Search Results - "Crawford, Diane M"

Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes by Yoneda, Zachary T, Anderson, Katherine C, Quintana, Joseph A, O'Neill, Matthew J, Sims, Richard A, Glazer, Andrew M, Shaffer, Christian M, Crawford, Diane M, Stricker, Thomas, Ye, Fei, Wells, Quinn, Stevenson, Lynne W, Michaud, Gregory F, Darbar, Dawood, Lubitz, Steven A, Ellinor, Patrick T, Roden, Dan M, Shoemaker, M Benjamin

“…Early-onset atrial fibrillation (AF) can be the initial manifestation of a more serious underlying inherited cardiomyopathy or arrhythmia syndrome. To examine…”
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2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device by O'Neill, Matthew J, Yoneda, Zachary T, Crawford, Diane M, Ye, Fei, Ao, Mingfang, Pitchford, Lisa M, Rathmacher, John A, Murray, Katherine T, Akers, Wendell S, Roden, Dan M, Michaud, Gregory F, Shoemaker, M Benjamin

“…Although catheter ablation is an effective therapy for atrial fibrillation (AF), the most common cardiac arrhythmia encountered in clinical practice, AF…”
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Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation by Shoemaker, M. Benjamin, Husser, Daniela, Roselli, Carolina, Al Jazairi, Meelad, Chrispin, Jonathan, Kühne, Michael, Neumann, Benjamin, Knight, Stacey, Sun, Han, Mohanty, Sanghamitra, Shaffer, Christian, Thériault, Sébastien, Rinke, Lauren Lee, Siland, Joylene E., Crawford, Diane M., Ueberham, Laura, Zardkoohi, Omeed, Büttner, Petra, Geelhoed, Bastiaan, Blum, Steffen, Aeschbacher, Stefanie, Smith, Jonathan D., Van Wagoner, David R., Freudling, Rebecca, Müller-Nurasyid, Martina, Montgomery, Jay, Yoneda, Zachary, Wells, Quinn, Issa, Tariq, Weeke, Peter, Jacobs, Victoria, Van Gelder, Isabelle C., Hindricks, Gerhard, Barnard, John, Calkins, Hugh, Darbar, Dawood, Michaud, Greg, Kääb, Stefan, Ellinor, Patrick, Natale, Andrea, Chung, Mina, Nazarian, Saman, Cutler, Michael J., Sinner, Moritz F., Conen, David, Rienstra, Michiel, Bollmann, Andreas, Roden, Dan M., Lubitz, Steven

“…Ablation is a widely used therapy for atrial fibrillation (AF); however, arrhythmia recurrence and repeat procedures are common. Studies examining surrogate…”
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A Mechanistic Clinical Trial Using ( R )- Versus (S )-Propafenone to Test RyR2 (Ryanodine Receptor) Inhibition for the Prevention of Atrial Fibrillation Induction by Shoemaker, M. Benjamin, Yoneda, Zachary T., Crawford, Diane M., Akers, Wendell S., Richardson, Travis, Montgomery, Jay A., Phillips, Sharon, Shyr, Yu, Saavedra, Pablo, Estrada, Juan C., Kanagasundram, Arvindh, Shen, Sharon T., Michaud, Gregory F., Crossley, George, Ellis, Christopher R., Knollmann, Bjorn C.

“…Experimental data suggest ryanodine receptor-mediated intracellular calcium leak is a mechanism for atrial fibrillation (AF), but evidence in humans is still…”
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Mortality Among Patients With Early-Onset Atrial Fibrillation and Rare Variants in Cardiomyopathy and Arrhythmia Genes by Yoneda, Zachary T, Anderson, Katherine C, Ye, Fei, Quintana, Joseph A, O'Neill, Matthew J, Sims, Richard A, Sun, Lili, Glazer, Andrew M, Davogustto, Giovanni, El-Harasis, Majd, Laws, James L, Saldivar, Brittany N, Crawford, Diane M, Stricker, Thomas, Wells, Quinn, Darbar, Dawood, Michaud, Gregory F, Stevenson, Lynne W, Lubitz, Steven A, Ellinor, Patrick T, Roden, Dan M, Shoemaker, M Benjamin

