Search Results - "Crawford, Deborah E"

Extrusion - back to the future: Using an established technique to reform automated chemical synthesis by Crawford, Deborah E

“…Herein, the benefits which extrusion can provide for the automated continuous synthesis of organic compounds are highlighted. Extrusion is a well-established…”
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Feedback Kinetics in Mechanochemistry: The Importance of Cohesive States by Hutchings, Benjamin P., Crawford, Deborah E., Gao, Lei, Hu, Peijun, James, Stuart L.

“…Although mechanochemical synthesis is becoming more widely applied and even commercialised, greater basic understanding is needed if the field is to progress…”
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Solvent-free sonochemistry: Sonochemical organic synthesis in the absence of a liquid medium by Crawford, Deborah E

“…Sonochemistry, i.e., the application of mechanical energy in the form of sound waves, has recently been recognised for its similarity to mechanochemistry and…”
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Recent Developments in Mechanochemical Materials Synthesis by Extrusion by Crawford, Deborah E., Casaban, José

“…Mechanochemical synthesis, i.e., reactions conducted by grinding solid reactants together with no or minimal solvent, has been demonstrated as an excellent…”
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Greener Dye Synthesis: Continuous, Solvent‐Free Synthesis of Commodity Perylene Diimides by Twin‐Screw Extrusion by Cao, Qun, Crawford, Deborah E., Shi, Chengcheng, James, Stuart L.

“…A continuous, scalable, and solvent‐free method for the synthesis of various naphthalic imides and perylene diimides (PDIs) using twin‐screw extrusion (TSE) is…”
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Using Porous Liquids to Perform Liquid‐Liquid Separations by Lai, Beibei, Crawford, Deborah E., Wu, Haochen, James, Stuart L.

“…Porous liquids (PLs) are a new type of fluid sorbent investigated mainly for the separation of gas mixtures. Here, we explore their application to the…”
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Mechanochemistry Can Reduce Life Cycle Environmental Impacts of Manufacturing Active Pharmaceutical Ingredients by Galant, Or, Cerfeda, Giacomo, McCalmont, Aaron S, James, Stuart L, Porcheddu, Andrea, Delogu, Francesco, Crawford, Deborah E, Colacino, Evelina, Spatari, Sabrina

“…The scale-up of mechanochemical methods could play a transformative role in making manufacturing processes in the pharmaceutical industry greener by…”
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Solvent-Free, Continuous Synthesis of Hydrazone-Based Active Pharmaceutical Ingredients by Twin-Screw Extrusion by Crawford, Deborah E, Porcheddu, Andrea, McCalmont, Aaron S, Delogu, Francesco, James, Stuart L, Colacino, Evelina

“…Twin-screw extrusion (TSE) was used to synthesize hydantoin-based active pharmaceutical ingredients (APIs) such as nitrofurantoin and dantrolene, employing…”
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Feedback Kinetics in Mechanochemistry: The Importance of Cohesive States by Hutchings, Benjamin P., Crawford, Deborah E., Gao, Lei, Hu, Peijun, James, Stuart L.

“…Although mechanochemical synthesis is becoming more widely applied and even commercialised, greater basic understanding is needed if the field is to progress…”
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European Research in Focus: Mechanochemistry for Sustainable Industry (COST Action MechSustInd) by Hernández, José G., Halasz, Ivan, Crawford, Deborah E., Krupicka, Martin, Baláž, Matej, André, Vânia, Vella‐Zarb, Liana, Niidu, Allan, García, Felipe, Maini, Lucia, Colacino, Evelina

“…In this Guest Editorial the recently funded COST Action: CA18112 – Mechanochemistry for Sustainable Industry (MechSustInd) is introduced to the scientific…”
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Using Porous Liquids to Perform Liquid‐Liquid Separations by Lai, Beibei, Crawford, Deborah E., Wu, Haochen, James, Stuart L.

