Search Results - "Creese, I"

Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding by Morrow, A L, Creese, I

“…[3H]Prazosin and [3H]WB4101 [2-(2,6-dimethoxyphenoxyethyl)aminomethyl-1,4 benzodioxane] have both been proposed to label alpha 1-adrenergic receptors in the…”
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Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs by Creese, I, Burt, D R, Snyder, S H

“…Tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. Clinical potencies of butyrophenones, phenothiazines,…”
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Receptor adaptations to centrally acting drugs by Creese, I, Sibley, D R

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The classification of dopamine receptors: relationship to radioligand binding by Creese, I, Sibley, D R, Hamblin, M W, Leff, S E

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Anterior pituitary dopamine receptors. Demonstration of interconvertible high and low affinity states of the D-2 dopamine receptor by Sibley, D R, De Lean, A, Creese, I

“…The interactions of dopaminergic agonists and antagonists with binding sites in bovine anterior pituitary membranes have been investigated with…”
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Comparison of two putatively selective radioligands for labeling central nervous system beta-adrenergic receptors: inadequacy of [3H]dihydroalprenolol by Riva, M A, Creese, I

“…[3H]Dihydroalprenolol ([3H]DHA) has been used extensively in receptor binding studies to measure beta-adrenergic receptors in the central nervous system…”
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Effects of chronic SCH23390 treatment on the biochemical and behavioral properties of D1 and D2 dopamine receptors: potentiated behavioral responses to a D2 dopamine agonist after selective D1 dopamine receptor upregulation by Hess, E J, Albers, L J, Le, H, Creese, I

“…Chronic treatment of rats with SCH23390 (0.5 mg/kg/day s.c.), a D1 dopamine receptor antagonist, for 21 days resulted in an increase in D1 dopamine receptors…”
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Reevaluation of the regulation of beta-adrenergic receptor binding by desipramine treatment by Riva, M A, Creese, I

“…Treatment of rats with desipramine (DMI) has been shown to down-regulate beta-adrenergic receptor-stimulated adenylate cyclase and reduce the Bmax of…”
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Differential recovery rates of rat D2 dopamine receptors as a function of aging and chronic reserpine treatment following irreversible modification: a key to receptor regulatory mechanisms by Norman, AB, Battaglia, G, Creese, I

“…The density of D2 dopamine receptors identified by 3H-spiperone binding was significantly lower in the striatum of senescent (28-month-old) than in mature…”
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Interactions of ergot alkaloids with anterior pituitary D-2 dopamine receptors by Sibley, D R, Creese, I

“…The interactions of ergot alkaloids with bovine anterior pituitary D-2 dopamine receptors have been investigated with radioligand binding techniques and…”
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Systemic 3-nitropropionic acid: long-term effects on locomotor behavior by Koutouzis, T K, Borlongan, C V, Scorcia, T, Creese, I, Cahill, D W, Freeman, T B, Sanberg, P R

“…Systemic administration of 3-nitropropionic acid (3-NP) results in striatal atrophy by irreversibly inhibiting the citric acid cycle, and thereby resulting in…”
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Chronic treatment with dopamine receptor antagonists: behavioral and pharmacologic effects on D1 and D2 dopamine receptors by Hess, EJ, Norman, AB, Creese, I

“…Rats were treated for 21 d with the selective D1 dopamine receptor antagonist SCH23390, the selective D2 dopamine receptor antagonist spiperone, the…”
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Regulation of ligand binding to pituitary D-2 dopaminergic receptors. Effects of divalent cations and functional group modification by Sibley, D R, Creese, I

“…The effects of divalent cations and protein-modifying reagents on the binding of agonist and antagonist ligands to D-2 dopaminergic receptors were studied. The…”
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Dopamine Receptor Turnover Rates in Rat Striatum are Age-Dependent by Leff, Stuart E., Gariano, Ray, Creese, Ian

“…The time course of recovery of [3H]spiperone binding in the rat striatum after a single injection of the irreversible antagonist…”
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Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in Brain by Burt, David R., Creese, Ian, Snyder, Solomon H.

“…Chronic treatment of rats with the neuroleptic drugs haloperidol, fluphenazine, and reserpine elicits a 20 to 25 percent increase in striatal dopamine receptor…”
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Differential modification of striatal D1 dopamine receptors and effector moieties by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo and in vitro by Hess, E J, Battaglia, G, Norman, A B, Creese, I

“…Both in vivo and in vitro treatments with the irreversible protein-modifying reagent, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), were used to…”
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Reducing gene expression in the brain via antisense methods by Ouagazzal, A M, Tepper, J M, Creese, I

“…This unit presents protocols that employ antisense oligodeoxynucleotides to reduce expression of target proteins in the brain. These oligonucleotides are…”
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Effects of in vivo and in vitro treatments with N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline on putative muscarinic receptor subtypes in rat brain by Norman, A B, Creese, I

“…N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) was found to irreversibly decrease the Bmax of [3H](-)-quinuclidinyl-benzilate [(-)QNB] binding in rat…”
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Stimulus-evoked changes in neostriatal dopamine levels in awake and anesthetized rats as measured by microdialysis by Tepper, J M, Creese, I, Schwartz, D H

“…The effect of medial forebrain bundle (MFB) stimulation on neostriatal dopamine levels was examined using in vivo microdialysis in urethane-anesthetized and…”
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Differential serotonin2 receptor recovery in mature and senescent rat brain after irreversible receptor modification: effect of chronic reserpine treatment by Battaglia, G, Norman, A B, Creese, I

“…We report here the differential time course of recovery of [3H]ketanserin-labeled serotonin2 (5-HT2) receptors in frontal cortex of mature (4 months old) and…”
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