Search Results - "Crean, Sheila"

Apolipoprotein E ε4 prevalence in Alzheimer's disease patients varies across global populations: a systematic literature review and meta-analysis by Crean, Sheila, Ward, Alex, Mercaldi, Catherine J, Collins, Jenna M, Cook, Michael N, Baker, Nicole L, Arrighi, H Michael

“…The ε4 allele of apolipoprotein E (APOE) is associated with Alzheimer's disease (AD). However, attributable risk due to APOE4 varies by region and by…”
Get more information

Efficacy and Safety of Erythropoiesis‐Stimulating Proteins in Myelodysplastic Syndrome: A Systematic Review and Meta‐Analysis by Ross, Susan D., Allen, I. Elaine, Probst, Corey A., Sercus, Brian, Crean, Sheila M., Ranganathan, Gayatri

“…Learning Objectives After completing this course, the reader will be able to: Provide the current best estimates of hemoglobin response with…”
Get full text

A safety review of topical bovine thrombin-induced generation of antibodies to bovine proteins by Ofosu, Frederick A., PhD, Crean, Sheila, MS, Reynolds, Matthew W., PhD

“…Abstract Background: Topical bovine thrombin has been used to accelerate attainment of hemostasis in the surgical setting for >60 years, and its immunogenicity…”
Get full text

Primary Care Physicians’ Perceptions of the Challenges and Barriers in the Timely Diagnosis, Treatment and Management of Fibromyalgia by Hadker, Nandini, Garg, Suchita, Chandran, Arthi B, Crean, Sheila M, McNett, Michael, Silverman, Stuart L

“…OBJECTIVES: To describe beliefs and practice patterns of primary care physicians (PCPs) providing fibromyalgia (FM) care, and to characterize differences…”
Get full text

Synthesis and Structure−Activity Relationships of Soluble 7-Substituted 3-(3,5-Dimethoxyphenyl)-1,6-naphthyridin-2-amines and Related Ureas as Dual Inhibitors of the Fibroblast Growth Factor Receptor-1 and Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinases by Thompson, Andrew M, Delaney, Amy M, Hamby, James M, Schroeder, Mel C, Spoon, Teresa A, Crean, Sheila M, Showalter, H. D. Hollis, Denny, William A

“…7-Substituted 3-aryl-1,6-naphthyridine-2,7-diamines and related 2-ureas are inhibitors of fibroblast growth factor receptor-1 (FGFR-1) and vascular endothelial…”
Get full text

A multicenter pilot study to estimate the prevalence of bovine and human coagulation antibodies in the general US population by Fareed, Jawed, Paterson, Craig A, Crean, Sheila M

“…Antibodies to bovine and human coagulation proteins have been reported to develop in some patients receiving perioperative exposure to topical bovine thrombin…”
Get more information

Bovine Thrombin Safety Reporting: An Example of Study Design and Publication Bias by Crean, Sheila, M.P.H, Michels, Shannon L., M.S.P.H, Moschella, Kevin, B.S, Reynolds, Matthew W., Ph.D

“…Background Bovine thrombin, a popular hemostat and sealant since 1945, has recently been subjected to clinical trial testing due to reformulations in 1998. We…”
Get full text

Reliable evidence of safety and efficacy of elderly patients in randomized clinical trials still needed by Crean, Sheila M, Reynolds, Matthew W, Dematto, Christin A

Get full text

Exogenous bovine thrombin as a biomarker of exposure and outcome by Crean, Sheila M, Michels, Shannon L, Reynolds, Matthew W

“…Bovine thrombin has been used for more than 60 years as a surgical hemostat and sealant. Rare postsurgical events have been attributed to antibovine thrombin…”
Get more information

A systematic literature review and meta-analysis of apolipoprotein E ϵ4 prevalence in Alzheimer patients by Arrighi, H. Michael, Crean, Sheila M, Ward, Alex, Mercaldi, Catherine J, Collins, Jenna M, Cook, Michael N, Baker, Nicole L

