Search Results - "Crechet, F."

Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species by Bourneuf, E., Otz, P., Pausch, H., Jagannathan, V., Michot, P., Grohs, C., Piton, G., Ammermüller, S., Deloche, M.-C., Fritz, S., Leclerc, H., Péchoux, C., Boukadiri, A., Hozé, C., Saintilan, R., Créchet, F., Mosca, M., Segelke, D., Guillaume, F., Bouet, S., Baur, A., Vasilescu, A., Genestout, L., Thomas, A., Allais-Bonnet, A., Rocha, D., Colle, M.-A., Klopp, C., Esquerré, D., Wurmser, C., Flisikowski, K., Schwarzenbacher, H., Burgstaller, J., Brügmann, M., Dietschi, E., Rudolph, N., Freick, M., Barbey, S., Fayolle, G., Danchin-Burge, C., Schibler, L., Bed’Hom, B., Hayes, B. J., Daetwyler, H. D., Fries, R., Boichard, D., Pin, D., Drögemüller, C., Capitan, A.

“…In humans, the clinical and molecular characterization of sporadic syndromes is often hindered by the small number of patients and the difficulty in developing…”
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KIT and melanoma predisposition in pigs: sequence variants and association analysis by Fernández‐Rodríguez, A, Estellé, J, Blin, A, Muñoz, M, Créchet, F, Demenais, F, Vincent‐Naulleau, S, Bourneuf, E

“…KIT mutations have been detected in different cancer subtypes, including melanoma. The gene also has been extensively studied in farm animals for its prominent…”
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Opposite regulation of tenascin-C and tenascin-X in MeLiM swine heritable cutaneous malignant melanoma by Geffrotin, C, Horak, V, Créchet, F, Tricaud, Y, Lethias, C, Vincent-Naulleau, S, Vielh, P

“…Interactions between tumour cells and surrounding extracellular matrix (ECM) influence the growth of tumour cells and their ability to metastasise. It is thus…”
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Coactivation of AP-1 activity and TGF-β1 gene expression in the stress response of normal skin cells to ionizing radiation by MARTIN, M, VOZENIN, M.-C, GAULT, N, CRECHET, F, PFARR, C. M, LEFAIX, J.-L

“…Activation of the AP-1 transcription factor and TGF-β1 growth factor by ionizing radiation was studied both in vivo in pig skin, and in vitro in human…”
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Transcription from a gene desert in a melanoma porcine model by Marthey, S., Estellé, J., Blin, A., Wahlberg, P., Créchet, F., Lecardonnel, J., Tessiot, F., Rogel-Gaillard, C., Bourneuf, E.

“…The genetic mechanisms underlying cutaneous melanoma onset and progression need to be further understood to improve patients’ care. Several studies have…”
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Temporal Modulation of TGF-β1 and β-Actin Gene Expression in Pig Skin and Muscular Fibrosis after Ionizing Radiation by Martin, Michèle, Lefaix, Jean-Louis, Pinton, Philippe, Crechet, Françoise, Daburon, François

“…Although radiation-induced fibrosis has long been characterized by excess fibroblast proliferation and extracellular matrix deposition, the origin of cell…”
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Long-Term Overproduction of Collagen in Radiation-Induced Fibrosis by Remy, J., Wegrowski, J., Crechet, F., Martin, M., Daburon, F.

“…Collagen metabolism was investigated in the fibrotic tissue which developed in pig thigh muscle 6 to 15 months after acute γ irradiation. During this period,…”
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Expression of 72-kDa Gelatinase (MMP-2), Collagenase (MMP-1), and Tissue Metalloproteinase Inhibitor (TIMP) in Primary Pig Skin Fibroblast Cultures Derived from Radiation-Induced Skin Fibrosis by Lafuma, C., El Nabout, R Azzi, Crechet, F., Hovnanian, A., Martin, M.

“…In addition to producing matrix degradation for normal tissue remodeling and repair, matrix metalloproteinases (MMPs) are also involved in various pathologic…”
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Unlike Tenascin-X, Tenascin-C Is Highly Up-Regulated in Pig Cutaneous and Underlying Muscle Tissue Developing Fibrosis after Necrosis Induced by Very High-Dose Gamma Radiation by Geffrotin, C., Tricaud, Y., Crechet, F., Castelli, M., J-L. Lefaix, Vaiman, M.

