Search Results - "Cretu, Octavian M"
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Metformin and empagliflozin modulate monoamine oxidase-related oxidative stress and improve vascular function in human mammary arteries
Published in Molecular and cellular biochemistry (01-09-2023)“…Monoamine oxidases (MAOs), mitochondrial enzymes with two isoforms, A and B, have been recently recognized as significant contributors to oxidative stress in…”
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Pancreaticoduodenectomy with Anatomical Vascular Variant in Groove Pancreatitis-A Case Report
Published in Medicina (Kaunas, Lithuania) (01-04-2024)“…Groove pancreatitis represents a chronic focal form of pancreatitis affecting the zone between the pancreatic head and the duodenal "C" loop, known as the…”
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Untargeted Metabolomics by Ultra-High-Performance Liquid Chromatography Coupled with Electrospray Ionization-Quadrupole-Time of Flight-Mass Spectrometry Analysis Identifies a Specific Metabolomic Profile in Patients with Early Chronic Kidney Disease
Published in Biomedicines (30-03-2023)“…Chronic kidney disease (CKD) has emerged as one of the most progressive diseases with increased mortality and morbidity. Metabolomics offers new insights into…”
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Liver and Pancreatic Toxicity of Endocrine-Disruptive Chemicals: Focus on Mitochondrial Dysfunction and Oxidative Stress
Published in International journal of molecular sciences (06-07-2024)“…In recent years, the worldwide epidemic of metabolic diseases, namely obesity, metabolic syndrome, diabetes and metabolic-associated fatty liver disease…”
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Placental oxidative stress and monoamine oxidase expression are increased in severe preeclampsia: a pilot study
Published in Molecular and cellular biochemistry (01-12-2022)“…Preeclampsia (PE) is the most severe complication of pregnancy with substantial burden of morbidity and mortality for mother and neonate. The increased…”
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Monoamine oxidase is a source of cardiac oxidative stress in obese rats: the beneficial role of metformin
Published in Molecular and cellular biochemistry (2023)“…Diet-induced metabolic diseases, such as obesity, metabolic syndrome, and type 2 diabetes (T2DM) are the global threatening epidemics that share cardiovascular…”
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Impairment of mitochondrial respiration in platelets and placentas: a pilot study in preeclamptic pregnancies
Published in Molecular and cellular biochemistry (01-07-2022)“…Preeclampsia (PE) is a major complication of pregnancy with partially elucidated pathophysiology. Placental mitochondrial dysfunction has been increasingly…”
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Metformin alleviates monoamine oxidase-related vascular oxidative stress and endothelial dysfunction in rats with diet-induced obesity
Published in Molecular and cellular biochemistry (01-11-2021)“…In the past decade, monoamine oxidase (MAO) with 2 isoforms, MAO-A and B, has emerged as an important source of mitochondrial reactive oxygen species (ROS) in…”
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Deregulated profiles of urinary microRNAs may explain podocyte injury and proximal tubule dysfunction in normoalbuminuric patients with type 2 diabetes mellitus
Published in Journal of investigative medicine (01-04-2018)“…MicroRNAs (miRNAs) are short non-coding RNA species that are important post-transcriptional regulators of gene expression. The aim of the study was to…”
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Urinary proteins detected using modern proteomics intervene in early type 2 diabetic kidney disease – a pilot study
Published in Biomarkers in medicine (01-11-2020)“…An advanced proteomics platform for protein biomarker discovery in diabetic chronic kidney disease (DKD) was developed, validated and implemented. Three Type 2…”
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Long noncoding RNAs may impact podocytes and proximal tubule function through modulating miRNAs expression in Early Diabetic Kidney Disease of Type 2 Diabetes Mellitus patients
Published in International journal of medical sciences (01-01-2021)“…Long noncoding RNAs (lncRNAs) play key roles in the pathophysiology of DKD involving actions of microRNAs (miRNAs). The aims of the study were to establish the…”
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12
Pancreaticoduodenectomy with Anatomical Vascular Variant in Groove Pancreatitis-A Case Report
Published in Medicina (Kaunas, Lithuania) (12-04-2024)“…Groove pancreatitis represents a chronic focal form of pancreatitis affecting the zone between the pancreatic head and the duodenal "C" loop, known as the…”
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