Get full text

Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity by Schroeder, Mel C, Hamby, James M, Connolly, Cleo J. C, Grohar, Patrick J, Winters, R. Thomas, Barvian, Mark R, Moore, Charles W, Boushelle, Stacey L, Crean, Sheila M, Kraker, Alan J, Driscoll, Denise L, Vincent, Patrick W, Elliott, William L, Lu, Gina H, Batley, Brian L, Dahring, Tawny K, Major, Terry C, Panek, Robert L, Doherty, Annette M, Showalter, H. D. Hollis

“…In continuing our search for medicinal agents to treat proliferative diseases, we have discovered 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas as a…”
Get full text

Functional Differences Between Monocyte Chemotactic Protein-1 Receptor A and Monocyte Chemotactic Protein-1 Receptor B Expressed in a Jurkat T Cell by Sanders, Sheila K, Crean, Sheila M, Boxer, Peter A, Kellner, Debra, LaRosa, Gregory J, Hunt, Stephen W., III

“…The monocyte chemotactic protein-1 (MCP-1) receptor (MCP-1R) is expressed on monocytes, a subpopulation of memory T lymphocytes, and basophils. Two…”
Get full text

Pregnancy outcomes in women with epilepsy: A systematic review and meta-analysis of published pregnancy registries and cohorts by Meador, Kimford, Reynolds, Matthew W, Crean, Sheila, Fahrbach, Kyle, Probst, Corey

“…Summary Purpose To conduct a systematic review and meta-analysis to quantify the incidence of congenital malformations (CMs) and other pregnancy outcomes as a…”
Get full text

Risk of bleeding in surgical patients treated with topical bovine thrombin sealants: a review of the literature by Reynolds, Matthew W, Clark, John, Crean, Sheila, Samudrala, Srinath

“…One of the most anticipated, but potentially serious complications during or after surgery are bleeding events. Among the many potential factors associated…”
Get full text

Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis by Ward, Alex, Crean, Sheila, Mercaldi, Catherine J, Collins, Jenna M, Boyd, Dylan, Cook, Michael N, Arrighi, H Michael

“…Population allele frequencies of apolipoprotein E (APOE) vary by geographic region. The purpose of this study is to summarize and evaluate published estimates…”
Get more information

Real-world effectiveness of anti-TNF switching in psoriatic arthritis: a systematic review of the literature by Reddy, Soumya M., Crean, Sheila, Martin, Amber L., Burns, Meghan D., Palmer, Jacqueline B.

“…Anti-tumor necrosis factors (Anti-TNFs) are a class of biologic disease-modifying anti-rheumatic drugs indicated for the treatment of moderate-to-severe…”
Get full text

A systematic review of validated methods for identifying anaphylaxis, including anaphylactic shock and angioneurotic edema, using administrative and claims data by Schneider, Gary, Kachroo, Sumesh, Jones, Natalie, Crean, Sheila, Rotella, Philip, Avetisyan, Ruzan, Reynolds, Matthew W.

“…ABSTRACT Purpose The Food and Drug Administration's Mini‐Sentinel pilot program initially aims to conduct active surveillance to refine safety signals that…”
Get full text

Topical bovine thrombin and adverse events: a review of the literature by Clark, John, Crean, Sheila, Reynolds, Matthew W.

“…ABSTRACT Objective: To review published evidence suggesting a link between topical bovine thrombin (TBT) and important adverse events (AEs). Research design…”
Get full text

A systematic review of validated methods for identifying erythema multiforme major/minor/not otherwise specified, Stevens-Johnson Syndrome, or toxic epidermal necrolysis using administrative and claims data by Schneider, Gary, Kachroo, Sumesh, Jones, Natalie, Crean, Sheila, Rotella, Philip, Avetisyan, Ruzan, Reynolds, Matthew W.

“…ABSTRACT Purpose The Food and Drug Administration's (FDA) Mini‐Sentinel pilot program aims to conduct active surveillance to refine safety signals that emerge…”
Get full text

A systematic review of validated methods for identifying hypersensitivity reactions other than anaphylaxis (fever, rash, and lymphadenopathy), using administrative and claims data by Schneider, Gary, Kachroo, Sumesh, Jones, Natalie, Crean, Sheila, Rotella, Philip, Avetisyan, Ruzan, Reynolds, Matthew W.

“…ABSTRACT Purpose The Food and Drug Administration's Mini‐Sentinel pilot program aims to conduct active surveillance to refine safety signals that emerge for…”
Get full text