“…Porous liquids (PLs) are a new type of fluid sorbent investigated mainly for the separation of gas mixtures. Here, we explore their application to the…”
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Continuous and scalable synthesis of a porous organic cage by twin screw extrusion (TSE) by Egleston, Benjamin D, Brand, Michael C, Greenwell, Francesca, Briggs, Michael E, James, Stuart L, Cooper, Andrew I, Crawford, Deborah E, Greenaway, Rebecca L

“…The continuous and scalable synthesis of a porous organic cage ( CC3 ), obtained through a 10-component imine polycondensation between triformylbenzene and a…”
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Use of Batch Mixing To Investigate the Continuous Solvent-Free Mechanical Synthesis of OLED Materials by Twin-Screw Extrusion (TSE) by Crawford, Deborah E, James, Stuart L, McNally, Tony

“…Mechanochemical synthesis has the potential to change the way in which chemistry is conducted, particularly with regard to removing or dramatically reducing…”
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Noria and its derivatives as hosts for chemically and thermally robust Type II porous liquids by Alexander, Francesca M, Fonrouge, Sergio F, Borioni, José L, Del Pópolo, Mario G, Horton, Peter N, Coles, Simon J, Hutchings, Benjamin P, Crawford, Deborah E, James, Stuart L

“…Porous Liquids (PLs) are a new class of material that possess both fluidity and permanent porosity. As such they can act as enhanced, selective solvents and…”
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Liquids with High Compressibility by Lai, Beibei, Liu, Siyuan, Cahir, John, Sun, Yueting, Yin, Haixia, Youngs, Tristan, Tan, Jin‐Chong, Fonrouge, Sergio F., Pópolo, Mario G. Del, Borioni, José L., Crawford, Deborah E., Alexander, Francesca M., Li, Chunchun, Bell, Steven E. J., Murrer, Barry, James, Stuart L.

“…Compressibility is a fundamental property of all materials. For fluids, that is, gases and liquids, compressibility forms the basis of technologies such as…”
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Insights into mechanochemical reactions at the molecular level: simulated indentations of aspirin and meloxicam crystals by Ferguson, Michael, Moyano, M Silvina, Tribello, Gareth A, Crawford, Deborah E, Bringa, Eduardo M, James, Stuart L, Kohanoff, Jorge, Del Pópolo, Mario G

“…Although solvent-free mechanochemical synthesis continues to gain ever greater importance, the molecular scale processes that occur during such reactions…”
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Cytotoxicity of Mechanochemically Prepared Cu(II) Complexes by McCalmont, Aaron S, Ruiz, Amalia, Lagunas, M. Cristina, Al-Jamal, Wafa T, Crawford, Deborah E

“…Despite evidence that mechanochemistry has the potential to be a revolutionary manufacturing technique, the Pharma industry is still reluctant to introduce…”
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Greener Dye Synthesis: Continuous, Solvent‐Free Synthesis of Commodity Perylene Diimides by Twin‐Screw Extrusion by Cao, Qun, Crawford, Deborah E., Shi, Chengcheng, James, Stuart L.

“…A continuous, scalable, and solvent‐free method for the synthesis of various naphthalic imides and perylene diimides (PDIs) using twin‐screw extrusion (TSE) is…”
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Continuous and scalable synthesis of a porous organic cage by twin screw extrusion (TSE)† †Electronic supplementary information (ESI) available: full experimental and characterisation details. See DOI: 10.1039/d0sc01858a by Egleston, Benjamin D., Brand, Michael C., Greenwell, Francesca, Briggs, Michael E., James, Stuart L., Cooper, Andrew I., Crawford, Deborah E., Greenaway, Rebecca L.

“…Twin screw extrusion (TSE) is demonstrated as an alternative synthetic method for preparing a prolific porous organic cage. The continuous and scalable…”
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Making 2‐D Materials Mechanochemically by Twin‐Screw Extrusion: Continuous Exfoliation of Graphite to Multi‐Layered Graphene by Chen, Haili, Cao, Qun, Ye, Ziwei, Lai, Beibei, Zhang, Yuancheng, Dong, He, Crawford, Deborah E., Istrate, Oana M., James, Stuart L.

“…Mechanochemistry has developed rapidly in recent years for efficient chemicals and materials synthesis. Twin screw extrusion (TSE) is a particularly promising…”
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