Search Results - "Crane, John A"

Valsartan Regulates Myocardial Autophagy and Mitochondrial Turnover in Experimental Hypertension by Zhang, Xin, Li, Zi-Lun, Crane, John A, Jordan, Kyra L, Pawar, Aditya S, Textor, Stephen C, Lerman, Amir, Lerman, Lilach O

“…Renovascular hypertension alters cardiac structure and function. Autophagy is activated during left ventricular hypertrophy and linked to adverse cardiac…”
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Blood Oxygen Level–Dependent Magnetic Resonance Imaging Identifies Cortical Hypoxia in Severe Renovascular Disease by Gloviczki, Monika L, Glockner, James F, Crane, John A, McKusick, Michael A, Misra, Sanjay, Grande, Joseph P, Lerman, Lilach O, Textor, Stephen C

“…Atherosclerotic renal artery stenosis has a range of manifestations depending on the severity of vascular occlusion. The aim of this study was to examine…”
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Magnetic Resonance Elastography Noninvasively Detects In Vivo Renal Medullary Fibrosis Secondary to Swine Renal Artery Stenosis by Korsmo, Michael J, Ebrahimi, Behzad, Eirin, Alfonso, Woollard, John R, Krier, James D, Crane, John A, Warner, Lizette, Glaser, Kevin, Grimm, Roger, Ehman, Richard L, Lerman, Lilach O

“…OBJECTIVESMagnetic resonance elastography (MRE) can noninvasively sample tissue stiffness in vivo. Renal fibrosis secondary to renal artery stenosis (RAS),…”
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Transition From Obesity to Metabolic Syndrome Is Associated With Altered Myocardial Autophagy and Apoptosis by Li, Zi-Lun, Woollard, John R, Ebrahimi, Behzad, Crane, John A, Jordan, Kyra L, Lerman, Amir, Wang, Shen-Ming, Lerman, Lilach O

“…OBJECTIVE—Transition from obesity to metabolic-syndrome (MetS) promotes cardiovascular diseases, but the underlying cardiac pathophysiological mechanisms are…”
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Compartmental Analysis of Renal BOLD MRI Data: Introduction and Validation by Ebrahimi, Behzad, Gloviczki, Monika, Woollard, John R, Crane, John A, Textor, Stephen C, Lerman, Lilach O

“…OBJECTIVES:Functional blood oxygenation level–dependent (BOLD) magnetic resonance imaging is a powerful tool to assess renal function, but BOLD analysis using…”
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Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension by Eirin, Alfonso, Williams, Barbara J, Ebrahimi, Behzad, Zhang, Xin, Crane, John A, Lerman, Amir, Textor, Stephen C, Lerman, Lilach O

“…BACKGROUND:Renovascular hypertension (RVHT) increases cardiovascular morbidity and mortality. Renal revascularization with percutaneous transluminal renal…”
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Noninvasive In Vivo Assessment of Renal Tissue Elasticity During Graded Renal Ischemia Using MR Elastography by Warner, Lizette, Yin, Meng, Glaser, Kevin J, Woollard, John A, Carrascal, Carolina A, Korsmo, Michael J, Crane, John A, Ehman, Richard L, Lerman, Lilach O

“…OBJECTIVES:Magnetic resonance elastography (MRE) allows noninvasive assessment of tissue stiffness in vivo. Renal arterial stenosis (RAS), a narrowing of the…”
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Changes in Glomerular Filtration Rate After Renal Revascularization Correlate With Microvascular Hemodynamics and Inflammation in Swine Renal Artery Stenosis by Eirin, Alfonso, Ebrahimi, Behzad, Zhang, Xin, Zhu, Xiang-Yang, Tang, Hui, Crane, John A, Lerman, Amir, Textor, Stephen C, Lerman, Lilach O

“…BACKGROUND—The selection of patients with renal artery stenosis (RAS) likely to improve glomerular filtration rate (GFR) after percutaneous transluminal renal…”
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Experimental coronary artery stenosis accelerates kidney damage in renovascular hypertensive swine by Sun, Dong, Eirin, Alfonso, Zhu, Xiang-Yang, Zhang, Xin, Crane, John A, Woollard, John R, Lerman, Amir, Lerman, Lilach O

“…The impact of coronary artery stenosis (CAS) on renal injury is unknown. Here we tested whether the existence of CAS, regardless of concurrent atherosclerosis,…”
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Obesity-metabolic derangement preserves hemodynamics but promotes intrarenal adiposity and macrophage infiltration in swine renovascular disease by Zhang, Xin, Li, Zi-Lun, Woollard, John R, Eirin, Alfonso, Ebrahimi, Behzad, Crane, John A, Zhu, Xiang-Yang, Pawar, Aditya S, Krier, James D, Jordan, Kyra L, Tang, Hui, Textor, Stephen C, Lerman, Amir, Lerman, Lilach O

