Search Results - "Crawford, D."

A human coronavirus evolves antigenically to escape antibody immunity by Eguia, Rachel T, Crawford, Katharine H D, Stevens-Ayers, Terry, Kelnhofer-Millevolte, Laurel, Greninger, Alexander L, Englund, Janet A, Boeckh, Michael J, Bloom, Jesse D

“…There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how…”
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Characterising the castration-resistant prostate cancer population: a systematic review by Kirby, M, Hirst, C, Crawford, E D

“…Castration-resistant prostate cancer (CRPC) is an advanced form of prostate cancer associated with poor survival rates. However, characterisation of the…”
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Viable bacterial colonization is highly limited in the human intestine in utero by Rackaityte, E., Halkias, J., Fukui, E. M., Mendoza, V. F., Hayzelden, C., Crawford, E. D., Fujimura, K. E., Burt, T. D., Lynch, S. V.

“…Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet whether viable microbes exist in utero and interact with the intestinal…”
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Caspase Substrates and Cellular Remodeling by Crawford, Emily D, Wells, James A

“…The caspases are unique proteases that mediate the major morphological changes of apoptosis and various other cellular remodeling processes. As we catalog and…”
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Depletion of Abundant Sequences by Hybridization (DASH): using Cas9 to remove unwanted high-abundance species in sequencing libraries and molecular counting applications by Gu, W, Crawford, E D, O'Donovan, B D, Wilson, M R, Chow, E D, Retallack, H, DeRisi, J L

“…Next-generation sequencing has generated a need for a broadly applicable method to remove unwanted high-abundance species prior to sequencing. We introduce…”
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Does the Summer Arctic Frontal Zone Influence Arctic Ocean Cyclone Activity? by Crawford, Alex D., Serreze, Mark C.

“…Extratropical cyclone activity over the central Arctic Ocean reaches its peak in summer. Previous research has argued for the existence of two external source…”
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Current and Future Uses of Aluminum in the Automotive Industry by Long, R. S., Boettcher, E., Crawford, D.

“…Aluminum use is growing in automotive closures and body in white applications to improve vehicle performance and fuel economy. The auto industry is looking for…”
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Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Crawford, Katharine H D, Dingens, Adam S, Eguia, Rachel, Wolf, Caitlin R, Wilcox, Naomi, Logue, Jennifer K, Shuey, Kiel, Casto, Amanda M, Fiala, Brooke, Wrenn, Samuel, Pettie, Deleah, King, Neil P, Greninger, Alexander L, Chu, Helen Y, Bloom, Jesse D

“…Abstract Most individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop neutralizing antibodies that target the viral…”
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Selective Catalytic Reduction of N2 to N2H4 by a Simple Fe Complex by Hill, Peter J, Doyle, Laurence R, Crawford, Andrew D, Myers, William K, Ashley, Andrew E

“…The catalytic fixation of N2 by molecular Fe compounds is a rapidly developing field, yet thus far few complexes can effect this transformation, and none are…”
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Evaluation of 14 organic solvents and carriers for screening applications in zebrafish embryos and larvae by Maes, Jan, Verlooy, Lien, Buenafe, Olivia E, de Witte, Peter A M, Esguerra, Camila V, Crawford, Alexander D

“…Zebrafish are rapidly growing in popularity as an in vivo model system for chemical genetics, drug discovery, and toxicology, and more recently also for…”
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Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs by Afrikanova, Tatiana, Serruys, Ann-Sophie K, Buenafe, Olivia E M, Clinckers, Ralph, Smolders, Ilse, de Witte, Peter A M, Crawford, Alexander D, Esguerra, Camila V

“…Zebrafish have recently emerged as an attractive in vivo model for epilepsy. Seven-day-old zebrafish larvae exposed to the GABA(A) antagonist pentylenetetrazol…”
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Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors by Romero, F. Anthony, Taylor, Alexander M, Crawford, Terry D, Tsui, Vickie, Côté, Alexandre, Magnuson, Steven

“…Bromodomains, small protein modules that recognize acetylated lysine on histones, play a significant role in the epigenome, where they function as “readers”…”
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Seizing the moment: Zebrafish epilepsy models by Gawel, Kinga, Langlois, Melanie, Martins, Teresa, van der Ent, Wietske, Tiraboschi, Ettore, Jacmin, Maxime, Crawford, Alexander D., Esguerra, Camila V.

“…•Zebrafish is gaining recognition as a valuable model organism in epilepsy research•Zebrafish models allow for rapid identification of new drug leads•Genetic…”
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Using timing of ice retreat to predict timing of fall freeze‐up in the Arctic by Stroeve, Julienne C., Crawford, Alex D., Stammerjohn, Sharon

“…Reliable forecasts of the timing of sea ice advance are needed in order to reduce risks associated with operating in the Arctic as well as planning of human…”
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cognac: rapid generation of concatenated gene alignments for phylogenetic inference from large, bacterial whole genome sequencing datasets by Crawford, Ryan D, Snitkin, Evan S

“…The quantity of genomic data is expanding at an increasing rate. Tools for phylogenetic analysis which scale to the quantity of available data are required. To…”
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Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays by Crawford, Katharine H D, Eguia, Rachel, Dingens, Adam S, Loes, Andrea N, Malone, Keara D, Wolf, Caitlin R, Chu, Helen Y, Tortorici, M Alejandra, Veesler, David, Murphy, Michael, Pettie, Deleah, King, Neil P, Balazs, Alejandro B, Bloom, Jesse D

“…SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing antibodies. Therefore, assays to measure how antibodies and sera…”
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pathway-based classification of human breast cancer by Gatza, Michael L, Lucas, Joseph E, Barry, William T, Kim, Jong Wook, Wang, Quanli, Crawford, Matthew D, Datto, Michael B, Kelley, Michael, Mathey-Prevot, Bernard, Potti, Anil, Nevins, Joseph R

“…The hallmark of human cancer is heterogeneity, reflecting the complexity and variability of the vast array of somatic mutations acquired during oncogenesis. An…”
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Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi by Brillatz, Théo, Lauritano, Chiara, Jacmin, Maxime, Khamma, Supitcha, Marcourt, Laurence, Righi, Davide, Romano, Giovanna, Esposito, Francesco, Ianora, Adrianna, Queiroz, Emerson F, Wolfender, Jean-Luc, Crawford, Alexander D

“…With the goal of identifying neuroactive secondary metabolites from microalgae, a microscale in vivo zebrafish bioassay for antiseizure activity was used to…”
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Family food environment and dietary behaviors likely to promote fatness in 5-6 year-old children by Campbell, K.J, Crawford, D.A, Ball, K

“…Background: The family food environment (FFE) is likely to exert important influences on young children's eating. Examination of multiple aspects of the FFE…”
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Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine by Zhang, Yifan, Kecskés, Angéla, Copmans, Daniëlle, Langlois, Mélanie, Crawford, Alexander D, Ceulemans, Berten, Lagae, Lieven, de Witte, Peter A M, Esguerra, Camila V

“…Dravet syndrome (DS) is one of the most pharmacoresistant and devastating forms of childhood epilepsy syndromes. Distinct de novo mutations in the SCN1A gene…”
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