Search Results - "Crawford, Mark W."

Influence of Surgical Procedures and General Anesthesia on Child Development Before Primary School Entry Among Matched Sibling Pairs by O'Leary, James D, Janus, Magdalena, Duku, Eric, Wijeysundera, Duminda N, To, Teresa, Li, Ping, Maynes, Jason T, Faraoni, David, Crawford, Mark W

“…Substantial preclinical evidence suggests that the developing brain is susceptible to injury from anesthetic drugs. Findings from clinical studies of the…”
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Hospital admission on weekends for patients who have surgery and 30-day mortality in Ontario, Canada: A matched cohort study by O'Leary, James D, Wunsch, Hannah, Leo, Anne-Marie, Levin, David, Siddiqui, Asad, Crawford, Mark W

“…Healthcare interventions on weekends have been associated with increased mortality and adverse clinical outcomes, but these findings are inconsistent. We…”
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Cardiovascular MRI without sedation or general anesthesia using a feed-and-sleep technique in neonates and infants by Windram, Jonathan, Grosse-Wortmann, Lars, Shariat, Masoud, Greer, Mary-Louise, Crawford, Mark W., Yoo, Shi-Joon

“…Background MRI in small children generally necessitates the use of general anesthesia. Objective We describe our initial results with a new technique that we…”
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Dexamethasone as an adjuvant to peripheral nerve block by Pehora, Carolyne, Pearson, Annabel Me, Kaushal, Alka, Crawford, Mark W, Johnston, Bradley

“…Peripheral nerve block (infiltration of local anaesthetic around a nerve) is used for anaesthesia or analgesia. A limitation to its use for postoperative…”
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Efficacy of the Subtenon Block in Children Undergoing Strabismus Surgery: A Systematic Review and Meta-Analysis by Pehora, Carolyne, Johnston, Bradley, Shah, Ushma, Mireskandari, Kamiar, Ali, Asim, Crawford, Mark W.

“…To investigate the efficacy of the subtenon block in preventing postoperative complications in children undergoing strabismus surgery. Systematic review and…”
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Effect of increasing depth of propofol anesthesia on upper airway configuration in children by EVANS, Russell G, CRAWFORD, Mark W, NOSEWORTHY, Michael D, YOO, Shi-Joon

“…The upper airway tends to be obstructed during anesthesia in spontaneously breathing patients. The purpose of the current study was to determine the effect of…”
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A Population-based Study Evaluating the Association between Surgery in Early Life and Child Development at Primary School Entry by O’Leary, James D, Janus, Magdalena, Duku, Eric, Wijeysundera, Duminda N, To, Teresa, Li, Ping, Maynes, Jason T, Crawford, Mark W

“…BACKGROUND:It is unclear whether exposure to surgery in early life has long-term adverse effects on child development. The authors aimed to investigate whether…”
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Effect of propofol anesthesia and continuous positive airway pressure on upper airway size and configuration in infants by CRAWFORD, Mark W, ROHAN, Denise, MACGOWAN, Christopher K, YOO, Shi-Joon, MACPHERSON, Bruce A

“…Infants are prone to obstruction of the upper airway during general anesthesia. Continuous positive airway pressure (CPAP) is often used to prevent or treat…”
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Extent and localization of changes in upper airway caliber with varying concentrations of sevoflurane in children by CRAWFORD, Mark W, ARRICA, Mauro, MACGOWAN, Christopher K, YOO, Shi-Joon

“…Previous studies in humans suggest that inhibition of upper airway muscle activity is independent of the dose of inhalational anesthesia. Whether a…”
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Patient-Controlled Analgesia Plus Background Opioid Infusion for Postoperative Pain in Children: A Systematic Review and Meta-Analysis of Randomized Trials by Hayes, Jason, Dowling, Jeremiah J, Peliowski, Arie, Crawford, Mark W, Johnston, Bradley

