Search Results - "Cranmer, L"

An effective vaccine is only the first step: the need to create and sustain demand for TB vaccines by Nelson, K. N., Shah, N. S., Cranmer, L. M., Vasudevan, L., Bednarczyk, R. A.

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Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy by Dinoso, J.B, Kim, S.Y, Wiegand, A.M, Palmer, S.E, Gange, S.J, Cranmer, L, O'Shea, A, Callender, M, Spivak, A, Brennan, T, Kearney, M.F, Proschan, M.A, Mican, J.M, Rehm, C.A, Coffin, J.M, Mellors, J.W, Siliciano, R.F, Maldarelli, F

“…In HIV-1-infected individuals on currently recommended antiretroviral therapy (ART), viremia is reduced to <50 copies of HIV-1 RNA per milliliter, but…”
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The effect of antenatal isoniazid preventive therapy on birth outcomes in Western Kenya by Quincer, E. M., Lyland, A., Onyango, D., LaCourse, S. M., Figueroa, J., John-Stewart, G. C., Cranmer, L. M.

“…BACKGROUND: Pregnant women living with HIV (WLHIV) are at high risk for TB. There are limited data to inform whether TB preventive therapy is safe in…”
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16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria by Watts, G.S., Youens‐Clark, K., Slepian, M.J., Wolk, D.M., Oshiro, M.M., Metzger, G.S., Dhingra, D., Cranmer, L.D., Hurwitz, B.L.

“…Aims Test the choice of 16S rRNA gene amplicon and data analysis method on the accuracy of identification of clinically important bacteria utilizing a benchtop…”
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14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function by Schoenwaelder, Simone M., Darbousset, Roxane, Cranmer, Susan L., Ramshaw, Hayley S., Orive, Stephanie L., Sturgeon, Sharelle, Yuan, Yuping, Yao, Yu, Krycer, James R., Woodcock, Joanna, Maclean, Jessica, Pitson, Stuart, Zheng, Zhaohua, Henstridge, Darren C., van der Wal, Dianne, Gardiner, Elizabeth E., Berndt, Michael C., Andrews, Robert K., James, David E., Lopez, Angel F., Jackson, Shaun P.

“…The 14-3-3 family of adaptor proteins regulate diverse cellular functions including cell proliferation, metabolism, adhesion and apoptosis. Platelets express…”
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Neoadjuvant Chemoradiation With Ifosfamide and Etoposide in the Management of Soft Tissue Sarcomas: A Single-Institution Review by Morrison, C, Hayman, J, Davuluri, R, Cranmer, L, Howell, K.J

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Incidence and correlates of tuberculosis IGRA conversion among HIV-infected postpartum women by Jonnalagadda, S., LaCourse, S. M., Otieno, P., Lohman-Payne, B., Maleche-Obimbo, E., Cranmer, L. M., John-Stewart, G. C.

“…SETTING: Prevention of maternal-to-child transmission program at a tertiary care hospital in Nairobi, Kenya. The risk of acquiring Mycobacterium tuberculosis…”
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Tuberculosis interferon-gamma responses in the breast milk of human immunodeficiency virus infected mothers by Cranmer, L. M., Kanyugo, M., Lohman-Payne, B., Tapia, K., John-Stewart, G. C.

“…Tuberculosis (TB) cellular immune responses were examined in the breast milk of human immunodeficiency virus infected mothers using the T-SPOT®. TB…”
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Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket by Frazzetto, Mark, Suphioglu, Cenk, Zhu, Jiuxiang, Schmidt-Kittler, Oleg, Jennings, Ian G, Cranmer, Susan L, Jackson, Shaun P, Kinzler, Kenneth W, Vogelstein, Bert, Thompson, Philip E

“…The last few years have seen the identification of numerous small molecules that selectively inhibit specific class I isoforms of PI3K (phosphoinositide…”
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Integrating tuberculosis screening in Kenyan Prevention of Mother-To-Child Transmission programs by Cranmer, L. M., Langat, A., Ronen, K., McGrath, C. J., LaCourse, S., Pintye, J., Odeny, B., Singa, B., Katana, A., Nganga, L., Kinuthia, J., John-Stewart, G.

