Search Results - "Creeth, H D J"

Maternal care boosted by paternal imprinting in mammals by Creeth, H D J, McNamara, G I, Tunster, S J, Boque-Sastre, R, Allen, B, Sumption, L, Eddy, J B, Isles, A R, John, R M

“…In mammals, mothers are the primary caregiver, programmed, in part, by hormones produced during pregnancy. High-quality maternal care is essential for the…”
Get full text

The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources by Tunster, S.J., Creeth, H.D.J., John, R.M.

“…Imprinted genes, which are expressed from a single parental allele in response to epigenetic marks first established in the germline, function in a myriad of…”
Get full text

The placental programming hypothesis: Placental endocrine insufficiency and the co-occurrence of low birth weight and maternal mood disorders by Creeth, H.D.J., John, R.M.

“…Polypeptide hormones and steroid hormones, either expressed by the placenta or dependant on the placenta for their synthesis, are key to driving adaptations in…”
Get full text

Imprinted genes influencing the quality of maternal care by Creeth, H.D.J., McNamara, G.I., Isles, A.R., John, R.M.

“…•Many gene deletions in the dam, including the imprinted genes Peg1, Peg3 and Dio3, result in maternal care deficits.•Deletion of the offspring’s…”
Get full text

Loss of offspring Peg3 reduces neonatal ultrasonic vocalizations and increases maternal anxiety in wild-type mothers by McNamara, G I, Creeth, H D J, Harrison, D J, Tansey, K E, Andrews, R M, Isles, A R, John, R M

“…Abstract Depression and anxiety are the most common mental health conditions during pregnancy and can impair the normal development of mother-infant…”
Get full text

Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta by Tunster, S.J., McNamara, G.I., Creeth, H.D.J., John, R.M.

“…Imprinted genes are expressed primarily from one parental allele by virtue of a germ line epigenetic process. Achaete-scute complex homolog 2 (Ascl2 aka Mash2)…”
Get full text

A Role for the Placenta in Programming Maternal Mood and Childhood Behavioural Disorders by Janssen, A. B., Kertes, D. A., McNamara, G. I., Braithwaite, E. C., Creeth, H. D. J., Glover, V. I., John, R. M.

“…Substantial data demonstrate that the early‐life environment, including in utero, plays a key role in later life disease. In particular, maternal stress during…”
Get full text