Search Results - "Cremers, A."
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1
Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures
Published in Osteoarthritis and cartilage (01-10-2012)“…Summary Objective Three-dimensional (3D) cultures are widely used to redifferentiate chondrocytes. However, the rationale behind the choice for 3D above…”
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2
Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit
Published in Scientific reports (14-02-2020)“…We observed an increase in methicillin-susceptible Staphylococcus aureus (MSSA) infections at a Dutch neonatal intensive care unit. Weekly neonatal MSSA…”
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3
Determinants of Ligand-Functionalized DNA Nanostructure–Cell Interactions
Published in Journal of the American Chemical Society (14-07-2021)“…Synthesis of ligand-functionalized nanomaterials with control over size, shape, and ligand orientation facilitates the design of targeted nanomedicines for…”
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4
Hypertrophic differentiation during chondrogenic differentiation of progenitor cells is stimulated by BMP-2 but suppressed by BMP-7
Published in Osteoarthritis and cartilage (01-04-2013)“…Summary Objective Bone morphogenic protein (BMP)-2 and BMP-7 are clinically approved and their recombinant proteins are used for bone tissue regenerative…”
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5
Detection of Biological Contaminants on Foods and Food Surfaces Using Laser-Induced Breakdown Spectroscopy (LIBS)
Published in Journal of agricultural and food chemistry (11-09-2013)“…The rapid detection of biological contaminants, such as Escherichia coli O157:H7 and Salmonella enterica, on foods and food-processing surfaces is important to…”
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6
Engineering a scalable and orthogonal platform for synthetic communication in mammalian cells
Published in Nature communications (02-11-2023)“…The rational design and implementation of synthetic mammalian communication systems can unravel fundamental design principles of cell communication circuits…”
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7
Emission Enhancement Mechanisms in Dual-Pulse LIBS
Published in Analytical chemistry (Washington) (01-01-2006)“…In laser-induced breakdown spectroscopy (LIBS), a high-powered laser pulse (typically 100 mJ with a pulse width of several nanoseconds) is focused to a…”
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Atypical and fulminant presentations of pneumococcal infections: A case series in a tertiary intensive care unit
Published in Netherlands journal of medicine (01-07-2020)Get full text
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9
Efficient Small-Scale Conjugation of DNA to Primary Antibodies for Multiplexed Cellular Targeting
Published in Bioconjugate chemistry (18-09-2019)“…The combination of the specificity of antibodies and the programmability of DNA nanotechnology has provided the scientific community with a powerful tool to…”
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10
Density and duration of experimental human pneumococcal carriage
Published in Clinical microbiology and infection (01-12-2014)“…The density and duration of pneumococcal carriage are considered to affect the likelihood of transmission and invasive disease. Because of its importance in…”
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11
Synovial fluid from end-stage osteoarthritis induces proliferation and fibrosis of articular chondrocytes via MAPK and RhoGTPase signaling
Published in Osteoarthritis and cartilage (01-06-2022)“…Alterations in the composition of synovial fluid have been associated with adverse effects on cartilage integrity and function. Here, we examined the…”
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Treating severe wounds in pediatrics with medical grade honey: A case series
Published in Clinical case reports (01-03-2020)“…Medical grade honey (MGH) has antimicrobial and pro‐healing properties. We here demonstrate that MGH is an easily applicable, safe, and cost‐effective approach…”
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Use of Medical-Grade Honey to Treat Clinically Infected Heel Pressure Ulcers in High-Risk Patients: A Prospective Case Series
Published in Antibiotics (Basel) (01-03-2023)“…Management of locally infected heel-pressure ulcers (HPUs) remains challenging, and given the increasing occurrence of infections resistant to antibiotic…”
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14
Diagnostic value of serum pneumococcal DNA load during invasive pneumococcal infections
Published in European journal of clinical microbiology & infectious diseases (01-07-2014)“…Detection of pneumococcal DNA in blood could be a fast alternative for blood culture in invasive pneumococcal disease (IPD). In this study we compared the…”
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15
Unravelling the Basic Calcium Phosphate crystal-dependent chondrocyte protein secretome; a role for TGF-β signaling
Published in Osteoarthritis and cartilage (01-08-2023)“…Basic Calcium Phosphate (BCP) crystals play an active role in the progression of osteoarthritis (OA). However, the cellular consequences remain largely…”
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Direct comparison of non-osteoarthritic and osteoarthritic synovial fluid-induced intracellular chondrocyte signaling and phenotype changes
Published in Osteoarthritis and cartilage (01-01-2023)“…Since the joint microenvironment and tissue homeostasis are highly dependent on synovial fluid, we aimed to compare the essential chondrocyte signaling…”
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17
The use of laser‐based diagnostics for the rapid identification of infectious agents in human blood
Published in Journal of applied microbiology (01-05-2019)“…Aims To investigate the use of a laser‐based method of detection as a potential diagnostic test for the rapid identification of infectious agents in human…”
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18
Evaluation of the Effectiveness of Medical-Grade Honey and Hypericum Perforatum Ointment on Second-Intention Healing of Full-Thickness Skin Wounds in Cats
Published in Animals (Basel) (21-12-2023)“…This study aimed to determine the effects of two topical treatments on second-intention wound healing in cats. Eight 2 × 2 cm full-thickness wounds were…”
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Two Rare Cases of Feline Toxic Epidermal Necrolysis: A Novel Therapeutic Approach With Medical-Grade Honey
Published in Case reports in veterinary medicine (2024)“…Toxic epidermal necrolysis (TEN) is an acute and life-threatening dermatological condition that is drug-induced and characterized by extensive epidermal…”
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20
Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis
Published in Osteoarthritis and cartilage (01-03-2023)“…Osteoarthritis-related cartilage extracellular matrix remodeling is dependent on changes in chondrocyte protein expression. Yet, the role of ribosomes in…”
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