“…Fibrosis is characterized by proliferation of fibroblasts and deposition of extracellular matrix (ECM). As alterations in the composition of ECM may account…”
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Effect of ionizing radiation on the expression of transforming growth factor-β by Zubova, S. G., Crechet, F., Gault, N., Danilov, A. O., Vozenin, M. K., Lefaix, J. L., Daburon, F., Martin, M., Okulov, V. B.

“…Experiments demonstrate the stimulation of transforming growth factor- beta expression in porcine skin soon after psi -irradiation in a dose of 64 Gy and in…”
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P046. High-throughput mRNA profiling of microdissected melanocytes and melanoma cells for the characterization of melanoma predisposition in a swine model by Estellé, J., Piton, G., Bevilacqua, C., Bouet, S., Bourneuf, E., Leplat, J.J., Crechet, F., Jaffrezic, F., Martin, P., Rogel-Gaillard, C., Vincent-Naulleau, S.

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Coactivation of AP-1 activity and TGF- beta 1 gene expression in the stress response of normal skin cells to ionizing radiation by Martin, M, Vozenin, M-C, Gault, N, Crechet, F, Pfarr, C M, Lefaix, J-L

“…Activation of the AP-1 transcription factor and TGF- beta 1 growth factor by ionizing radiation was studied both in vivo in pig skin, and in vitro in human…”
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Identification of five chromosomal regions involved in predisposition to melanoma by genome‐wide scan in the MeLiM swine model by Geffrotin, Claudine, Crechet, Françoise, Le Roy, Pascale, Le Chalony, Catherine, Leplat, Jean‐Jacques, Iannuccelli, Nathalie, Barbosa, Angela, Renard, Christine, Gruand, Joseph, Milan, Denis, Horak, Vratislav, Tricaud, Yves, Bouet, Stéphan, Franck, Michel, Frelat, Gérard, Vincent‐Naulleau, Silvia

“…In human familial melanoma, 3 risk susceptibility genes are already known, CDKN2A, CDK4 and MC1R. However, various observations suggest that other melanoma…”
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CDKN2A region polymorphism and genetic susceptibility to melanoma in the melim swine model of familial melanoma by Le Chalony, Catherine, Renard, Christine, Vincent‐Naulleau, Silvia, Crechet, Françoise, Leplat, Jean‐Jacques, Tricaud, Yves, Horak, Vratislav, Gruand, Joseph, Le Roy, Pascale, Frelat, Gérard, Geffrotin, Claudine

“…Some herds of miniature swine are genetically predisposed to cutaneous melanoma. To test if swine melanoma susceptibility could be linked to the CDKN2A gene,…”
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Coactivation of AP-1 activity and TGF-beta1 gene expression in the stress response of normal skin cells to ionizing radiation by Martin, M, Vozenin, M C, Gault, N, Crechet, F, Pfarr, C M, Lefaix, J L

“…Activation of the AP-1 transcription factor and TGF-beta1 growth factor by ionizing radiation was studied both in vivo in pig skin, and in vitro in human…”
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Fibronectin and collagen gene expression during in vitro ageing of pig skin fibroblasts by Martin, M, el Nabout, R, Lafuma, C, Crechet, F, Remy, J

“…The fibronectin, collagen type I, and collagen type III genes code for three major proteins of the cell matrix. The age-related alterations in their expression…”
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292Alterations of the cytokine communication network after irradiation: Example of TGF-β1 and AP-1 transcription factor in irradiated skin cells by Martin, M., Delanian, S., Lefaix, J.L., Crechet, F., Gault, N., Daburon, F.

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Preferential induction of c-fos versus c-jun protooncogene during the immediate early response of pig skin to γ-rays by MARTIN, M, PINTON, P, CRECHET, F, LEFAIX, J.-L, DABURON, F

“…The involvement of the nuclear protooncogenes c-fos and c-jun in the immediate early response of pig dermis cells was studied after in vivo gamma-irradiation…”
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Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation by Martin, M, Lefaix, J L, Pinton, P, Crechet, F, Daburon, F

“…Although radiation-induced fibrosis has long been characterized by excess fibroblast proliferation and extracellular matrix deposition, the origin of cell…”
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Effect of ionizing radiation on the expression of transforming growth factor-[beta] by Zubova, S G, Crechet, F, Gault, N, Danilov, A O, Vozenin, M K, Lefaix, J L, Daburon, F, Martin, M, Okulov, V B

“…Experiments demonstrate the stimulation of transforming growth factor-β expression in porcine skin soon after ψ-irradiation in a dose of 64 Gy and in mouse…”
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