“…Patients with early-onset atrial fibrillation (AF) are enriched for rare variants in cardiomyopathy and arrhythmia genes. The clinical significance of these…”
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Pulmonary Vein Myocardial Sleeve Length and its Association With Sex and 4q25/PITX2 Genotype by El-Harasis, Majd A., Yoneda, Zachary T., Davogustto, Giovanni E., Crawford, Diane M., Laws, James L., Frye, Bradley, Herrmann, Tarrah, Patel, Bindiya, Touchton, Steven A., Roden, Dan M., Richardson, Travis D., Saavedra, Pablo, Shen, Sharon T., Estrada, Juan C., Kanagasundram, Arvindh N., Montgomery, Jay A., Michaud, Gregory F., Crossley, George H., Ellis, Christopher R., Shoemaker, M. Benjamin

“…Experimental evidence suggests genetic variation in 4q25/PITX2 modulates pulmonary vein (PV) myocardial sleeve length. Although PV sleeves are the main target…”
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A Mechanistic Clinical Trial Using (R)- Versus (S)-Propafenone to Test RyR2 (Ryanodine Receptor) Inhibition for the Prevention of Atrial Fibrillation Induction by Shoemaker, M. Benjamin, Yoneda, Zachary T., Crawford, Diane M., Akers, Wendell S., Richardson, Travis, Montgomery, Jay A., Phillips, Sharon, Shyr, Yu, Saavedra, Pablo, Estrada, Juan C., Kanagasundram, Arvindh, Shen, Sharon T., Michaud, Greg, Crossley, George, Ellis, Christopher R., Knollmann, Bjorn C.

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PO-03-064 CLINICAL CHARACTERISTICS AND OUTCOMES IN PATIENTS WITH ATRIAL FIBRILLATION AND PATHOGENIC TTN VARIANTS by Virk, Zain, El-Harasis, Majd, Yoneda, Zachary, Anderson, Katherine, Sun, Lili, Quintana, Joseph, Murphy, Brittany S., Laws, James L., Davogustto, Giovanni, O'Neill, Matthew, Varghese, Bibin, Crawford, Diane M., Williams, Hollie L., Shabani, Mahsima, Pelphrey, Cassady, Grauherr, Dakota D., Tomasek, Kelsey, Su, Yan Ru, Lancaster, Megan, Wells, Quinn S., Saavedra, Pablo J., Estrada, Juan C., Richardson, Travis D., Shen, Sharon, Kanagasundram, Arvindh N., Montgomery, Jay A., Ellis, Christopher R., Crossley, George H., Tandri, Harikrishna, Kannankeril, Prince J., Lubitz, Steven A., Stevenson, William G., Ye, Fei, Ellinor, Patrick T., Stevenson, Lynne W., Roden, Dan M., Shoemaker, M. Benjamin

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B-PO05-026 AGE-RELATED PREVALENCE OF RARE DISEASE-ASSOCIATED VARIANTS IN 1293 PATIENTS WITH EARLY-ONSET ATRIAL FIBRILLATION by Yoneda, Zachary, Anderson, Katherine C., Quintana, Joseph A., O'Neill, Matthew J., Glazer, Andrew M., Shaffer, Christian M., Crawford, Diane M., Stricker, Thomas, Wells, Quinn, Stevenson, Lynne W., Michaud, Gregory F., Darbar, Dawood, Lubitz, Steven A., Ellinor, Patrick T., Roden, Dan M., Shoemaker, Moore B.

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Recurrence After Atrial Fibrillation Ablation and Investigational Biomarkers of Cardiac Remodeling by El-Harasis, Majd A, Quintana, Joseph A, Martinez-Parachini, J Roberto, Jackson, Gregory G, Varghese, Bibin T, Yoneda, Zachary T, Murphy, Brittany S, Crawford, Diane M, Tomasek, Kelsey, Su, Yan Ru, Wells, Quinn S, Roden, Dan M, Michaud, Gregory F, Saavedra, Pablo, Estrada, Juan Carlos, Richardson, Travis D, Kanagasundram, Arvindh N, Shen, Sharon T, Montgomery, Jay A, Ellis, Christopher R, Crossley, George H, Eberl, Magdalena, Gillet, Ludovic, Ziegler, Andre, Shoemaker, M Benjamin

“…Recurrence after atrial fibrillation (AF) ablation remains common. We evaluated the association between recurrence and levels of biomarkers of cardiac…”
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PO-01-233 THE ASSOCIATION BETWEEN RECURRENCE AFTER ATRIAL FIBRILLATION ABLATION AND BIOMARKERS OF CARDIAC REMODELING by El-Harasis, Majd, Quintana, Joseph, Martinez-Parachini, Jose, Jackson, Gregory, Varghese, Bibin, Eberl, Magdalena, Gillet, Ludovic, Crawford, Diane M., Shoemaker, Ben B.

