Search Results - "Cremers, A"

Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures by Caron, M.M.J, Emans, P.J, Coolsen, M.M.E, Voss, L, Surtel, D.A.M, Cremers, A, van Rhijn, L.W, Welting, T.J.M

“…Summary Objective Three-dimensional (3D) cultures are widely used to redifferentiate chondrocytes. However, the rationale behind the choice for 3D above…”
Get full text

Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit by Cremers, A. J. H., Coolen, J. P. M., Bleeker-Rovers, C. P., van der Geest-Blankert, A. D. J., Haverkate, D., Hendriks, H., Henriet, S. S. V., Huynen, M. A., Kolwijck, E., Liem, D., Melchers, W. J. G., Rossen, J. W., Zoll, J., van Heijst, A., Hopman, J., Wertheim, H. F. L.

“…We observed an increase in methicillin-susceptible Staphylococcus aureus (MSSA) infections at a Dutch neonatal intensive care unit. Weekly neonatal MSSA…”
Get full text

Determinants of Ligand-Functionalized DNA Nanostructure–Cell Interactions by Cremers, Glenn A. O, Rosier, Bas J. H. M, Meijs, Ab, Tito, Nicholas B, van Duijnhoven, Sander M. J, van Eenennaam, Hans, Albertazzi, Lorenzo, de Greef, Tom F. A

“…Synthesis of ligand-functionalized nanomaterials with control over size, shape, and ligand orientation facilitates the design of targeted nanomedicines for…”
Get full text

Hypertrophic differentiation during chondrogenic differentiation of progenitor cells is stimulated by BMP-2 but suppressed by BMP-7 by Caron, M.M.J, Emans, P.J, Cremers, A, Surtel, D.A.M, Coolsen, M.M.E, van Rhijn, L.W, Welting, T.J.M

“…Summary Objective Bone morphogenic protein (BMP)-2 and BMP-7 are clinically approved and their recombinant proteins are used for bone tissue regenerative…”
Get full text

Detection of Biological Contaminants on Foods and Food Surfaces Using Laser-Induced Breakdown Spectroscopy (LIBS) by Multari, Rosalie A, Cremers, David A, Dupre, Jo Anne M, Gustafson, John E

“…The rapid detection of biological contaminants, such as Escherichia coli O157:H7 and Salmonella enterica, on foods and food-processing surfaces is important to…”
Get full text

Engineering a scalable and orthogonal platform for synthetic communication in mammalian cells by Makri Pistikou, Anna-Maria, Cremers, Glenn A. O., Nathalia, Bryan L., Meuleman, Theodorus J., Bögels, Bas W. A., Eijkens, Bruno V., de Dreu, Anne, Bezembinder, Maarten T. H., Stassen, Oscar M. J. A., Bouten, Carlijn C. V., Merkx, Maarten, Jerala, Roman, de Greef, Tom F. A.

“…The rational design and implementation of synthetic mammalian communication systems can unravel fundamental design principles of cell communication circuits…”
Get full text

Emission Enhancement Mechanisms in Dual-Pulse LIBS by Scaffidi, Jon, Angel, S. Michael, Cremers, David A

“…In laser-induced breakdown spectroscopy (LIBS), a high-powered laser pulse (typically 100 mJ with a pulse width of several nanoseconds) is focused to a…”
Get full text

Atypical and fulminant presentations of pneumococcal infections: A case series in a tertiary intensive care unit by Liesveld, J, Cremers, A J H, Meis, J, Kolwijck, E, Schouten, J

Get full text

Efficient Small-Scale Conjugation of DNA to Primary Antibodies for Multiplexed Cellular Targeting by Cremers, Glenn A. O, Rosier, Bas J. H. M, Riera Brillas, Roger, Albertazzi, Lorenzo, de Greef, Tom F. A

“…The combination of the specificity of antibodies and the programmability of DNA nanotechnology has provided the scientific community with a powerful tool to…”
Get full text

Density and duration of experimental human pneumococcal carriage by Gritzfeld, J.F., Cremers, A.J.H., Ferwerda, G., Ferreira, D.M., Kadioglu, A., Hermans, P.W.M., Gordon, S.B.

