Search Results - "Crankshaw, D J"
-
1
Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues
Published in Journal of applied toxicology (01-04-2008)“…Atrazine (ATR) is a pesticide used widely throughout North America. Although not directly estrogenic, ATR treatment has been shown to increase aromatase…”
Get full text
Journal Article -
2
Maternal body mass index and spontaneous contractility of human myometrium in pregnancy
Published in Journal of perinatology (01-05-2017)“…Objective: There is controversy as to whether maternal body mass index (BMI) influences the contractility of human myometrium in pregnancy. The aim of this…”
Get full text
Journal Article -
3
Effects of some isoprostanes on the human umbilical artery in vitro
Published in British journal of pharmacology (01-02-2000)“…Cumulative concentration‐effect curves for the selective prostanoid TP receptor agonist U46619 and six isoprostanes were constructed in the human isolated…”
Get full text
Journal Article -
4
Excitatory and inhibitory actions of isoprostanes in human and canine airway smooth muscle
Published in The Journal of pharmacology and experimental therapeutics (01-11-2000)“…Isoprostanes are generated nonenzymatically during free radical-mediated lipid peroxidation, and are used clinically and experimentally as markers of oxidative…”
Get more information
Journal Article -
5
Isoprostanes: more than just mere markers
Published in Molecular and cellular biochemistry (01-11-2003)“…Isoprostanes are members of a family of prostaglandin isomers that are produced by free radical-catalysed mechanisms. They have become well-recognized…”
Get full text
Journal Article -
6
Effects of some naturally occurring prostanoids and some cyclooxygenase inhibitors on the contractility of the human lower uterine segment in vitro
Published in Canadian journal of physiology and pharmacology (01-08-1994)“…The contractility of strips of human lower segment myometrium obtained from elective cesarean section performed at term of pregnancy was studied in vitro. The…”
Get more information
Journal Article -
7
Operational correlates of prostanoid TP receptor expression in human non‐pregnant myometrium are unaffected by excision site or menstrual cycle status of the donor
Published in British journal of pharmacology (01-12-1999)“…Cumulative concentration‐effect curves for the selective prostanoid TP receptor agonist, U46619, were constructed in strips of human non‐pregnant myometrium…”
Get full text
Journal Article -
8
Characterization of the prostanoid TP receptor population in human nonpregnant myometrium
Published in The Journal of pharmacology and experimental therapeutics (01-10-1996)“…We have used both functional and binding studies to fully characterize the prostanoid TP receptor in the myometrium from nonpregnant human donors. Both…”
Get more information
Journal Article -
9
Characterization of excitatory prostanoid receptors in the human umbilical artery in vitro
Published in British journal of pharmacology (01-12-1999)“…5‐HT and the prostanoid TP receptor agonists, U46619 and I‐BOP, constricted the human umbilical artery with pEC50 values of 7.3±0.2, 6.7±0.1, and 7.3±0.2,…”
Get full text
Journal Article -
10
Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes
Published in Journal of reproduction & fertility (01-01-1995)“…Prostanoid receptors regulating the contractility of strips of myometrium obtained from nonpregnant ewes during the breeding season were classified…”
Get full text
Journal Article -
11
Inhibitory prostanoid EP receptors in human non-pregnant myometrium
Published in European journal of pharmacology (28-07-1999)“…Prostanoid EP receptor agonists relaxed cloprostenol-stimulated contraction of human non-pregnant myometrium in vitro with pEC 50 values of ( n=4):…”
Get full text
Journal Article -
12
Pharmacological techniques for the in vitro study of the uterus
Published in Journal of pharmacological and toxicological methods (01-03-2001)Get full text
Journal Article -
13
Effects of prostanoids on the rat's myometrium in vitro during pregnancy
Published in Biology of reproduction (01-03-1992)“…The objectives of this study were to determine the effects of pregnancy in the rat on the contractile response of the myometrium in vitro to a number of…”
Get full text
Journal Article -
14
The effects of some synthetic prostanoids on the contractility of the human lower uterine segment in vitro
Published in American journal of obstetrics and gynecology (01-12-1988)“…We have investigated the ability of three synthetic prostanoids to directly influence uterine contractility by studying the effects in vitro. Strips of lower…”
Get more information
Journal Article -
15
Role of inositol phospholipid hydrolysis in the initiation of agonist-induced contractions of rat uterus: effects of domination by 17 beta-estradiol and progesterone
Published in Canadian journal of physiology and pharmacology (01-01-1988)“…The role of inositol phospholipid (IP) hydrolysis in agonist-mediated contractility was examined in rat uterine smooth muscle by comparing carbachol-,…”
Get more information
Journal Article -
16
The sensitivity of the longitudinal and circular muscle layers of the rat's myometrium to oxytocin in vitro during pregnancy
Published in Canadian journal of physiology and pharmacology (01-05-1987)“…To test the hypothesis that binding site regulation is the primary process controlling the responsiveness of the rat's myometrium to oxytocin during pregnancy,…”
Get more information
Journal Article -
17
Alpha-2 adrenoceptors on nerves and muscles of rat uterus
Published in The Journal of pharmacology and experimental therapeutics (01-03-1988)“…To test the hypothesis that functional postsynaptic alpha-2 adrenoceptors exist in rat myometrium, we examined whether specific binding sites for…”
Get more information
Journal Article -
18
The effects of prostanoids on estrogen-dominated rat myometrial longitudinal muscle in vitro
Published in Biology of reproduction (01-09-1988)“…The purpose of these experiments was to characterize the contractile response of longitudinal muscle from the estrogen-dominated rat uterus to natural and…”
Get full text
Journal Article -
19
Muscarinic cholinoceptors in the rabbit's myometrium: a study of the relationship between binding and response
Published in European journal of pharmacology (18-05-1984)“…The relationship between [3H](-)-quinuclinidyl benzilate [( 3H](-)QNB) binding and muscarinic cholinoceptors in the myometrium of the oestrogen treated rabbit…”
Get more information
Journal Article -
20
Control of intracellular Ca2+ activity in rat myometrium
Published in The American journal of physiology (01-01-1977)“…Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were…”
Get full text
Journal Article