Search Results - "Crawford, Karen"

The Image and Data Archive at the Laboratory of Neuro Imaging by Crawford, Karen L., Neu, Scott C., Toga, Arthur W.

“…The LONI Image and Data Archive (IDA)11https://ida.loni.usc.edu/. is a repository for sharing and long-term preservation of neuroimaging and biomedical…”
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Highly Efficient Knockout of a Squid Pigmentation Gene by Crawford, Karen, Diaz Quiroz, Juan F., Koenig, Kristen M., Ahuja, Namrata, Albertin, Caroline B., Rosenthal, Joshua J.C.

“…Seminal studies using squid as a model led to breakthroughs in neurobiology. The squid giant axon and synapse, for example, laid the foundation for our current…”
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Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank by Crawford, Karen, Bracher-Smith, Matthew, Owen, David, Kendall, Kimberley M, Rees, Elliott, Pardiñas, Antonio F, Einon, Mark, Escott-Price, Valentina, Walters, James T R, O'Donovan, Michael C, Owen, Michael J, Kirov, George

“…Genomic CNVs increase the risk for early-onset neurodevelopmental disorders, but their impact on medical outcomes in later life is still poorly understood. The…”
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Helping themselves and helping others: how the passage of time influences why mothers with addictions take part in research by Crawford, Karen, Russell, Lynda, Graham, Sharon, Turner, Fiona

“…Introduction Women with addiction issues are under-researched, despite previous evidence that women’s needs are less understood than men’s and that services…”
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The image and data archive at the laboratory of neuro imaging by Neu, Scott C, Crawford, Karen L, Toga, Arthur W

“…The Image and Data Archive (IDA) is a secure online resource for archiving, exploring, and sharing neuroscience data run by the Laboratory of Neuro Imaging…”
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Recruiting hard-to-reach pregnant women at high psychosocial risk: strategies and costs from a randomised controlled trial by MacLachlan, Alice, Crawford, Karen, Shinwell, Shona, Nixon, Catherine, Henderson, Marion

“…Recruiting participants to randomised controlled trials (RCTs) is often challenging, particularly when working with socially disadvantaged populations who are…”
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Sharing data in the global alzheimer's association interactive network by Neu, Scott C., Crawford, Karen L., Toga, Arthur W.

“…The Global Alzheimer's Association Interactive Network (GAAIN) aims to be a shared network of research data, analysis tools, and computational resources for…”
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Optimized axolotl (Ambystoma mexicanum) husbandry, breeding, metamorphosis, transgenesis and tamoxifen-mediated recombination by Khattak, Shahryar, Murawala, Prayag, Andreas, Heino, Kappert, Verena, Schuez, Maritta, Sandoval-Guzmán, Tatiana, Crawford, Karen, Tanaka, Elly M

“…The axolotl (Mexican salamander, Ambystoma mexicanum ) has become a very useful model organism for studying limb and spinal cord regeneration because of its…”
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The Alzheimer's Disease Neuroimaging Initiative informatics core: A decade in review by Toga, Arthur W, Crawford, Karen L

“…Abstract The Informatics Core of the Alzheimer's Disease Neuroimaging Initiative has coordinated data integration and dissemination for a continually growing…”
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Prediction and Classification of Alzheimer's Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers by Gupta, Yubraj, Lama, Ramesh Kumar, Kwon, Goo-Rak

“…Alzheimer's disease (AD), including its mild cognitive impairment (MCI) phase that may or may not progress into the AD, is the most ordinary form of dementia…”
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Standardization of analysis sets for reporting results from ADNI MRI data by Wyman, Bradley T, Harvey, Danielle J, Crawford, Karen, Bernstein, Matt A, Carmichael, Owen, Cole, Patricia E, Crane, Paul K, DeCarli, Charles, Fox, Nick C, Gunter, Jeffrey L, Hill, Derek, Killiany, Ronald J, Pachai, Chahin, Schwarz, Adam J, Schuff, Norbert, Senjem, Matthew L, Suhy, Joyce, Thompson, Paul M, Weiner, Michael, Jack, Clifford R

“…Abstract The Alzheimer’s Disease Neuroimaging Initiative (ADNI) three-dimensional T1 -weighted magnetic resonance imaging (MRI) acquisitions provide a rich…”
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Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model by Martin Flores, Nuria, Podpolny, Marina, McLeod, Faye, Workman, Isaac, Crawford, Karen, Ivanov, Dobril, Leonenko, Ganna, Escott-Price, Valentina, Salinas, Patricia C

“…Increasing evidence supports a role for deficient Wnt signaling in Alzheimer's disease (AD). Studies reveal that the secreted Wnt antagonist Dickkopf-3 (DKK3)…”
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The Global Alzheimer's Association Interactive Network by Toga, Arthur W, Neu, Scott C, Bhatt, Priya, Crawford, Karen L, Ashish, Naveen

