculations recommended by the 1985 Joint…”
Get full text

Effects of High-Intensity Strength Training on Quality-of-Life Parameters in Cardiac Rehabilitation Patients by Beniamini, Yael, Rubenstein, Joel J., Zaichkowsky, Leonard D., Crim, Marilyn C.

“…Cardiac rehabilitation programs have not consistently been shown to improve the psychological well being of their patients. In our study of 38 cardiac patients…”
Get full text

Elderly women accommodate to a low-protein diet with losses of body cell mass, muscle function, and immune response by Castaneda, C, Charnley, JM, Evans, WJ, Crim, MC

“…A 9-wk study of adaptation to marginal protein intakes was conducted in 12 elderly women. Subjects were randomly assigned to two groups fed a…”
Get full text

Efficacy Of Ventolin® HFA MDI Cumulative Dosing In Children <24 Months Old by Davis, A, Lincourt, W, Trivedi, R, Ellsworth, A, Crim, C

“…Efficacy parameters included rescue (additional) albuterol use and modified Tal asthma symptom score (MTASS) composite of respiratory rate, wheezing, cyanosis…”
Get full text

Fluticasone propionate/salmeterol hydrofluoroalkane via metered-dose inhaler with integrated dose counter: Performance and patient satisfaction by Sheth, K, Wasserman, R L, Lincourt, W R, Locantore, N W, Carranza-Rosenzweig, J, Crim, C

“…Currently, patients have to keep track of doses to determine when to replace their metered-dose inhalers (MDIs). This study evaluated the performance and…”
Get more information

Cardiac Safety of Ventolin® HFA in Children <48 Months Old by Hedrick, J, Davis, A, Lincourt, W, Trivedi, R, Ellsworth, A, Crim, C

“…Ventolin 90mcg or 180mcg administered TID showed no significant changes in QT, QTc or PR interval, QRS duration and heart rate in this population…”
Get full text

Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome by GREGORY, T. J, LONGMORE, W. J, MOXLEY, M. A, WHITSETT, J. A, REED, C. R, FOWLER, A. A, HUDSON, L. D, MAUNDER, R. J, CRIM, C, HYERS, T. M

“…Acute Respiratory Distress Syndrome (ARDS) is characterized by lung injury and damage to the alveolar type II cells. This study sought to determine if…”
Get full text