“…BACKGROUND:Bolus administration of opioids via a patient-controlled analgesia (PCA) device is widely used in the postoperative pediatric population. PCA…”
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Dose-response of remifentanil for tracheal intubation in infants by CRAWFORD, Mark W, HAYES, Jason, TAN, Juliana M

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Use of Serratus Plane Block for Repair of Coarctation of Aorta: A Report of 3 Cases by Biswas, Abhijit, Luginbuehl, Igor, Szabo, Elod, Caldeira-Kulbakas, Monica, Crawford, Mark W., Everett, Tobias

“…ObjectivesThe practice of regional anesthesia techniques (thoracic, epidural, paravertebral) in pediatric cardiac surgery enhances perioperative outcomes such…”
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The novel hemoglobin-based oxygen carrier HRC 101 improves survival in murine sickle cell disease by CRAWFORD, Mark W, SHICHOR, Tal, ENGELHARDT, Thomas, ADAMSON, Gord, BELL, David, LOU CARMICHAEL, F. J, KIM, Peter C. W

“…Erythrocyte transfusion decreases morbidity in sickle cell disease, but is not without risk. Use of a hemoglobin-based oxygen carrier could offer the benefits…”
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Effect of low-dose ketamine on voltage requirement for transcranial electrical motor evoked potentials in children by Zaarour, Christian, Engelhardt, Thomas, Strantzas, Samuel, Pehora, Carolyne, Lewis, Stephen, Crawford, Mark W

“…Randomized controlled trial. OBJECTIVE.: To determine the effect of low-dose ketamine on the voltage needed to elicit maximal amplitude of the motor-evoked…”
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Minimally important difference estimates and methods: a protocol by Johnston, Bradley C, Ebrahim, Shanil, Carrasco-Labra, Alonso, Furukawa, Toshi A, Patrick, Donald L, Crawford, Mark W, Hemmelgarn, Brenda R, Schunemann, Holger J, Guyatt, Gordon H, Nesrallah, Gihad

“…IntroductionPatient-reported outcomes (PROs) are often the outcomes of greatest importance to patients. The minimally important difference (MID) provides a…”
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Effect of surgical safety checklists on pediatric surgical complications in Ontario by O'Leary, James D, Wijeysundera, Duminda N, Crawford, Mark W

“…In health care, most preventable adverse events occur in the operating room. Surgical safety checklists have become a standard of care for safe operating room…”
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L-carnitine reduces susceptibility to bupivacaine-induced cardiotoxicity: an experimental study in rats by Wong, Gail K., Pehora, Carolyne, Crawford, Mark W.

“…Background The primary aim of this study was to evaluate the effect of acute administration of L-carnitine 100 mg·kg −1 iv on susceptibility to…”
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Do clinicians understand the size of treatment effects? A randomized survey across 8 countries by Johnston, Bradley C, Alonso-Coello, Pablo, Friedrich, Jan O, Mustafa, Reem A, Tikkinen, Kari A O, Neumann, Ignacio, Vandvik, Per O, Akl, Elie A, da Costa, Bruno R, Adhikari, Neill K, Dalmau, Gemma Mas, Kosunen, Elise, Mustonen, Jukka, Crawford, Mark W, Thabane, Lehana, Guyatt, Gordon H

“…Meta-analyses of continuous outcomes typically provide enough information for decision-makers to evaluate the extent to which chance can explain apparent…”
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Ultrasonographic guidance for catheterization of the internal jugular vein via the posterior approach by Crawford, Mark W., Pehora, Carolyne

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Early postoperative patient-controlled analgesia ratio predicts 24-hour morphine consumption and pain in children undergoing scoliosis surgery by Matava, Clyde T, Crawford, Mark W, Pehora, Carolyne, Naser, Basem, McDonnell, Conor

“…The identification of patients at risk for developing severe postoperative pain and/or opioid-related side effects is difficult due to a lack of sensitive…”
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