“…BACKGROUND: Tuberculosis (TB) screening in Prevention of Mother-To-Child Transmission (PMTCT) programs is important to improve TB detection, prevention and…”
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Intracranial Solitary Fibrous Tumor/Hemangiopericytoma Treated with Microsurgical Resection: Retrospective Cohort Analysis of a Single-Center Experience by Swaminathan, Shreya, Ruzevick, Jacob, Venur, Vyshak, Halasz, Lia M, Rockhill, Jason, Gonzalez-Cuyar, Luis, Cranmer, Lee D, Ferreira, Manuel, Jr

“…Objective: To provide benchmarks for further studies of solitary fibrous tumor/hemangiopericytoma (SFT/HPC) of the central nervous system (CNS), we…”
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A Review of Recent Decision-Analytic Models Used to Evaluate the Economic Value of Cancer Treatments by Bullement, Ash, Cranmer, Holly L., Shields, Gemma E.

“…Cost-effectiveness analysis provides information on the potential value of new cancer treatments, which is particularly pertinent for decision makers as demand…”
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GPIbα-filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis by Ellis, Marc L, Terreaux, Antoine, Alwis, Imala, Smythe, Rhyll, Perdomo, Jose, Eckly, Anita, Cranmer, Susan L, Passam, Freda H, Maclean, Jessica, Schoenwaelder, Simone M, Ruggeri, Zaverio M, Lanza, Francois, Taoudi, Samir, Yuan, Yuping, Jackson, Shaun P

“…Glycoprotein Ibα (GPIbα) is expressed on the surface of platelets and megakaryocytes (MKs) and anchored to the membrane skeleton by filamin A (flnA). Although…”
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An Investigation into the Relationship Between Choice of Model Structure and How to Adjust for Subsequent Therapies Using a Case Study in Oncology by Cranmer, Holly L., Shields, Gemma E., Bullement, Ash

“…Background A common challenge in health technology assessments (HTAs) of cancer treatments is how subsequent therapy use within the trial follow-up may…”
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The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells by Yuan, Y, Kulkarni, S, Ulsemer, P, Cranmer, S L, Yap, C L, Nesbitt, W S, Harper, I, Mistry, N, Dopheide, S M, Hughan, S C, Williamson, D, de la Salle, C, Salem, H H, Lanza, F, Jackson, S P

“…Platelet adhesion to sites of vascular injury is initiated by the binding of the platelet glycoprotein (GP) Ib-V-IX complex to matrix-bound von Willebrand…”
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Correction: Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function by Schoenwaelder, Simone M., Darbousset, Roxane, Cranmer, Susan L., Ramshaw, Hayley S., Orive, Stephanie L., Sturgeon, Sharelle, Yuan, Yuping, Yao, Yu, Krycer, James R., Woodcock, Joanna, Maclean, Jessica, Pitson, Stuart, Zheng, Zhaohua, Henstridge, Darren C., van der Wal, Dianne, Gardiner, Elizabeth E., Berndt, Michael C., Andrews, Robert K., James, David E., Lopez, Angel F., Jackson, Shaun P.

“…Nature Communications 7: Article number: 12862 (2016); Published: 27 September 2016; Updated: 30 August 2017 In Supplementary Fig. 7 of this Article, graphs…”
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An alternative to serum for cultivation of Plasmodium falciparum in vitro by Cranmer, Susan L., Magowan, Cathleen, Liang, Joy, Coppel, Ross L., Cooke, Brian M.

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Identification of a novel 14-3-3ζ binding site within the cytoplasmic tail of platelet glycoprotein Ibα by Mangin, Pierre, David, Tovo, Lavaud, Vincent, Cranmer, Susan L., Pikovski, Inna, Jackson, Shaun P., Berndt, Michael C., Cazenave, Jean-Pierre, Gachet, Christian, Lanza, François

“…The glycoprotein Ib-V-IX (GPIb-V-IX) complex interacts with subendothelial von Willebrand factor (VWF) to ensure recruitment of platelets at sites of vascular…”
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Cytoskeletal regulation of the platelet glycoprotein Ib/V/IX–von Willebrand factor interaction by Mistry, Nayna, Cranmer, Susan L., Yuan, Yuping, Mangin, Pierre, Dopheide, Sacha M., Harper, Ian, Giuliano, Simon, Dunstan, Dave E., Lanza, Francois, Salem, Hatem H., Jackson, Shaun P.

“…Shear-induced binding of von Willebrand factor (vWf) to the platelet glycoprotein (GP) Ib/V/IX complex plays a key role in initiating platelet adhesion and…”
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Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex by Perrault, Christelle, Mangin, Pierre, Santer, Martine, Baas, Marie-Jeanne, Moog, Sylvie, Cranmer, Susan L., Pikovski, Inna, Williamson, David, Jackson, Shaun P., Cazenave, Jean-Pierre, Lanza, François

“…Glycoprotein (GP) Ib/V/IX complex–dependent platelet adhesion to von Willebrand factor (VWF) is supported by the 45-kd N-terminal extracellular domain of the…”
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