Search Results - "Creek, Moire R"

A critical review of neonicotinoid insecticides for developmental neurotoxicity by Sheets, Larry P., Li, Abby A., Minnema, Daniel J., Collier, Richard H., Creek, Moire R., Peffer, Richard C.

“…A comprehensive review of published and previously unpublished studies was performed to evaluate the neonicotinoid insecticides for evidence of developmental…”
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Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans by Mallick, Pankajini, Moreau, Marjory, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung

“…Abstract To address concerns around age-related sensitivity to pyrethroids, a life-stage physiologically based pharmacokinetic (PBPK) model, supported by in…”
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Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes by Hedges, Laura, Brown, Susan, MacLeod, A. Kenneth, Moreau, Marjory, Yoon, Miyoung, Creek, Moire R., Osimitz, Thomas G., Lake, Brian G.

“…The metabolism of bifenthrin (BIF), β-cyfluthrin (CYFL), λ-cyhalothrin (CYHA), cyphenothrin (CYPH) and esfenvalerate (ESF) was studied in liver microsomes,…”
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Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation by Song, Gina, Moreau, Marjory, Efremenko, Alina, Lake, Brian G, Wu, Huali, Bruckner, James V, White, Catherine A, Osimitz, Thomas G, Creek, Moire R, Hinderliter, Paul M, Clewell, Harvey J, Yoon, Miyoung

“…Abstract An in vitro to in vivo (IVIVE) extrapolation based-physiologically based pharmacokinetic (PBPK) modeling approach was demonstrated to understand…”
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Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages by Song, Gina, Sun, Xueying, Hines, Ronald N, McCarver, D Gail, Lake, Brian G, Osimitz, Thomas G, Creek, Moire R, Clewell, Harvey J, Yoon, Miyoung

“…Predicting age-specific metabolism is important for evaluating age-related drug and chemical sensitivity. Multiple cytochrome P450s and carboxylesterase…”
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Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids by Mallick, Pankajini, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung, Moreau, Marjory

“…Abstract The assessment of potentially sensitive populations is an important application of risk assessment. To address the concern for age-related sensitivity…”
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Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats by Higgins, Larry G., Chatham, Lynsey R., Tomczynski, Sara L., MacLeod, A. Kenneth, Moreau, Marjory, Clewell, Harvey J., Yoon, Miyoung, Creek, Moire R., Osimitz, Thomas G., Lake, Brian G.

“…The objective of this study was to obtain data on pathways of absorption of the synthetic pyrethroids deltamethrin (DLM) and cis-permethrin (CPM) following…”
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Kinetics of metabolism of deltamethrin and cis- and trans-permethrin in vitro. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol by Price, Roger J., Scott, Mary P., Cantrill, Carina, Higgins, Larry G., Moreau, Marjory, Yoon, Miyoung, Clewell, Harvey J., Creek, Moire R., Osimitz, Thomas G., Houston, J. Brian, Lake, Brian G.

“…The kinetics of metabolism of deltamethrin (DLM) and cis- and trans-permethrin (CPM and TPM) was studied in male Sprague-Dawley rat and human liver microsomes…”
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Pharmacokinetics of the Antimalarial Drug, AQ-13, in Rats and Cynomolgus Macaques by Ramanathan-Girish, Sandhya, Catz, Paul, Creek, Moire R., Wu, Benjamin, Thomas, David, Krogstad, Donald J., De, Dibyendu, Mirsalis, Jon C., Green, Carol E.

“…The purpose of this study was to evaluate the bioavailability and pharmacokinetics of a new antimalarial drug, AQ-13, a structural analog of chloroquine (CQ)…”
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Synergistic Bone Marrow Toxicity of Pyrimethamine and Zidovudine in Murine in Vivo and in Vitro Models: Mechanism of Toxicity by Freund, Yvonne R., Dabbs, Jack, Creek, Moire R., Phillips, Sandra J., Tyson, Charles A., MacGregor, James T.

“…Pyrimethamine (Pyr) is commonly used for treatment of toxoplasmic encephalitis in AIDS patients; however, in two clinical studies, an increased number of…”
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