Search Results - "Cremoux, Patricia De"
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Two types of squamous cell carcinoma of the palatine tonsil characterized by distinct etiology, molecular features and outcome
Published in Cancer letters (18-02-2008)“…Abstract To determine whether human papillomaviruses (HPV) positive tonsillar squamous cell carcinoma (SCC) represent a specific entity, we studied the…”
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Early Metabolic Response to Neoadjuvant Treatment: FDG PET/CT Criteria according to Breast Cancer Subtype
Published in Radiology (01-11-2015)“…To investigate parameters based on fluorine 18 fluorodeoxyglucose (FDG) positron emission tomographic (PET) imaging that are best correlated with pathologic…”
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Circulating Tumor Cell Detection Predicts Early Metastatic Relapse After Neoadjuvant Chemotherapy in Large Operable and Locally Advanced Breast Cancer in a Phase II Randomized Trial
Published in Clinical cancer research (01-11-2008)“…Purpose: Circulating tumor cells in blood from metastatic breast cancer patients have been reported as a surrogate marker for tumor response and shorter…”
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4
Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review
Published in Breast cancer research and treatment (01-04-2012)“…Clinicians can use biomarkers to guide therapeutic decisions in estrogen receptor positive (ER+) breast cancer. One such biomarker is cellular proliferation as…”
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5
IDH-Mutation Is a Weak Predictor of Long-Term Survival in Glioblastoma Patients
Published in PloS one (09-07-2015)“…A very small proportion of patients diagnosed with glioblastoma (GBM) survive more than 3 years. Isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations define a…”
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Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2019)“…Predictive biomarkers for tumor response to neoadjuvant chemotherapy are needed in breast cancer. This study investigates the predictive value of 280 genes…”
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Molecular profiling of patient-derived breast cancer xenografts
Published in Breast cancer research : BCR (16-01-2012)“…Identification of new therapeutic agents for breast cancer (BC) requires preclinical models that reproduce the molecular characteristics of their respective…”
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A New Model of Patient Tumor-Derived Breast Cancer Xenografts for Preclinical Assays
Published in Clinical cancer research (01-07-2007)“…Purpose: To establish a panel of human breast cancer (HBC) xenografts in immunodeficient mice suitable for pharmacologic preclinical assays. Experimental…”
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Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line
Published in Oncogene (04-03-2004)“…Mutations in the tumor-suppressor gene p53 have been associated with advanced colorectal cancer (CRC). Irinotecan (CPT-11), a DNA topoisomerase 1 inhibitor,…”
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10
Prognostic Biomarkers Used for Localised Prostate Cancer Management: A Systematic Review
Published in European urology focus (01-12-2018)“…Abstract Context Prostate cancer stratification is based on tumour size, pretreatment PSA level, and Gleason score, but it remains imperfect. Current research…”
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Estrogen receptor‐positive/human epidermal growth factor receptor 2‐negative breast tumors
Published in Cancer (01-06-2013)“…BACKGROUND The objective of this prospective study was to evaluate the ability of 18F‐fluorodeoxyglucose (18F‐FDG) positron emission tomography/computed…”
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Frequent genomic structural alterations at HPV insertion sites in cervical carcinoma
Published in The Journal of pathology (01-07-2010)“…To investigate whether integration of HPV DNA in cervical carcinoma is responsible for structural alterations of the host genome at the insertion site, a…”
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COX2/PTGS2 Expression Is Predictive of Response to Neoadjuvant Celecoxib in HER2 -negative Breast Cancer Patients
Published in Anticancer research (01-03-2018)“…The prognostic and predictive role of cyclo-oxygenase-2 (COX2) in breast cancer is still debated, and in particular, its role as a target of COX2 inhibitor…”
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Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity
Published in Breast cancer research : BCR (01-01-2007)“…Typical medullary breast carcinoma (MBC) has recently been recognized to be part of the basal-like carcinoma spectrum, a feature in agreement with the high…”
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15
HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts
Published in Breast cancer research and treatment (01-01-2015)“…Several publications have suggested that histone deacetylase inhibitors (HDACis) could reverse the repression of estrogen receptor alpha (ERα) in…”
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18FDG-PET/CT for predicting the outcome in ER+/HER2- breast cancer patients: comparison of clinicopathological parameters and PET image-derived indices including tumor texture analysis
Published in Breast cancer research : BCR (05-01-2017)“…Background This study investigated the value of some clinicopathological parameters and 18 F-fluorodeoxyglucose-positron emission tomography/computed…”
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Clinical Significance of Immunocytochemical Detection of Tumor Cells Using Digital Microscopy in Peripheral Blood and Bone Marrow of Breast Cancer Patients
Published in Clinical cancer research (15-02-2004)“…Purpose: The presence of tumor cells in bone marrow has been reported to represent an important prognostic indicator in breast cancer, but the clinical…”
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Prospective analysis of the impact of VEGF‐A gene polymorphisms on the pharmacodynamics of bevacizumab‐based therapy in metastatic breast cancer patients
Published in British journal of clinical pharmacology (01-06-2011)“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Functional polymorphisms on the VEGF‐A gene, known to be linked to cancer risk or to VEGF‐A plasma concentrations,…”
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A multicenter blinded study evaluating EGFR and KRAS mutation testing methods in the clinical non-small cell lung cancer setting--IFCT/ERMETIC2 Project Part 1: Comparison of testing methods in 20 French molecular genetic National Cancer Institute platforms
Published in The Journal of molecular diagnostics : JMD (01-01-2014)“…Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors have limited use as first-line treatment for mutated EGFR metastatic non-small cell lung…”
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Baseline Tumor 18F-FDG Uptake and Modifications After 2 Cycles of Neoadjuvant Chemotherapy Are Prognostic of Outcome in ER+/HER2- Breast Cancer
Published in The Journal of nuclear medicine (1978) (01-06-2015)“…This study investigated whether (18)F-FDG PET/CT performed at baseline and during neoadjuvant chemotherapy (NAC) was able to early depict estrogen…”
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