Search Results - "Crawford, Diane M"
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Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes
Published in JAMA cardiology (01-12-2021)“…Early-onset atrial fibrillation (AF) can be the initial manifestation of a more serious underlying inherited cardiomyopathy or arrhythmia syndrome. To examine…”
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2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device
Published in Current controlled trials in cardiovascular medicine (28-08-2021)“…Although catheter ablation is an effective therapy for atrial fibrillation (AF), the most common cardiac arrhythmia encountered in clinical practice, AF…”
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Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation
Published in Circulation. Arrhythmia and electrophysiology (01-03-2020)“…Ablation is a widely used therapy for atrial fibrillation (AF); however, arrhythmia recurrence and repeat procedures are common. Studies examining surrogate…”
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A Mechanistic Clinical Trial Using ( R )- Versus (S )-Propafenone to Test RyR2 (Ryanodine Receptor) Inhibition for the Prevention of Atrial Fibrillation Induction
Published in Circulation. Arrhythmia and electrophysiology (01-10-2022)“…Experimental data suggest ryanodine receptor-mediated intracellular calcium leak is a mechanism for atrial fibrillation (AF), but evidence in humans is still…”
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Mortality Among Patients With Early-Onset Atrial Fibrillation and Rare Variants in Cardiomyopathy and Arrhythmia Genes
Published in JAMA cardiology (01-07-2022)“…Patients with early-onset atrial fibrillation (AF) are enriched for rare variants in cardiomyopathy and arrhythmia genes. The clinical significance of these…”
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Pulmonary Vein Myocardial Sleeve Length and its Association With Sex and 4q25/PITX2 Genotype
Published in JACC. Clinical electrophysiology (01-07-2023)“…Experimental evidence suggests genetic variation in 4q25/PITX2 modulates pulmonary vein (PV) myocardial sleeve length. Although PV sleeves are the main target…”
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PO-03-064 CLINICAL CHARACTERISTICS AND OUTCOMES IN PATIENTS WITH ATRIAL FIBRILLATION AND PATHOGENIC TTN VARIANTS
Published in Heart rhythm (01-05-2024)Get full text
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B-PO05-026 AGE-RELATED PREVALENCE OF RARE DISEASE-ASSOCIATED VARIANTS IN 1293 PATIENTS WITH EARLY-ONSET ATRIAL FIBRILLATION
Published in Heart rhythm (01-08-2021)Get full text
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Recurrence After Atrial Fibrillation Ablation and Investigational Biomarkers of Cardiac Remodeling
Published in Journal of the American Heart Association (19-03-2024)“…Recurrence after atrial fibrillation (AF) ablation remains common. We evaluated the association between recurrence and levels of biomarkers of cardiac…”
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PO-01-233 THE ASSOCIATION BETWEEN RECURRENCE AFTER ATRIAL FIBRILLATION ABLATION AND BIOMARKERS OF CARDIAC REMODELING
Published in Heart rhythm (01-05-2023)Get full text
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Clinical Characteristics and Outcomes in Patients With Atrial Fibrillation and Pathogenic TTN Variants
Published in JACC. Clinical electrophysiology (27-09-2024)“…TTN encodes a sarcomeric protein called titin. Pathogenic rare variants in TTN are the most common finding in patients with atrial fibrillation (AF) and…”
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Ablation for Atrial Fibrillation in Patients With Rare Pathogenic Variants in Cardiomyopathy and Arrhythmia Genes
Published in JACC. Clinical electrophysiology (20-08-2024)“…Patients with rare, pathogenic cardiomyopathy (CM) and arrhythmia variants can present with atrial fibrillation (AF). The efficacy of AF ablation in these…”
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Effects of procainamide and lidocaine on defibrillation energy requirements in patients receiving implantable cardioverter defibrillator devices
Published in Journal of cardiovascular electrophysiology (01-09-1994)“…In acute canine studies, lidocaine, but not procainamide, increases defibrillation energy requirements. We evaluated the effects of lidocaine or procainamide…”
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A randomized, double-blind, placebo-controlled, dose-ranging study of dofetilide in patients with inducible sustained ventricular tachyarrhythmias
Published in Journal of cardiovascular electrophysiology (01-09-1995)“…Dofetilide is a new antiarrhythmic agent with potent IK blocking properties in vitro. We developed a dose-ranging, placebo-controlled study design to define…”
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