Hematopoietic and Nitrogen-Sparing Effect of Preparations from Hog Gastric Mucosa with High Content of Blood Group Substances

A mucin fraction with high content of A and H blood group substances was obtained from hog gastric mucosa. This fraction administered per os together with vitamin B12 in rats made anemic by phenylhydrazine injection shows a significant effect on the hematologic response in comparison with the animal...

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Bibliographic Details
Published in:	Blood Vol. 13; no. 2; pp. 156 - 161
Main Authors:	Cresseri, Angelo, Cantone, Aurelio, Piccinini, Franco, Capraro, Vittorio
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-02-1958
Subjects:	Anemia Blood Group Antigens Gastric Mucins - pharmacology Gastric Mucosa Hematopoiesis Hematopoietic System Nitrogen - metabolism Old Medline ANEMIA/experimental BLOOD GROUPS HEMOPOIESIS GASTRIC MUCIN/effects NITROGEN/metabolism
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Summary:	A mucin fraction with high content of A and H blood group substances was obtained from hog gastric mucosa. This fraction administered per os together with vitamin B12 in rats made anemic by phenylhydrazine injection shows a significant effect on the hematologic response in comparison with the animal treated with vitamin B12 alone. The same fraction administered per os in cortisone-treated rats has also a significant nitrogen sparing action. The possible mechanisms and relationships of the observed biologic effects are briefly discussed.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0006-4971 1528-0020
DOI:	10.1182/blood.V13.2.156.156