Search Results - "Craven, Rebecca C."

The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B by Carmichael, Jillian C, Yokota, Hiroki, Craven, Rebecca C, Schmitt, Anthony, Wills, John W

“…All herpesviruses have mechanisms for passing through cell junctions, which exclude neutralizing antibodies and offer a clear path to neighboring, uninfected…”
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A Two-Pronged Structural Analysis of Retroviral Maturation Indicates that Core Formation Proceeds by a Disassembly-Reassembly Pathway Rather than a Displacive Transition by Keller, Paul W, Huang, Rick K, England, Matthew R, Waki, Kayoko, Cheng, Naiqian, Heymann, J Bernard, Craven, Rebecca C, Freed, Eric O, Steven, Alasdair C

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Atomic Modeling of an Immature Retroviral Lattice Using Molecular Dynamics and Mutagenesis by Goh, Boon Chong, Perilla, Juan R., England, Matthew R., Heyrana, Katrina J., Craven, Rebecca C., Schulten, Klaus

“…Defining the molecular interaction between Gag proteins in an assembled hexagonal lattice of immature retrovirus particles is crucial for elucidating…”
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The Small RING Finger Protein Z Drives Arenavirus Budding: Implications for Antiviral Strategies by Perez, Mar, Craven, Rebecca C., de la Torre, Juan C.

“…By using a reverse genetics system that is based on the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV), we have identified the arenavirus…”
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Structural Model of the Tubular Assembly of the Rous Sarcoma Virus Capsid Protein by Jeon, Jaekyun, Qiao, Xin, Hung, Ivan, Mitra, Alok K, Desfosses, Ambroise, Huang, Daniel, Gor’kov, Peter L, Craven, Rebecca C, Kingston, Richard L, Gan, Zhehong, Zhu, Fangqiang, Chen, Bo

“…The orthoretroviral capsid protein (CA) assembles into polymorphic capsids, whose architecture, assembly, and stability are still being investigated. The…”
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Critical Role of Conserved Hydrophobic Residues within the Major Homology Region in Mature Retroviral Capsid Assembly by PURDY, John G, FLANAGAN, John M, ROPSON, Ira J, RENNOLL-BANKERT, Kristen E, CRAVEN, Rebecca C

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Overlapping Roles of the Rous Sarcoma Virus Gag p10 Domain in Nuclear Export and Virion Core Morphology by Scheifele, Lisa Z, Kenney, Scott P, Cairns, Tina M, Craven, Rebecca C, Parent, Leslie J

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Suppression of a Morphogenic Mutant in Rous Sarcoma Virus Capsid Protein by a Second-Site Mutation: a Cryoelectron Tomography Study by Butan, Carmen, Lokhandwala, Parvez M, Purdy, John G, Cardone, Giovanni, Craven, Rebecca C, Steven, Alasdair C

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Visualization of a missing link in retrovirus capsid assembly by Cardone, Giovanni, Craven, Rebecca C, Purdy, John G, Steven, Alasdair C, Cheng, Naiqian

“…For a retrovirus such as HIV to be infectious, a properly formed capsid is needed; however, unusually among viruses, retrovirus capsids are highly variable in…”
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Lysines Close to the Rous Sarcoma Virus Late Domain Critical for Budding by SPIDEL, Jared L, CRAVEN, Rebecca C, WILSON, Carol B, PATNAIK, Akash, HUATING WANG, MANSKY, Louis M, WILLS, John W

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Genetic Studies of the β-Hairpin Loop of Rous Sarcoma Virus Capsid Protein by SPIDEL, Jared L, WILSON, Carol B, CRAVEN, Rebecca C, WILLS, John W

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Contributions of Charged Residues in Structurally Dynamic Capsid Surface Loops to Rous Sarcoma Virus Assembly by Heyrana, Katrina J, Goh, Boon Chong, Perilla, Juan R, Nguyen, Tam-Linh N, England, Matthew R, Bewley, Maria C, Schulten, Klaus, Craven, Rebecca C

“…Extensive studies of orthoretroviral capsids have shown that many regions of the CA protein play unique roles at different points in the virus life cycle. The…”
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RSV Capsid Polymorphism Correlates with Polymerization Efficiency and Envelope Glycoprotein Content: Implications that Nucleation Controls Morphogenesis by Butan, Carmen, Winkler, Dennis C., Heymann, J. Bernard, Craven, Rebecca C., Steven, Alasdair C.

“…We used cryo-electron tomography to visualize Rous sarcoma virus, the prototypic alpharetrovirus. Its polyprotein Gag assembles into spherical procapsids,…”
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Potential role for CA-SP in nucleating retroviral capsid maturation by England, Matthew R, Purdy, John G, Ropson, Ira J, Dalessio, Paula M, Craven, Rebecca C

“…During virion maturation, the Rous sarcoma virus (RSV) capsid protein is cleaved from the Gag protein as the proteolytic intermediate CA-SP. Further trimming…”
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Lethal mutations in the major homology region and their suppressors act by modulating the dimerization of the rous sarcoma virus capsid protein C-terminal domain by Dalessio, Paula M., Craven, Rebecca C., Lokhandwala, Parvez M., Ropson, Ira J.

“…An infective retrovirus requires a mature capsid shell around the viral replication complex. This shell is formed by about 1500 capsid protein monomers,…”
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Retroviral Capsid Assembly: A Role for the CA Dimer in Initiation by Purdy, John G., Flanagan, John M., Ropson, Ira J., Craven, Rebecca C.

“…In maturing retroviral virions, CA protein assembles to form a capsid shell that is essential for infectivity. The structure of the two folded domains…”
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Cooperative role of the MHR and the CA dimerization helix in the maturation of the functional retrovirus capsid by Lokhandwala, Parvez M, Nguyen, Tam-Linh N, Bowzard, J. Bradford, Craven, Rebecca C

“…Abstract The second helix in the C-terminal domain of retroviral capsid (CA) protein functions as the site of dimerization between subunits in capsid assembly…”
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Late Domain Function Identified in the Vesicular Stomatitis Virus M Protein by Use of Rhabdovirus-Retrovirus Chimeras by Craven, R C, Harty, R N, Paragas, J, Palese, P, Wills, J W

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Form, function, and use of retroviral gag proteins by Wills, J W, Craven, R C

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Second-Site Suppressors of Rous Sarcoma Virus CA Mutations: Evidence for Interdomain Interactions by Bowzard, J B, Wills, J W, Craven, R C

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