“…Obesity-metabolic disorders (ObM) often accompany renal artery stenosis (RAS). We hypothesized that the coexistence of ObM and RAS magnifies inflammation and…”
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Angiotensin receptor blockade has protective effects on the poststenotic porcine kidney by Zhang, Xin, Eirin, Alfonso, Li, Zi-Lun, Crane, John A, Krier, James D, Ebrahimi, Behzad, Pawar, Aditya S, Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L, Lerman, Amir, Textor, Stephen C, Lerman, Lilach O

“…Angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers (ARBs) may induce an acute decrease of glomerular filtration rate (GFR) in the…”
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Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney by Urbieta-Caceres, Victor H, Lavi, Ronit, Zhu, Xiang-Yang, Crane, John A, Textor, Stephen C, Lerman, Amir, Lerman, Lilach O

“…Atherosclerotic renal artery stenosis (ARAS) is increasingly identified in patients with end-stage renal disease. Renal function in ARAS patients deteriorates…”
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Polycystic Kidneys Have Decreased Vascular Density: A Micro-CT Study by Xu, Rende, Franchi, Federico, Miller, Brent, Crane, John A., Peterson, Karen M., Psaltis, Peter J., Harris, Peter C., Lerman, Lilach O., Rodriguez-Porcel, Martin

“…Objective Polycystic kidney disease (PKD) is a common cause of end‐stage renal failure and many of these patients suffer vascular dysfunction and hypertension…”
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Evolution of cardiac and renal impairment detected by high-field cardiovascular magnetic resonance in mice with renal artery stenosis by Ebrahimi, Behzad, Crane, John A, Knudsen, Bruce E, Macura, Slobodan I, Grande, Joseph P, Lerman, Lilach O

“…Renal artery stenosis (RAS) promotes hypertension and cardiac dysfunction. The 2-kidney, 1-clip mouse model in many ways resembles RAS in humans and is…”
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Hemodynamic Determinants of Perivascular Collateral Development in Swine Renal Artery Stenosis by Krier, James D., Crane, John A., Eirin, Alfonso, Zhu, Xiang-Yang, Lerman, Amir, Lerman, Lilach O.

“…BACKGROUND Renal artery stenosis (RAS) resulting in reduced renal blood flow (RBF) is a common cause of secondary hypertension and deterioration of renal…”
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Early experimental hypertension preserves the myocardial microvasculature but aggravates cardiac injury distal to chronic coronary artery obstruction by Urbieta Caceres, Victor Hugo, Lin, Jing, Zhu, Xiang-Yang, Favreau, Frederic D, Gibson, Matthew E, Crane, John A, Lerman, Amir, Lerman, Lilach O

“…Coronary artery disease is a leading cause of death. Hypertension (HT) increases the incidence of cardiac events, but its effect on cardiac adaptation to…”
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Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice by Zhang, Xin, Urbieta-Caceres, Victor H., Eirin, Alfonso, Bell, Caitlin C., Crane, John A., Tang, Hui, Jordan, Kyra L., Oh, Yun-Kyu, Zhu, Xiang-Yang, Korsmo, Michael J., Bachar, Adi R., Cohen, Pinchas, Lerman, Amir, Lerman, Lilach O.

“…Humanin (HN) is an endogenous mitochondrial-derived cytoprotective peptide that has shown protective effects against atherosclerosis and is expressed in human…”
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Patient comprehension of doctor-patient communication on discharge from the emergency department by Crane, John A.

“…An exit interview was conducted during March, 1994 on 314 patients treated and released from the Emergency Department at Kern Medical Center in Bakersfield,…”
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Abstract 54: Tissue Oxygenation Using Fractional Hypoxia Correlates Inversely With Blood Flow in Human Renovascular Disease (RVD) and Essential Hypertension (EH) by Saad, Ahmed, Crane, John A, Glockner, James, Herrmann, Sandra M, Ebrahimi, Behzad, Lerman, Lilach O, Textor, Stephen C

“…Abstract only Determinants of Intra-renal oxygenation in human RVD are poorly understood. Blood oxygen level-dependent (BOLD) MRI measures deoxyhemoglobin…”
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Abstract 222: Valsartan at a Sub-therapeutic Dose Ameliorates Myocardial Autophagy Overactivated in Renovascular Hypertension (RVH) by Zhang, Xin, Li, Zi-Lun, Pawar, Aditya S, Crane, John A, Eirin, Alfonso, Lerman, Amir, Lerman, Lilach O

“…Abstract only Objective: Excessive autophagy (degradation of intracellular structures) characterizes cardiomyocyte injury in hypertensive heart disease. The…”
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