Search Results - "Cressman, Drew E"

Liver Failure and Defective Hepatocyte Regeneration in Interleukin-6-Deficient Mice by Cressman, Drew E., Greenbaum, Linda E., DeAngelis, Robert A., Ciliberto, Gennaro, Furth, Emma E., Poli, Valeria, Taub, Rebecca

“…Liver regeneration stimulated by a loss of liver mass leads to hepatocyte and nonparenchymal cell proliferation and rapid restoration of liver parenchyma. Mice…”
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Mitogen-activated Protein Kinase ERK1/2 Regulates the Class II Transactivator by Voong, Lilien N., Slater, Allison R., Kratovac, Sebila, Cressman, Drew E.

“…The expression of major histocompatibility class II genes is necessary for proper antigen presentation and induction of an immune response. This expression is…”
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Identification of a nuclear export sequence in the MHC CIITA by Chiu, Emily, Gold, Theresa, Fettig, Veronica, LeVasseur, Michael T, Cressman, Drew E

“…Initiation of an immune response through expression of MHC class II and related genes is under the control of the CIITA. Normally found in both the cytoplasm…”
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GTP Binding by Class II Transactivator: Role in Nuclear Import by Harton, Jonathan A., Cressman, Drew E., Chin, Keh-Chuang, Der, Channing J., Jenny P.-Y. Ting

“…Class II transactivator (CIITA) is a global transcriptional coactivator of human leukocyte antigen-D (HLA-D) genes. CIITA contains motifs similar to guanosine…”
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Normal liver regeneration in p50/nuclear factor κB1 knockout mice by DeAngelis, Robert A., Kovalovich, Kellen, Cressman, Drew E., Taub, Rebecca

“…Nuclear factor κB (NF-κB) is rapidly activated during liver regeneration following partial hepatectomy or carbon tetrachloride (CCl4)-mediated liver injury and…”
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Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains by Linhoff, Michael W., Harton, Jonathan A., Cressman, Drew E., Martin, Brian K., Ting, Jenny Pan-Yun

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Serine Residues 286, 288, and 293 within the CIITA: A Mechanism for Down-Regulating CIITA Activity through Phosphorylation by Greer, Susanna F, Harton, Jonathan A, Linhoff, Michael W, Janczak, Christin A, Ting, Jenny P.-Y, Cressman, Drew E

“…CIITA is the primary factor activating the expression of the class II MHC genes necessary for the exogenous pathway of Ag processing and presentation. Strict…”
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Mechanisms of Nuclear Import and Export That Control the Subcellular Localization of Class II Transactivator by Cressman, Drew E, O'Connor, William J, Greer, Susanna F, Zhu, Xin-Sheng, Ting, Jenny P.-Y

“…The presence of the class II transactivator (CIITA) activates the transcription of all MHC class II genes. Previously, we reported that deletion of a…”
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A Defect in the Nuclear Translocation of CIITA Causes a Form of Type II Bare Lymphocyte Syndrome by Cressman, Drew E, Chin, Keh-Chuang, Taxman, Debra J, Ting, Jenny P.-Y

“…The severe immunodeficiency type II bare lymphocyte syndrome (BLS) lacks class II MHC gene transcription. One defect from a complementation group A type II BLS…”
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Rapid activation of the Stat3 transcription complex in liver regeneration by Cressman, D E, Diamond, R H, Taub, R

“…Liver regeneration in response to partial hepatectomy is a physiological growth response observed in the intact animal. Understanding the early signals that…”
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CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy by Greenbaum, L E, Li, W, Cressman, D E, Peng, Y, Ciliberto, G, Poli, V, Taub, R

“…After two-thirds hepatectomy, normally quiescent liver cells are stimulated to reenter the cell cycle and proliferate to restore the original liver mass. The…”
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Rapid activation of post-hepatectomy factor/nuclear factor kappa B in hepatocytes, a primary response in the regenerating liver by Cressman, D E, Greenbaum, L E, Haber, B A, Taub, R

“…The liver represents one of the few organs in the intact animal that has the capacity to regenerate following injury or partial hepatectomy. One of the…”
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PRL-1, a unique nuclear protein tyrosine phosphatase, affects cell growth by DIAMOND, R. H, CRESSMAN, D. E, LAZ, T. M, ABRAMS, C. S, TAUB, R

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Identification of class II transcriptional activator-induced genes by representational difference analysis: discoordinate regulation of the DN alpha/DO beta heterodimer by Taxman, D J, Cressman, D E, Ting, J P

“…Class II transcriptional activator (CIITA) is a master regulator of MHC class II genes, including DR, DP, and DQ, and MHC class II-associated genes DM and…”
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Coexistence of C/EBP alpha, beta, growth-induced proteins and DNA synthesis in hepatocytes during liver regeneration. Implications for maintenance of the differentiated state during liver growth by Greenbaum, L E, Cressman, D E, Haber, B A, Taub, R

“…During the period of rapid cell growth which follows a two-thirds partial hepatectomy, the liver is able to compensate for the acute loss of two-thirds of its…”
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Rapid induction in regenerating liver of RL/IF-1 (an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex by TEWARI, M, DOBRZANSKI, P, MOHN, K. L, CRESSMAN, D. E, JUI-CHOU HSU, BRAVO, R, TAUB, R

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Increased expression of cytokine-induced neutrophil chemoattractant in septic rat liver by Deutschman, C S, Haber, B A, Andrejko, K, Cressman, D E, Harrison, R, Elenko, E, Taub, R

“…Hepatocellular dysfunction in sepsis may be neutrophil mediated. We therefore tested the hypothesis that sepsis-induced neutrophil accumulation is associated…”
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I kappa B alpha can localize in the nucleus but shows no direct transactivation potential by Cressman, D E, Taub, R

“…Although I kappa B is a cytoplasmic inhibitor of NF-kappa B and c-Rel that prevents nuclear translocation of NF-kappa B, some forms of I kappa B have been…”
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Physiologic turnover of nuclear factor kappa B by nuclear proteolysis by Cressman, D E, Taub, R

“…Regenerating liver is a physiologic animal system in which p50/p65 nuclear factor kappa B (NF-kappa B) DNA binding activity is induced and rapidly disappears…”
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Identification of Class II Transcriptional Activator-Induced Genes by Representational Difference Analysis: Discoordinate Regulation of the DN{alpha}/DO{beta} Heterodimer by Taxman, Debra J, Cressman, Drew E, Ting, Jenny P.-Y

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