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Clinical Characteristics and Outcomes in Patients With Atrial Fibrillation and Pathogenic TTN Variants by Virk, Zain M., El-Harasis, Majd A., Yoneda, Zachary T., Anderson, Katherine C., Sun, Lili, Quintana, Joseph A., Murphy, Brittany S., Laws, James L., Davogustto, Giovanni E., O’Neill, Matthew J., Varghese, Bibin T., Crawford, Diane M., Williams, Hollie L., Shabani, Mahsima, Pelphrey, Cassady J., Grauherr, Dakota D., Tomasek, Kelsey, Su, Yan Ru, Lancaster, Megan C., Wells, Quinn S., Dendy, Jeffrey M., Saavedra, Pablo, Estrada, Juan C., Richardson, Travis D., Shen, Sharon T., Kanagasundram, Arvindh N., Montgomery, Jay A., Ellis, Christopher R., Crossley, George H., Tandri, Harikrishna, Kannankeril, Prince J., Lubitz, Steven A., Stevenson, William G., Ye, Fei, Ellinor, Patrick T., Stevenson, Lynne W., Roden, Dan M., Shoemaker, M. Benjamin

“…TTN encodes a sarcomeric protein called titin. Pathogenic rare variants in TTN are the most common finding in patients with atrial fibrillation (AF) and…”
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Ablation for Atrial Fibrillation in Patients With Rare Pathogenic Variants in Cardiomyopathy and Arrhythmia Genes by El-Harasis, Majd A., Yoneda, Zachary T., Anderson, Katherine C., Ye, Fei, Quintana, Joseph A., Martinez-Parachini, J. Roberto, Jackson, Gregory G., Varghese, Bibin T., Crawford, Diane M., Sun, Lili, Williams, Hollie L., O’Neill, Matthew J., Davogustto, Giovanni E., Laws, James L., Murphy, Brittany S., Tomasek, Kelsey, Su, Yan Ru, McQuillen, Emily, Metz, Emma, Smith, Carly, Stubbs, Doug, Grauherr, Dakota D., Wells, Quinn S., Michaud, Gregory F., Saavedra, Pablo, Carlos Estrada, Juan, Richardson, Travis D., Shen, Sharon T., Kanagasundram, Arvindh N., Montgomery, Jay A., Tandri, Harikrishna, Ellis, Christopher R., Crossley, George H., Kannankeril, Prince J., Stevenson, Lynne W., Stevenson, William G., Lubitz, Steven A., Ellinor, Patrick T., Roden, Dan M., Shoemaker, M. Benjamin

“…Patients with rare, pathogenic cardiomyopathy (CM) and arrhythmia variants can present with atrial fibrillation (AF). The efficacy of AF ablation in these…”
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Abstract A62: ATDC is required for KRAS-induced pancreatic tumorigenesis by Wang, Lidong, Yang, Huibin, Abel, Ethan V., Palmbos, Phillip L., Halbrook, Christophe, Takeuchi, Kenneth, Shi, Jiaqi, Zhang, Yaqing, Urs, Sumithra, Waghray, Meghna, Magliano, Marina Pasca di, Rhim, Andrew D., Crawford, Howard C., Simeone, Diane M.

“…Abstract We have recently demonstrated that ATDC, a novel oncogenic protein, serves as an invasive switch in pancreatic cancer (PDA) by activation of…”
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Effects of procainamide and lidocaine on defibrillation energy requirements in patients receiving implantable cardioverter defibrillator devices by Echt, D S, Gremillion, S T, Lee, J T, Roden, D M, Murray, K T, Borganelli, M, Crawford, D M, Stewart, J R, Hammon, J W

“…In acute canine studies, lidocaine, but not procainamide, increases defibrillation energy requirements. We evaluated the effects of lidocaine or procainamide…”
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A randomized, double-blind, placebo-controlled, dose-ranging study of dofetilide in patients with inducible sustained ventricular tachyarrhythmias by Echt, D S, Lee, J T, Murray, K T, Vorperian, V, Borganelli, S M, Crawford, D M, Friedrich, T, Roden, D M

“…Dofetilide is a new antiarrhythmic agent with potent IK blocking properties in vitro. We developed a dose-ranging, placebo-controlled study design to define…”
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