Search Results - "Crilly, E."

Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist by Crilly, Stephanie E, Ko, Wooree, Weinberg, Zara Y, Puthenveedu, Manojkumar A

“…The prevailing model for the variety in drug responses is that they stabilize distinct active states of their G protein-coupled receptor (GPCR) targets,…”
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A multicentre review of the direct-access mammography programme in Ireland for women with breast pain by Geoghegan, C, Horan, M, Crilly, E, Kelly, A, Lyons, R, Geoghegan, L, Duke, D, Sweeney, L, McCartan, D, O'Keeffe, S

“…To assess the current use of the direct access mammography pathway for breast pain and the rate of breast cancer detection in this patient cohort. A…”
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Compartmentalized GPCR Signaling from Intracellular Membranes by Crilly, Stephanie E., Puthenveedu, Manojkumar A.

“…G protein-coupled receptors (GPCRs) are integral membrane proteins that transduce a wide array of inputs including light, ions, hormones, and neurotransmitters…”
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Prevalence and predictors of loss to follow‐up in young adults with mild haemophilia by Sun, H. (L.), McIntosh, K., Woo, C., Crilly, E., Bartholomew, C., Gue, D., De Marchi, L., Squire, S., Silva, A., Yang, M., Wu, J. K., Jackson, S.

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Combinatorial expression of GPCR isoforms affects signalling and drug responses by Marti-Solano, Maria, Crilly, Stephanie E., Malinverni, Duccio, Munk, Christian, Harris, Matthew, Pearce, Abigail, Quon, Tezz, Mackenzie, Amanda E., Wang, Xusheng, Peng, Junmin, Tobin, Andrew B., Ladds, Graham, Milligan, Graeme, Gloriam, David E., Puthenveedu, Manojkumar A., Babu, M. Madan

“…G-protein-coupled receptors (GPCRs) are membrane proteins that modulate physiology across human tissues in response to extracellular signals. GPCR-mediated…”
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Dual RXR motifs regulate nerve growth factor-mediated intracellular retention of the delta opioid receptor by Shiwarski, Daniel J, Crilly, Stephanie E, Dates, Andrew, Puthenveedu, Manojkumar A

“…The delta opioid receptor (DOR), a physiologically relevant prototype for G protein-coupled receptors, is retained in intracellular compartments in neuronal…”
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Spatial encoding of GPCR signaling in the nervous system by Weinberg, Zara Y, Crilly, Stephanie E, Puthenveedu, Manojkumar A

“…Several GPCRs, including receptors previously thought to signal primarily from the cell surface, have been recently shown to signal from many intracellular…”
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Location-biased activation of the proton-sensor GPR65 is uncoupled from receptor trafficking by Morales Rodríguez, Loyda M, Crilly, Stephanie E, Rowe, Jacob B, Isom, Daniel G, Puthenveedu, Manojkumar A

“…The canonical view of G protein-coupled receptor (GPCR) function is that receptor trafficking is tightly coupled to signaling. GPCRs remain on the plasma…”
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Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses by Marti-Solano, Maria, Crilly, Stephanie E., Malinverni, Duccio, Munk, Christian, Harris, Matthew, Pearce, Abigail, Quon, Tezz, Mackenzie, Amanda E., Wang, Xusheng, Peng, Junmin, Tobin, Andrew B., Ladds, Graham, Milligan, Graeme, Gloriam, David E., Puthenveedu, Manojkumar A., Babu, M. Madan

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Spectrin Tetramer Formation Is Not Required for Viable Development in Drosophila by Khanna, Mansi R., Mattie, Floyd J., Browder, Kristen C., Radyk, Megan D., Crilly, Stephanie E., Bakerink, Katelyn J., Harper, Sandra L., Speicher, David W., Thomas, Graham H.

“…The dominant paradigm for spectrin function is that (αβ)2-spectrin tetramers or higher order oligomers form membrane-associated two-dimensional networks in…”
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Subcellular Location‐Dependent Activation and Signaling of the Delta‐Opioid Receptor by Crilly, Stephanie E., Weinberg, Zara Y., Ko, Wooree, Puthenveedu, Manojkumar A.

“…Abstract only…”
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Model for water transport into powdered xanthan combining gel swelling and vapor diffusion by Goerke, U, Chamberlain, A H, Crilly, E A, McDonald, P J

“…Water ingress into xanthan powder compressed to various packing densities has been studied using nuclear magnetic resonance stray field imaging (STRAFI). A…”
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Combinatorial expression of functionally distinct GPCR isoforms can diversify receptor signalling response by Marti-Solano, Maria, Crilly, Stephanie E., Malinverni, Duccio, Munk, Christian, Harris, Matthew, Pearce, Abigail, Quon, Tezz, Mackenzie, Amanda E., Wang, Xusheng, Peng, Junmin, Tobin, Andrew B., Ladds, Graham, Milligan, Graeme, Gloriam, David E., Puthenveedu, Manojkumar A., Babu, M. Madan

“…G protein-coupled receptors (GPCRs) are transmembrane proteins that modulate physiology across diverse tissues in response to extracellular signals. GPCR…”
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The Use of Transgenic Animals in the European Union: The Report and Recommendations of ECVAM Workshop 28 by Mepham, T Ben, Combes, Robert D, Balls, Michael, Barbieri, Ottavia, Blokhuis, Harry J, Costa, Patrizia, Crilly, Robert E, de Cock Buning, Tjard, Delpire, Véronique C, O'Hare, Michael J, Houdebine, Louis-Marie, van Kreijl, Coen F, van der Meer, Miriam, Reinhardt, Christoph A, Wolf, Eckhard, van Zeller, Anne-Marie

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Bioethical Issues in the Generation and Use of Transgenic Farm Animals by Mepham, T. Ben, Crilly, Robert E.

“…The use of transgenic farm animals presents many challenges to the bioethicist, not least how to analyse the ethical issues within a framework that does not…”
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An ethical analysis of the use of xenografts in human transplant surgery by Mepham, T B, Moore, C J, Crilly, R E

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The Use of Transgenic Animals in the European Union: The Report and Recommendations of ECVAM Workshop 28 by Mepham, T. Ben, Combes, Robert D., Balls, Michael, Barbieri, Ottavia, Blokhuis, Harry J., Costa, Patrizia, Crilly, Robert E., de Cock Buning, Tjard, Delpire, Véronique C., O'Hare, Michael J., Houdebine, Louis-Marie, van Kreijl, Coen F., van der Meer, Miriam, Reinhardt, Christoph A., Wolf, Eckhard, van Zeller, Anne-Marie

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Supporting relatives of adults with chronic mental illness in the community: A comparative evaluation of two groups by Mitchell, Fraser, Ralston, George, McInnes, Jane, Crilly, Elise, Anderson, Jacqueline

“…Relatives of adults with chronic mental illness are recognised as an important provider of care for this vulnerable population. Carers, alongside service…”
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Securities Regulation: Insider Status in Legal Fiction and Financial Fact. A Proposed Revision to Section 16(b) by Crilly, James E.

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Bioethical issues in the generation and use of transgenic farm animals: The Production and Use of Transgenic Animals by BEN MEPHAM, T, CRILLY, R. E

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