Search Results - "Crichton, H."

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  1. 1

    Short-term mortality and morbidity of very low-birthweight infants over 9 years at Groote Schuur Hospital, Cape Town, South Africa by Crichton, H, Tooke, L

    “…\r\nBackground\r\nWith the advancement of neonatal care there has been a decrease in mortality rates of very low-birthweight (VLBW) (≤1 500 g) infants…”
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    Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline by Crichton, James H, Dunican, Donncha S, MacLennan, Marie, Meehan, Richard R, Adams, Ian R

    “…The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the…”
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    Defects in meiotic recombination delay progression through pachytene in Tex19.1−/− mouse spermatocytes by Crichton, James H., Read, David, Adams, Ian R.

    Published in Chromosoma (01-12-2018)
    “…Recombination, synapsis, chromosome segregation and gene expression are co-ordinately regulated during meiosis to ensure successful execution of this…”
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  4. 4

    Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes by Crichton, James H, Playfoot, Christopher J, MacLennan, Marie, Read, David, Cooke, Howard J, Adams, Ian R

    Published in PLoS genetics (14-07-2017)
    “…Meiosis relies on the SPO11 endonuclease to generate the recombinogenic DNA double strand breaks (DSBs) required for homologous chromosome synapsis and…”
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    Neonatal and paediatric bloodstream infections : pathogens, antimicrobial resistance patterns and prescribing practice at Khayelitsha District Hospital, Cape Town, South Africa by Rabie, H., Crichton, H., O’Connell, N., Whitelaw, A.C., Dramowski, A.

    Published in South African medical journal (01-02-2018)
    “…Background. The epidemiology of neonatal and paediatric community-acquired and healthcare-associated bloodstream infections (BSI) at South African (SA)…”
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    Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells by Reichmann, Judith, Crichton, James H, Madej, Monika J, Taggart, Mary, Gautier, Philippe, Garcia-Perez, Jose Luis, Meehan, Richard R, Adams, Ian R

    Published in PLoS computational biology (01-04-2012)
    “…Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that…”
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    The Role of Chromatin Modifications in Progression through Mouse Meiotic Prophase by Crichton, James H., Playfoot, Christopher J., Adams, Ian R.

    Published in Journal of genetics and genomics (20-03-2014)
    “…Meiosis is a key event in gametogenesis that generates new combinations of genetic information and is required to reduce the chro- mosome content of the…”
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    An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning by Ehrmann, Ingrid, Crichton, James H, Gazzara, Matthew R, James, Katherine, Liu, Yilei, Grellscheid, Sushma Nagaraja, Curk, Tomaž, de Rooij, Dirk, Steyn, Jannetta S, Cockell, Simon, Adams, Ian R, Barash, Yoseph, Elliott, David J

    Published in eLife (24-01-2019)
    “…Male germ cells of all placental mammals express an ancient nuclear RNA binding protein of unknown function called RBMXL2. Here we find that deletion of the…”
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    Oocyte development, meiosis and aneuploidy by MacLennan, Marie, Crichton, James H., Playfoot, Christopher J., Adams, Ian R.

    Published in Seminars in cell & developmental biology (01-09-2015)
    “…Meiosis is one of the defining events in gametogenesis. Male and female germ cells both undergo one round of meiotic cell division during their development in…”
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  12. 12

    A review of published independent inquiries in England into psychiatric patient homicide, 1995-2010 by Crichton, John H.M.

    “…From 1994, individuals in England who are or who have recently been patients of mental health services and who have committed homicide should have their cases…”
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    Practical system approaches to realise the human rights to water and sanitation: results and lessons from Uganda and Cambodia by Kimbugwe, C., Sou, S., Crichton-Smith, H., Goff, F.

    Published in H2Open journal (01-01-2022)
    “…Abstract The United Nations General Assembly's 2010 legal recognition of the human rights to water and sanitation shaped approaches of many actors working to…”
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  14. 14

    Defining high, medium, and low security in forensic mental healthcare: the development of the Matrix of Security in Scotland by Crichton, John H.M.

    “…As differing levels of security in forensic mental healthcare have evolved, there has been no clear or concise agreed definition of high, medium, or low secure…”
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    Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3 by Crichton, James H., Dunce, James M., Dunne, Orla M., Salmon, Lucy J., Devenney, Paul S., Lawson, Jennifer, Adams, Ian R., Davies, Owen R.

    Published in Nature structural & molecular biology (01-02-2023)
    “…In meiosis, a supramolecular protein structure, the synaptonemal complex (SC), assembles between homologous chromosomes to facilitate their recombination…”
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    The challenge of preventing spree killings by Crichton, John H M

    Published in BMJ (Online) (19-12-2012)
    “…We know something about who perpetrates them and why, but not how to prevent them…”
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    Computational Tools for the Analysis of Meiotic Prophase I Images by Crichton, James H, Adams, Ian R

    “…Prophase I is a remarkable stage of meiotic division during which homologous chromosomes pair together and exchange DNA by meiotic recombination. Fluorescence…”
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