Search Results - "Crawley, J.N"

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity by Ellegood, J, Anagnostou, E, Babineau, B A, Crawley, J N, Lin, L, Genestine, M, DiCicco-Bloom, E, Lai, J K Y, Foster, J A, Peñagarikano, O, Geschwind, D H, Pacey, L K, Hampson, D R, Laliberté, C L, Mills, A A, Tam, E, Osborne, L R, Kouser, M, Espinosa-Becerra, F, Xuan, Z, Powell, C M, Raznahan, A, Robins, D M, Nakai, N, Nakatani, J, Takumi, T, van Eede, M C, Kerr, T M, Muller, C, Blakely, R D, Veenstra-VanderWeele, J, Henkelman, R M, Lerch, J P

“…Autism is a heritable disorder, with over 250 associated genes identified to date, yet no single gene accounts for >1–2% of cases. The clinical presentation,…”
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AMPAKINE enhancement of social interaction in the BTBR mouse model of autism by Silverman, J.L., Oliver, C.F., Karras, M.N., Gastrell, P.T., Crawley, J.N.

“…Autism is a neurodevelopmental disorder in which the first diagnostic symptom is unusual reciprocal social interactions. Approximately half of the children…”
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Low stress reactivity and neuroendocrine factors in the BTBR T+ tf/J mouse model of autism by Silverman, J.L, Yang, M, Turner, S.M, Katz, A.M, Bell, D.B, Koenig, J.I, Crawley, J.N

“…Abstract Autism is a neurodevelopmental disorder characterized by abnormal reciprocal social interactions, communication deficits, and repetitive behaviors…”
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Hyperalgesia and increased neuropathic pain-like response in mice lacking galanin receptor 1 receptors by Blakeman, K.H., Hao, J.-X., Xu, X.-J., Jacoby, A.S., Shine, J., Crawley, J.N., Iismaa, T., Wiesenfeld-Hallin, Z.

“…The neuropeptide galanin may have a role in modulation of nociception, particularly after peripheral nerve injury. The effect of galanin is mediated by at…”
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Corrigendum to “ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice” [Neuroscience 133 (2005) 371–380] by He, B, Counts, S.E, Perez, S.E, Hohmann, J.G, Koprich, J.B, Lipton, J.W, Steiner, R.A, Crawley, J.N, Mufson, E.J

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Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines by Crawley, J N

“…A simple model system for the behavioral actions of benzodiazepines is analyzed for its dose-response predictiveness, using several benzodiazepines, and for…”
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Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine D2 pathways by Papaleo, F, Yang, F, Garcia, S, Chen, J, Lu, B, Crawley, J N, Weinberger, D R

“…Dysbindin-1 regulates D2-receptor trafficking and is implicated in schizophrenia and related cognitive abnormalities, but whether this molecular effect…”
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Cognitive abilities on transitive inference using a novel touchscreen technology for mice by Silverman, J L, Gastrell, P T, Karras, M N, Solomon, M, Crawley, J N

“…Cognitive abilities are impaired in neurodevelopmental disorders, including autism spectrum disorder (ASD) and schizophrenia. Preclinical models with strong…”
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Reduced ultrasonic vocalizations in vasopressin 1b knockout mice by Scattoni, M.L., McFarlane, H.G., Zhodzishsky, V., Caldwell, H.K., Young, W.S., Ricceri, L., Crawley, J.N.

“…The neuropeptides oxytocin and vasopressin have been implicated in rodent social and affiliative behaviors, including social bonding, parental care, social…”
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Baseline exploratory activity predicts anxiolytic responsiveness to diazepam in five mouse strains by Crawley, J N, Davis, L G

“…Inbred mouse strains showing variability in spontaneous exploratory behaviors displayed differential responsiveness to diazepam in an anxiety-related…”
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Abolition of the behavioral effects of cholecystokinin following bilateral radiofrequency lesions of the parvocellular subdivision of the nucleus tractus solitarius by Crawley, J N, Schwaber, J S

“…Cholecystokinin (CCK) has been implicated as a signal for the syndrome of satiety in a variety of species. Several lines of evidence point to a peripheral site…”
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Bilateral midbrain transections block the behavioral effects of cholecystokinin on feeding and exploration in rats by Crawley, J N, Kiss, J Z, Mezey, E

“…The mechanism by which peripherally administered cholecystokinin (CCK) reduces feeding and exploration involves a sensory feedback pathway from the…”
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Further characterization of a simple, automated exploratory model for the anxiolytic effects of benzodiazepines by Blumstein, L K, Crawley, J N

“…Anxiolytics specifically increase the number of exploratory transitions in a two-chambered model system for anxiety in mice. Characterization of parameters to…”
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Behavioral phenotyping of rodents by Crawley, J.N

“…Established methods for analyzing behavioral traits in mutant lines of mice allow researchers to understand the outcomes of genetic manipulations in the…”
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The role of galanin in feeding behavior by Crawley, J.N.

“…Galanin inhibits food consumption in satiated rats. Discovered relatively recently, galanin is a 29-amino-acid neuropeptide, not homologous with any other…”
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3D visualization of the regional differences by Ellegood, J, Anagnostou, E, Babineau, B A, Crawley, J N, Lin, L, Genestine, M, DiCicco-Bloom, E, Lai, J K Y, Foster, J A, Peñagarikano, O, Geschwind, D H, Pacey, L K, Hampson, D R, Laliberté, C L, Mills, A A, Tam, E, Osborne, L R, Kouser, M, Espinosa-Becerra, F, Xuan, Z, Powell, C M, Raznahan, A, Robins, D M, Nakai, N, Nakatani, J, Takumi, T, van Eede, M C, Kerr, T M, Muller, C, Blakely, R D, Veenstra-VanderWeele, J, Henkelman, R M, Lerch, J P

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3-Methoxy-4-hydroxyphenethyleneglycol increase in plasma after stimulation of the nucleus locus coeruleus by Crawley, J N, Hattox, S E, Maas, J W, Roth, R H

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Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice by He, B., Counts, S.E., Perez, S.E., Hohmann, J.G., Koprich, J.B., Lipton, J.W., Steiner, R.A., Crawley, J.N., Mufson, E.J.

“…The functional interactions of the neuropeptide galanin (GAL) occur through its binding to three G protein-coupled receptor subtypes: galanin receptor (GALR)…”
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Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance by Wrenn, C.C, Marriott, L.K, Kinney, J.W, Holmes, A, Wenk, G.L, Crawley, J.N

“…Galanin-overexpressing transgenic mice (GAL-tg) generated on a dopamine β-hydroxylase promoter were previously shown to express high levels of galanin mRNA in…”
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Motor deficits in fibroblast growth factor receptor-3 null mutant mice by McDonald, M P, Miller, K M, Li, C, Deng, C, Crawley, J N

“…Fibroblast growth factor receptor-3 (FGFR-3) regulates aspects of bone development. Mutations in the FGFR-3 gene (Fgfr3) in humans and mice produce vertebral…”
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