“…The density and duration of pneumococcal carriage are considered to affect the likelihood of transmission and invasive disease. Because of its importance in…”
Get full text

Synovial fluid from end-stage osteoarthritis induces proliferation and fibrosis of articular chondrocytes via MAPK and RhoGTPase signaling by Housmans, B.A.C., Neefjes, M., Surtel, D.A.M., Vitík, M., Cremers, A., van Rhijn, L.W., van der Kraan, P.M., van den Akker, G.G.H., Welting, T.J.M.

“…Alterations in the composition of synovial fluid have been associated with adverse effects on cartilage integrity and function. Here, we examined the…”
Get full text

Treating severe wounds in pediatrics with medical grade honey: A case series by Smaropoulos, Eleftherios, Cremers, Niels A. J.

“…Medical grade honey (MGH) has antimicrobial and pro‐healing properties. We here demonstrate that MGH is an easily applicable, safe, and cost‐effective approach…”
Get full text

Use of Medical-Grade Honey to Treat Clinically Infected Heel Pressure Ulcers in High-Risk Patients: A Prospective Case Series by Papanikolaou, Georgios E, Gousios, Georgios, Cremers, Niels A J

“…Management of locally infected heel-pressure ulcers (HPUs) remains challenging, and given the increasing occurrence of infections resistant to antibiotic…”
Get full text

Diagnostic value of serum pneumococcal DNA load during invasive pneumococcal infections by Cremers, A. J. H., Hagen, F., Hermans, P. W. M., Meis, J. F., Ferwerda, G.

“…Detection of pneumococcal DNA in blood could be a fast alternative for blood culture in invasive pneumococcal disease (IPD). In this study we compared the…”
Get full text

Unravelling the Basic Calcium Phosphate crystal-dependent chondrocyte protein secretome; a role for TGF-β signaling by Stassen, R.H.M.J., van den Akker, G.G.H., Surtel, D.A.M., Housmans, B.A.C., Cremers, A., Caron, M.M.J., Smagul, A., Peffers, M.J., van Rhijn, L.W., Welting, T.J.M.

“…Basic Calcium Phosphate (BCP) crystals play an active role in the progression of osteoarthritis (OA). However, the cellular consequences remain largely…”
Get full text

Direct comparison of non-osteoarthritic and osteoarthritic synovial fluid-induced intracellular chondrocyte signaling and phenotype changes by Housmans, B.A.C., van den Akker, G.G.H., Neefjes, M., Timur, U.T., Cremers, A., Peffers, M.J., Caron, M.M.J., van Rhijn, L.W., Emans, P.J., Boymans, T.A.E.J., Feczko, P.Z., van der Kraan, P.M., Welting, T.J.M.

“…Since the joint microenvironment and tissue homeostasis are highly dependent on synovial fluid, we aimed to compare the essential chondrocyte signaling…”
Get full text

The use of laser‐based diagnostics for the rapid identification of infectious agents in human blood by Multari, R.A., Cremers, D.A., Nelson, A., Karimi, Z., Young, S., Fisher, C., Duncan, R.

“…Aims To investigate the use of a laser‐based method of detection as a potential diagnostic test for the rapid identification of infectious agents in human…”
Get full text

Evaluation of the Effectiveness of Medical-Grade Honey and Hypericum Perforatum Ointment on Second-Intention Healing of Full-Thickness Skin Wounds in Cats by Chatzimisios, Kyriakos, Tsioli, Vassiliki, Brellou, Georgia D, Apostolopoulou, Emmanouela P, Angelou, Vasileia, Pratsinakis, Emmanouil D, Cremers, Niels A J, Papazoglou, Lysimachos G

“…This study aimed to determine the effects of two topical treatments on second-intention wound healing in cats. Eight 2 × 2 cm full-thickness wounds were…”
Get full text

Two Rare Cases of Feline Toxic Epidermal Necrolysis: A Novel Therapeutic Approach With Medical-Grade Honey by Peteoacă, Alexandra, Cremers, Niels A J, Peters, Linsey J F

“…Toxic epidermal necrolysis (TEN) is an acute and life-threatening dermatological condition that is drug-induced and characterized by extensive epidermal…”
Get full text

Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis by Chabronova, A., van den Akker, G.G.H., Housmans, B.A.C., Caron, M.M.J., Cremers, A., Surtel, D.A.M., Wichapong, K., Peffers, M.M.J., van Rhijn, L.W., Marchand, V., Motorin, Y., Welting, T.J.M.

“…Osteoarthritis-related cartilage extracellular matrix remodeling is dependent on changes in chondrocyte protein expression. Yet, the role of ribosomes in…”
Get full text