“…Abstract Introduction The Global Alzheimer's Association Interactive Network (GAAIN) is consolidating the efforts of independent Alzheimer's disease data…”
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The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol by Vespa, Paul M., Shrestha, Vikesh, Abend, Nicholas, Agoston, Denes, Au, Alicia, Bell, Michael J., Bleck, Thomas P., Blanco, Manuel Buitrago, Claassen, Jan, Diaz-Arrastia, Ramon, Duncan, Dominique, Ellingson, Ben, Foreman, Brandon, Gilmore, Emily J., Hirsch, Lawrence, Hunn, Martin, Kamnaksh, Alaa, McArthur, David, Morokoff, Andrew, O'Brien, Terrence, O'Phelan, Kristine, Robertson, Courtney L., Rosenthal, Eric, Staba, Richard, Toga, Arthur, Willyerd, Frederick A., Zimmermann, Lara, Yam, Elisa, Martinez, Susana, Real, Courtney, Engel, Jerome

“…The Epilepsy Bioinformatics Study for Anti-epileptogenic Therapy (EpiBioS4Rx) is a longitudinal prospective observational study funded by the National…”
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The LONI QC System: A Semi-Automated, Web-Based and Freely-Available Environment for the Comprehensive Quality Control of Neuroimaging Data by Kim, Hosung, Irimia, Andrei, Hobel, Samuel M, Pogosyan, Mher, Tang, Haoteng, Petrosyan, Petros, Blanco, Rita Esquivel Castelo, Duffy, Ben A, Zhao, Lu, Crawford, Karen L, Liew, Sook-Lei, Clark, Kristi, Law, Meng, Mukherjee, Pratik, Manley, Geoffrey T, Van Horn, John D, Toga, Arthur W

“…Quantifying, controlling, and monitoring image quality is an essential prerequisite for ensuring the validity and reproducibility of many types of neuroimaging…”
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Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson’s disease by Smolensky, Luba, Amondikar, Ninad, Crawford, Karen, Neu, Scott, Kopil, Catherine M., Daeschler, Margaret, Riley, Lindsey, Brown, Ethan, Toga, Arthur W., Tanner, Caroline

“…Fox Insight is an online, longitudinal health study of people with and without Parkinson’s disease with targeted enrollment set to at least 125,000…”
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A rapid α‐synuclein seed assay of Parkinson’s disease CSF panel shows high diagnostic accuracy by Orrù, Christina D., Ma, Thong C., Hughson, Andrew G., Groveman, Bradley R., Srivastava, Ankit, Galasko, Douglas, Angers, Rachel, Downey, Patrick, Crawford, Karen, Hutten, Samantha J., Kang, Un Jung, Caughey, Byron

“…Background Assays that specifically measure α‐synuclein seeding activity in biological fluids could revolutionize the diagnosis of Parkinson’s disease. Recent…”
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The Best Services Trial (BeST?): a cluster randomised controlled trial comparing the clinical and cost-effectiveness of New Orleans Intervention Model with services as usual (SAU) for infants and young children entering care by Crawford, Karen, Fitzpatick, Bridie, McMahon, Lynn, Forde, Matt, Miller, Susanne, McConnachie, Alex, Messow, Martina, Henderson, Marion, McIntosh, Emma, Boyd, Kathleen, Ougrin, Dennis, Wilson, Phil, Watson, Nicholas, Minnis, Helen

“…Abused and neglected children are at increased risk of health problems throughout life, but negative effects may be ameliorated by nurturing family care. It is…”
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RNA sequencing of whole blood reveals early alterations in immune cells and gene expression in Parkinson's disease by Craig, David W, Hutchins, Elizabeth, Violich, Ivo, Alsop, Eric, Gibbs, J Raphael, Levy, Shawn, Robison, Madison, Prasad, Nripesh, Foroud, Tatiana, Crawford, Karen L, Toga, Arthur W, Whitsett, Timothy G, Kim, Seungchan, Casey, Bradford, Reimer, Alyssa, Hutten, Samantha J, Frasier, Mark, Kern, Fabian, Fehlman, Tobias, Keller, Andreas, Cookson, Mark R, Van Keuren-Jensen, Kendall

“…Changes in the blood-based RNA transcriptome have the potential to inform biomarkers of Parkinson's disease (PD) progression. Here we sequenced a discovery set…”
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A proteogenomic view of Parkinson’s disease causality and heterogeneity by Kaiser, Sergio, Zhang, Luqing, Mollenhauer, Brit, Jacob, Jaison, Longerich, Simonne, Del-Aguila, Jorge, Marcus, Jacob, Raghavan, Neha, Stone, David, Fagboyegun, Olumide, Galasko, Douglas, Dakna, Mohammed, Bilican, Bilada, Dovlatyan, Mary, Kostikova, Anna, Li, Jingyao, Peterson, Brant, Rotte, Michael, Sanz, Vinicius, Foroud, Tatiana, Hutten, Samantha J., Frasier, Mark, Iwaki, Hirotaka, Singleton, Andrew, Marek, Ken, Crawford, Karen, Elwood, Fiona, Messa, Mirko, Serrano-Fernandez, Pablo

“…The pathogenesis and clinical heterogeneity of Parkinson’s disease (PD) have been evaluated from molecular, pathophysiological, and clinical perspectives…”
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