Search Results - "Cribb, Alastair"

Comparative efficacy of oral meloxicam and phenylbutazone in 2 experimental pain models in the horse by Banse, Heidi, Cribb, Alastair E

“…The efficacy of oral phenylbutazone [PBZ; 4.4 mg/kg body weight (BW), q12h], a non-selective non-steroidal anti-inflammatory drug (NSAID), and oral meloxicam…”
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Drug-drug interaction between cannabidiol and phenobarbital in healthy dogs by Doran, Caitlin E, McGrath, Stephanie, Bartner, Lisa R, Thomas, Breonna, Cribb, Alastair E, Gustafson, Daniel L

“…To assess drug-drug interactions between cannabidiol (CBD) and phenobarbital (PB) when simultaneously administered to healthy dogs. 9 healthy, purpose bred…”
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A Pharmacokinetic-Pharmacodynamic Study of Intravenous Midazolam and Flumazenil in Adult New Zealand White-Californian Rabbits (Oryctolagus cuniculus) by Rousseau-Blass, Frédérik, Cribb, Alastair E, Beaudry, Francis, Pang, Daniel SJ

“…Flumazenil, a competitive GABAA receptor antagonist, is commonly used in rabbits to shorten sedation or postanesthetic recovery after benzodiazepine…”
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Cisplatin, Gentamicin, and p-Aminophenol Induce Markers of Endoplasmic Reticulum Stress in the Rat Kidneys by Peyrou, Mathieu, Hanna, Paul E., Cribb, Alastair E.

“…In vitro evidence of the involvement of the endoplasmic reticulum (ER) during drug-induced renal toxicity is accumulating. ER stress and ER-mediated cell death…”
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Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines by Peyrou, Mathieu, Cribb, Alastair E.

“…The cytoprotection of LLC-PK1 cells afforded by endoplasmic reticulum (ER) stress preconditioning suggests that the ER plays an important role during…”
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Role of Polymorphic Human Cytochrome P450 Enzymes in Estrone Oxidation by CRIBB, Alastair E, KNIGHT, M. Joy, DRYER, Dagny, GUERNSEY, Judy, HENDER, Kimberly, TESCH, Marvin, SALEH, Tarek M

“…Estrogen and its metabolites are believed to play important roles in breast cancer. The influence of genetic polymorphisms in the enzymes responsible for…”
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Rethinking and re-envisioning a DVM curriculum by Cribb, Alastair

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The Endoplasmic Reticulum in Xenobiotic Toxicity by Cribb, Alastair E., Peyrou, Mathieu, Muruganandan, Shanmugam, Schneider, Laetitia

“…The endoplasmic reticulum (ER) is involved in an array of cellular functions that play important roles in xenobiotic toxicity. The ER contains the majority of…”
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Looking for answers and solutions through infectious disease research by Cribb, Alastair

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A partnership solution to a pressing primary care need by Cribb, Alastair

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Clinical research at Cummings School of Veterinary Medicine by Cribb, Alastair

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Pharmacokinetics and bioequivalence of 2 meloxicam oral dosage formulations in healthy adult horses by Vivancos, Melanie, Barker, Jessica, Engbers, Sarah, Fischer, Carrie, Frederick, Jami, Friedt, Heather, Rybicka, Joanna M, Stastny, Tereza, Banse, Heidi, Cribb, Alastair E

“…Meloxicam, a non-steroidal anti-inflammatory drug, is approved for use in horses in several countries, but an equine formulation is not available in North…”
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Calpain-Induced Endoplasmic Reticulum Stress and Cell Death following Cytotoxic Damage to Renal Cells by Muruganandan, Shanmugam, Cribb, Alastair E.

“…Calpains and endoplasmic reticulum (ER) stress have both been implicated in renal cell death following exposure to reactive chemical toxicants (RCTs)…”
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Breast cancer risk, fungicide exposure and CYP1A12A gene-environment interactions in a province-wide case control study in Prince Edward Island, Canada by Ashley-Martin, Jillian, VanLeeuwen, John, Cribb, Alastair, Andreou, Pantelis, Guernsey, Judith Read

“…Scientific certainty regarding environmental toxin-related etiologies of breast cancer, particularly among women with genetic polymorphisms in estrogen…”
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CYP17, catechol-o-methyltransferase, and glutathione transferase M1 genetic polymorphisms, lifestyle factors, and breast cancer risk in women on Prince Edward Island by Cribb, Alastair E, Joy Knight, Marion, Guernsey, Judy, Dryer, Dagny, Hender, Kimberly, Shawwa, Allam, Tesch, Marvin, Saleh, Tarek M

“…Genetic polymorphisms in enzymes controlling the formation and disposition of estrogens and their metabolites have been shown to influence breast cancer risk…”
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Systemic and pituitary pars intermedia antioxidant capacity associated with pars intermedia oxidative stress and dysfunction in horses by McFarlane, D, Cribb, A.E

“…To determine whether a deficiency in systemic or local (pars intermedia) antioxidant capacity is associated with pituitary pars intermedia oxidative stress and…”
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Sympathoexcitatory effects of estrogen in the insular cortex are mediated by GABA by Saleh, Tarek M., Connell, Barry J., Cribb, Alastair E.

“…The current investigation examined the effect of estrogen in the insular cortex (IC) on autonomic tone and cardiac baroreceptor reflex function and sought to…”
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Calpain Inhibition but not Reticulum Endoplasmic Stress Preconditioning Protects Rat Kidneys from p-Aminophenol Toxicity by Peyrou, Mathieu, Hanna, Paul E., Cribb, Alastair E.

“…p-Aminophenol (pAP, 225 mg/kg) administration to rats induced renal failure and has been associated with markers of endoplasmic reticulum (ER) stress, as well…”
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Effects of season and sample handling on measurement of plasma alpha-melanocyte-stimulating hormone concentrations in horses and ponies by McFarlane, Dianne, Donaldson, Mark T, McDonnell, Sue M, Cribb, Alastair E

“…To investigate effects of sample handling, storage, and collection time and season on plasma alpha-melanocyte-stimulating hormone (alpha-MSH) concentration in…”
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Novel non-labile covalent binding of sulfamethoxazole reactive metabolites to cultured human lymphoid cells by Summan, Mukesh, Cribb, Alastair E

“…Sulfamethoxazole (SMX) causes rare hypersensitivity syndrome reactions characterized by fever and multi-organ toxicity. Covalent binding of SMX reactive…”
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